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المصدر: Medicinal Chemistry. 18:323-336
مصطلحات موضوعية: Molecular Structure, Chemistry, Colorectal cancer, Cancer, Antineoplastic Agents, Biological activity, 2-Furanone, medicine.disease, Combinatorial chemistry, Structure-Activity Relationship, chemistry.chemical_compound, Breast cancer, 4-Butyrolactone, Heterocyclic Compounds, Cell Line, Tumor, Drug Discovery, medicine, Staurosporine, Drug Screening Assays, Antitumor, Cytotoxicity, Ovarian cancer, Cell Proliferation, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390b7ccb6fe183dad0e3bfcfc93a307eTest
https://doi.org/10.2174/1573406417666210604103135Test -
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المؤلفون: Mosaad S. Mohamed, Shahenda Mahgoub, Hend Medhat El-Shanbaky, Rania H. Abd El-Hameed, Sahar A. Ali
المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 977-986 (2021)مصطلحات موضوعية: Chemokine, medicine.drug_class, Inflammation, RM1-950, 01 natural sciences, Anti-inflammatory, Lipoxygenase, Structure-Activity Relationship, 4-Butyrolactone, Heterocyclic Compounds, Drug Discovery, medicine, Humans, 15-LOX inhibitors, Lipoxygenase Inhibitors, Pyridazinone, anti-inflammatory, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Cyclooxygenase 2 Inhibitors, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Tumor Necrosis Factor-alpha, TNF-α inhibitor, Anti-Inflammatory Agents, Non-Steroidal, General Medicine, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Biochemistry, Cyclooxygenase 2, biology.protein, Tumor necrosis factor alpha, selective COX-2 inhibitor, Cyclooxygenase, Therapeutics. Pharmacology, medicine.symptom, Research Article, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19667daf6d13bb3c9f348e6d97dfab69Test
http://europepmc.org/articles/PMC8118430Test -
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المصدر: Anti-Cancer Agents in Medicinal Chemistry. 21:963-986
مصطلحات موضوعية: Cancer Research, Cell Survival, Antineoplastic Agents, Tubulin Polymerization Inhibitors, Structure-Activity Relationship, Then test, Derivative (finance), Humans, Cytotoxic T cell, Benzopyrans, Spectral analysis, Protein Kinase Inhibitors, Cell Proliferation, Pharmacology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Sorafenib, Combinatorial chemistry, Tubulin Modulators, ErbB Receptors, Molecular Docking Simulation, Enzyme, Molecular Medicine, Drug Screening Assays, Antitumor, Colchicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6348d08811b1a4858f5c4ae8051f63Test
https://doi.org/10.2174/1871520620666200925103742Test -
4Design, Synthesis, Antitumor Activity and Molecular Docking Study of Novel 5-Deazaalloxazine Analogs
المؤلفون: Nageh A. Abou Taleb, Tomohisa Nagamatsu, Mosaad S. Mohamed, Mohamed A. Elsawy, Sawsan A. Mahmoud, Doaa Samaha, Hamed I. Ali
المصدر: Molecules, Vol 25, Iss 2518, p 2518 (2020)
Molecules
Volume 25
Issue 11مصطلحات موضوعية: Protein Data Bank (RCSB PDB), Pharmaceutical Science, Antineoplastic Agents, Apoptosis, deazaalloxazine, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, HeLa, Structure-Activity Relationship, 03 medical and health sciences, lcsh:Organic chemistry, Cell Line, Tumor, Flavins, Drug Discovery, Humans, Physical and Theoretical Chemistry, Protein kinase A, IC50, antitumor, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, 010405 organic chemistry, Organic Chemistry, selectivity, protein kinase, Protein-Tyrosine Kinases, AutoDock, biology.organism_classification, In vitro, 0104 chemical sciences, 540 Chemie und zugeordnete Wissenschaften, Enzyme, chemistry, Biochemistry, Chemistry (miscellaneous), Drug Design, ddc:540, MCF-7 Cells, Molecular Medicine, Drug Screening Assays, Antitumor, HeLa Cells
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e725485fd1446d8662406a1f8fffadcTest
https://doi.org/10.3390/molecules25112518Test -
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المصدر: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 33, Iss 1, Pp 755-767 (2018)
