نتائج البحث - "R. Charlotte Moffett"

1

Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu CreERT2;ROSA26-eYFP diabetic mice

المؤلفون: Dipak Sarnobat, Ryan A Lafferty, R Charlotte Moffett, Andrei I Tarasov, Peter R Flatt, Nigel Irwin

المصدر: Journal of Pharmacy and Pharmacology. 74:1758-1764

مصطلحات موضوعية: Blood Glucose, Pharmacology, Mice, Islets of Langerhans, Insulin-Secreting Cells, Cell Transdifferentiation, Animals, Insulin, Pharmaceutical Science, Artemether, Glucagon, Streptozocin, Diabetes Mellitus, Experimental

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a35bde8caa538348818407fb93f8e6a2Test
https://doi.org/10.1093/jpp/rgac075Test

2

GABA and insulin but not nicotinamide augment α- to β-cell transdifferentiation in insulin-deficient diabetic mice

المؤلفون: Dipak Sarnobat, R. Charlotte Moffett, Peter R. Flatt, Nigel Irwin, Andrei I. Tarasov

المصدر: Biochemical pharmacology. 199

مصطلحات موضوعية: Pharmacology, Blood Glucose, Niacinamide, Glucagon, Biochemistry, Streptozocin, Diabetes Mellitus, Experimental, Mice, Glucagon-Secreting Cells, Insulin-Secreting Cells, Cell Transdifferentiation, Animals, Insulin, gamma-Aminobutyric Acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b9134e9c688144c4776c68b8f290cbTest
https://pubmed.ncbi.nlm.nih.gov/35358478Test

3

Effects of long-acting analogues of lamprey GLP-1 and paddlefish glucagon on alpha- to beta-cell transdifferentiation in an insulin-deficient transgenic mouse model

المؤلفون: Galyna V. Graham, R. Charlotte Moffett, Peter R. Flatt, J. Michael Conlon, Yasser Abdel-Wahab

المصدر: Journal of peptide science : an official publication of the European Peptide SocietyREFERENCES. 27(8)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4214f415153797f05036487ad67f401Test
https://pubmed.ncbi.nlm.nih.gov/33843129Test

4

Positive Effects of NPY1 Receptor Activation on Islet Structure Are Driven by Pancreatic Alpha- and Beta-Cell Transdifferentiation in Diabetic Mice

المؤلفون: Neil Tanday, Frank Reimann, Peter R. Flatt, Nigel Irwin, Ryan A. Lafferty, R. Charlotte Moffett, Fiona M. Gribble

المساهمون: Apollo - University of Cambridge Repository, Reimann, Frank [0000-0001-9399-6377], Gribble, Fiona [0000-0002-4232-2898]

المصدر: Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 12 (2021)

مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, endocrine system diseases, transdifferentiation, Endocrinology, Diabetes and Metabolism, lcsh:Diseases of the endocrine glands. Clinical endocrinology, sea lamprey PYY, Mice, 0302 clinical medicine, Endocrinology, Insulin-Secreting Cells, peptide YY, Insulin, Neuropeptide Y, Petromyzon, Transgenes, Original Research, geography.geographical_feature_category, diabetes, Chemistry, Transdifferentiation, Cell Differentiation, Islet, medicine.anatomical_structure, Beta cell, medicine.drug, medicine.medical_specialty, endocrine system, Alpha (ethology), 030209 endocrinology & metabolism, Glucagon, streptozotocin, Streptozocin, Diabetes Mellitus, Experimental, 03 medical and health sciences, Islets of Langerhans, Bacterial Proteins, Internal medicine, medicine, Animals, geography, lcsh:RC648-665, Pancreatic islets, Streptozotocin, Mice, Inbred C57BL, Luminescent Proteins, 030104 developmental biology, Glucagon-Secreting Cells, Peptide YY, Peptides

وصف الملف: application/pdf; text/xml; application/zip

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8674da510487a4e5bdd491e17264b80Test
https://www.repository.cam.ac.uk/handle/1810/318655Test

5

Differential expression of glucagon-like peptide-2 (GLP-2) is involved in pancreatic islet cell adaptations to stress and beta-cell survival

المؤلفون: Dawood Khan, Nigel Irwin, R. Charlotte Moffett, Srividya Vasu, Peter R. Flatt

المصدر: Peptides. 95:68-75

مصطلحات موضوعية: 0301 basic medicine, endocrine system, medicine.medical_specialty, Hydrocortisone, Cell Survival, Physiology, Apoptosis, Biology, Biochemistry, Glucagon, Streptozocin, Alpha cell, Eating, Islets of Langerhans, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Glucagon-Like Peptide 2, medicine, Animals, Humans, Insulin, Intestinal Mucosa, Cell Proliferation, geography, geography.geographical_feature_category, digestive, oral, and skin physiology, Proglucagon, Glucagon-like peptide-2, Islet, Streptozotocin, Adaptation, Physiological, Intestines, Glucose, 030104 developmental biology, Somatostatin, Gene Expression Regulation, Glucagon-Like Peptide-2 Receptor, Beta cell, hormones, hormone substitutes, and hormone antagonists, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15d6b90245fe24e5ed2038a55540df3Test
https://doi.org/10.1016/j.peptides.2017.07.011Test