Journal of Enzyme Inhibition and Medicinal Chemistryمصطلحات موضوعية: 0301 basic medicine, Male, Models, Molecular, medicine.drug_class, Stereochemistry, Pyridines, 01 natural sciences, Anti-inflammatory, Rats, Sprague-Dawley, thieno[2,3-b]pyridine, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Drug Discovery, Pyridine, medicine, Structure–activity relationship, Animals, Edema, Cyclooxygenase Inhibitors, Lipoxygenase Inhibitors, 5-LOX, Conformational isomerism, Pharmacology, chemistry.chemical_classification, Arachidonate 5-Lipoxygenase, biology, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, COX-1, Anti-Inflammatory Agents, Non-Steroidal, lcsh:RM1-950, Active site, General Medicine, COX-2, 0104 chemical sciences, Rats, 030104 developmental biology, Enzyme, lcsh:Therapeutics. Pharmacology, Docking (molecular), Prostaglandin-Endoperoxide Synthases, biology.protein, Eicosanoids, Cyclooxygenase, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f5574537d8802e69dcb8974eb75ed5Test
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المؤلفون: Pratibha C. Koneru, Nivedita Jena, Pratiq A. Patel, Janet Antwi, Mosaad S. Mohamed, Matthew J. Kobe, Guqin Shi, Jacques J. Kessl, Lei Feng, Chenglong Li, James R. Fuchs, Nina Kvaratskhelia, Yara E. Mansour
مصطلحات موضوعية: 0301 basic medicine, Indoles, Stereochemistry, Dimer, Clinical Biochemistry, Allosteric regulation, Mutant, Pharmaceutical Science, HIV Integrase, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Allosteric Regulation, Drug Discovery, Structure–activity relationship, HIV Integrase Inhibitors, Molecular Biology, Indole test, biology, 010405 organic chemistry, Hydrogen bond, Organic Chemistry, Quinoline, Hydrogen Bonding, 0104 chemical sciences, Integrase, 030104 developmental biology, chemistry, biology.protein, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295e070ab652040d73122f41f53fbf44Test
https://europepmc.org/articles/PMC5018460Test/ -
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المؤلفون: Mosaad S. Mohamed, Mahmoud Youns, Naglaa Mohamed Ahmed
المصدر: European Journal of Medicinal Chemistry. 69:591-600
مصطلحات موضوعية: Antifungal Agents, Antioxidant, medicine.medical_treatment, Microbial Sensitivity Tests, Antioxidants, Thiouracil, Structure-Activity Relationship, chemistry.chemical_compound, Picrates, Drug Discovery, medicine, Organic chemistry, Pharmacology, Bacteria, Dose-Response Relationship, Drug, Molecular Structure, Vitamin C, Aryl, Biphenyl Compounds, Organic Chemistry, Fungi, Free Radical Scavengers, General Medicine, Carbon-13 NMR, Ascorbic acid, Antimicrobial, Anti-Bacterial Agents, chemistry, Proton NMR
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3cd67a2c4bb2fa8ff6de66c9a038f2Test
https://doi.org/10.1016/j.ejmech.2013.08.032Test -
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المؤلفون: Rania H. Abd El-Hameed, Mosaad S. Mohamed, Rehab Kamel
المصدر: Medicinal Chemistry Research. 22:2244-2252
مصطلحات موضوعية: Pyrimidine, Stereochemistry, Chemistry, medicine.drug_class, Organic Chemistry, Pharmacology toxicology, Mass spectrometry, Anti-inflammatory, chemistry.chemical_compound, In vivo, medicine, Proton NMR, Structure–activity relationship, General Pharmacology, Toxicology and Pharmaceutics
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::5a8be41ae9df3f15df017ce45644e8d8Test
https://doi.org/10.1007/s00044-012-0217-5Test -
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المؤلفون: Rania H. Abd El-Hameed, Peter Vella, Waleed M. Hussein, Ross P. McGeary, Gerhard Schenk, Mosaad S. Mohamed
المصدر: European Journal of Medicinal Chemistry. 46:6075-6082
مصطلحات موضوعية: medicine.drug_class, Klebsiella pneumoniae, Antibiotics, medicine.disease_cause, beta-Lactamases, Microbiology, Drug Discovery, medicine, Humans, Structure–activity relationship, Pseudomonas Infections, Pyrroles, Enzyme Inhibitors, Escherichia coli, Pharmacology, chemistry.chemical_classification, biology, Pseudomonas aeruginosa, Organic Chemistry, Active site, General Medicine, medicine.disease, biology.organism_classification, Klebsiella Infections, Enzyme, Biochemistry, chemistry, biology.protein, Klebsiella pneumonia, beta-Lactamase Inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bcf4b3a62ff3c08edf542302e889461Test
https://doi.org/10.1016/j.ejmech.2011.10.030Test -
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المؤلفون: Mosaad S. Mohamed, Samar S. Fatahala, Rehab Kamel
المصدر: European Journal of Medicinal Chemistry. 46:3022-3029
مصطلحات موضوعية: Pharmacology, Bicyclic molecule, Pyrimidine, Chemistry, Stereochemistry, Organic Chemistry, General Medicine, Chemical synthesis, Pyrrole derivatives, chemistry.chemical_compound, Drug Discovery, Structure–activity relationship, Pyrrole, Antibacterial agent
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f37f00565a8593a87f07846ad3719b47Test
https://doi.org/10.1016/j.ejmech.2011.04.034Test