6

Dapagliflozin exerts positive effects on beta cells, decreases glucagon and does not alter beta- to alpha-cell transdifferentiation in mouse models of diabetes and insulin resistance

المؤلفون: Nigel Irwin, R. Charlotte Moffett, Neil Tanday, Peter R. Flatt

المصدر: Biochemical Pharmacology. 177:114009

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, medicine.medical_specialty, Hydrocortisone, Mice, Transgenic, Diet, High-Fat, Biochemistry, Glucagon, Streptozocin, Alpha cell, Diabetes Mellitus, Experimental, Islets of Langerhans, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Insulin resistance, Glucosides, Insulin-Secreting Cells, Diabetes mellitus, Internal medicine, medicine, Animals, Insulin, Benzhydryl Compounds, Dapagliflozin, Sodium-Glucose Transporter 2 Inhibitors, Homeodomain Proteins, Pharmacology, Body Weight, Transdifferentiation, medicine.disease, Streptozotocin, 030104 developmental biology, Endocrinology, chemistry, Glucagon-Secreting Cells, 030220 oncology & carcinogenesis, Cell Transdifferentiation, Trans-Activators, Insulin Resistance, Beta cell, Energy Intake, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983810c8b77150d2b2a250ebff3fbdfeTest
https://doi.org/10.1016/j.bcp.2020.114009Test

7

Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival

المؤلفون: Peter R. Flatt, Nigel Irwin, Dawood Khan, Srividya Vasu, R. Charlotte Moffett

المصدر: Molecular and cellular endocrinology. 436

مصطلحات موضوعية: 0301 basic medicine, Male, Hydrocortisone, Intracellular Space, Apoptosis, Biochemistry, Membrane Potentials, Endocrinology, Insulin-Secreting Cells, Insulin Secretion, Insulin, Cells, Cultured, geography.geographical_feature_category, digestive, oral, and skin physiology, Neuropeptide Y receptor, Islet, Beta cell, Somatostatin, PP cell, hormones, hormone substitutes, and hormone antagonists, medicine.drug, medicine.medical_specialty, Cell Survival, Biology, Pancreatic Polypeptide, Protective Agents, Glucagon, Streptozocin, Cell Line, 03 medical and health sciences, Insulin resistance, Internal medicine, medicine, Animals, Humans, Peptide YY, RNA, Messenger, Molecular Biology, Cell Proliferation, geography, Feeding Behavior, Glucose Tolerance Test, Streptozotocin, medicine.disease, Receptors, Neuropeptide Y, Mice, Inbred C57BL, 030104 developmental biology, Calcium, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74e38e0e7f36e4b8bd2b3ccb0636708bTest
https://pubmed.ncbi.nlm.nih.gov/27465830Test

8

Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells

المؤلفون: Peter R. Flatt, R. Charlotte Moffett, Neville H. McClenaghan, Srividya Vasu

المصدر: Journal of molecular endocrinology. 54(1)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6790fc6db35937535a5c896d3b25ee1eTest
https://pubmed.ncbi.nlm.nih.gov/25527608Test

9

Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress

المؤلفون: Srividya Vasu, Bernard Thorens, Peter R. Flatt, R. Charlotte Moffett

المصدر: PLoS ONE, Vol 9, Iss 6, p e101005 (2014)
PLoS One, vol. 9, no. 6, pp. e101005
PLoS ONE

مصطلحات موضوعية: Male, Hydrocortisone, endocrine system diseases, Physiology, lcsh:Medicine, Apoptosis, Alpha cell, Mice, 0302 clinical medicine, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Medicine and Health Sciences, Lymphocytes, lcsh:Science, Mice, Knockout, 0303 health sciences, Multidisciplinary, geography.geographical_feature_category, digestive, oral, and skin physiology, Islet, Glucagon-like peptide-1, Insulin oscillation, Protein Transport, Type 1 Diabetes, Beta cell, hormones, hormone substitutes, and hormone antagonists, Research Article, medicine.drug, medicine.medical_specialty, endocrine system, Incretin, 030209 endocrinology & metabolism, Gastric Inhibitory Polypeptide, Biology, Streptozocin, Islets of Langerhans, 03 medical and health sciences, Insulin resistance, Internal medicine, Diabetes Mellitus, medicine, Animals, Pancreas, Cell Proliferation, 030304 developmental biology, geography, Endocrine Physiology, lcsh:R, Biology and Life Sciences, Glucagon, medicine.disease, Streptozotocin, Hormones, Endocrinology, Metabolic Disorders, lcsh:Q, Insulin Resistance

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcee3c411f913f77f4ddeaf2bc1d427Test
http://europepmc.org/articles/PMC4072716?pdf=renderTest

تنقيح النتائج