يعرض 31 - 40 نتائج من 638 نتيجة بحث عن '"egfr inhibitors"', وقت الاستعلام: 0.97s تنقيح النتائج
  1. 31
    Dual Targeting EGFR and STAT3 With Erlotinib and Alantolactone Co-Loaded PLGA Nanoparticles for Pancreatic Cancer Treatment

    المؤلفون: Shihui Bao, Hailun Zheng, Jinyao Ye, Huirong Huang, Bin Zhou, Qing Yao, Guangyong Lin, Hailin Zhang, Longfa Kou, Ruijie Chen

    المصدر: Frontiers in Pharmacology
    Frontiers in Pharmacology, Vol 12 (2021)

    مصطلحات موضوعية: Pharmacology, biology, Chemistry, EGFR, lcsh:RM1-950, pancreatic cancer, medicine.disease, STAT3, lcsh:Therapeutics. Pharmacology, synergistic effect, Apoptosis, Pancreatic cancer, medicine, biology.protein, STAT protein, Cancer research, Pharmacology (medical), nanoparticles, Erlotinib, Epidermal growth factor receptor, Signal transduction, medicine.drug, EGFR inhibitors, Original Research

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbba3a8e10d2e35f262926fd1ff78e66Test
    http://europepmc.org/articles/PMC8017486Test


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  2. 32
    GABRP sustains the stemness of triple-negative breast cancer cells through EGFR signaling

    المؤلفون: Xiaoqi Wang, Honglei Zhang, Xiyin Li, Zongliu Hou, Hairui Wang, Jianyun Nie, Baowei Jiao, Jing Tan, Li Zou, Xing Yang, Lina Zhao, Qin Yang

    المصدر: Cancer letters. 514

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Colorectal cancer, Down-Regulation, Mice, Nude, Antineoplastic Agents, Triple Negative Breast Neoplasms, 03 medical and health sciences, Mice, 0302 clinical medicine, Gefitinib, Breast cancer, Cell Line, Tumor, Medicine, Animals, Humans, Doxorubicin, Epidermal growth factor receptor, Protein Kinase Inhibitors, Triple-negative breast cancer, EGFR inhibitors, biology, business.industry, Drug Synergism, medicine.disease, Receptors, GABA-A, ErbB Receptors, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Adjunctive treatment, Cancer research, biology.protein, Female, business, medicine.drug, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe95bed9a4f64f9ccbd1f8d6fce2804Test
    https://pubmed.ncbi.nlm.nih.gov/34023418Test


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  3. 33
    microRNA-7 inhibition protects human osteoblasts from dexamethasone via activation of epidermal growth factor receptor signaling

    المؤلفون: Wei Liu, Jian-Ning Zhao, Shengyu Cui, Xinhui Zhu, Zhiming Cui, Fan Jianbo

    المصدر: Molecular and Cellular Biochemistry. 460:113-121

    مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Clinical Biochemistry, Dexamethasone, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, medicine, Humans, Epidermal growth factor receptor, Molecular Biology, Protein kinase B, EGFR inhibitors, Osteoblasts, Cell Death, biology, Chemistry, Osteoblast, Cell Biology, General Medicine, Cytoprotection, Enzyme Activation, ErbB Receptors, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Proto-Oncogene Proteins c-akt, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf403d56f391c8030930371e1545d0aTest
    https://doi.org/10.1007/s11010-019-03575-yTest


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  4. 34
    Schizandrin A enhances the efficacy of gefitinib by suppressing IKKβ/NF-κB signaling in non-small cell lung cancer

    المؤلفون: Jiren Zhang, Haibing Xian, Weineng Feng

    المصدر: European Journal of Pharmacology. 855:10-19

    مصطلحات موضوعية: 0301 basic medicine, Lung Neoplasms, Cell cycle checkpoint, Protein Conformation, Apoptosis, IκB kinase, Molecular Dynamics Simulation, Lignans, Cyclooctanes, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Humans, Polycyclic Compounds, Receptor, EGFR inhibitors, Pharmacology, Cell growth, Chemistry, NF-kappa B, Drug Synergism, Cell Cycle Checkpoints, I-kappa B Kinase, respiratory tract diseases, IκBα, 030104 developmental biology, Cancer research, 030217 neurology & neurosurgery, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a3dcf5a8e530395d7f936c22794f0fTest
    https://doi.org/10.1016/j.ejphar.2019.04.016Test


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  5. 35
    p65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma

    المؤلفون: Roberto Giovannoni, Diego Cortinovis, Sara Bonomo, Silvano Bosari, Annamaria Cialdella, Irene Forno, Leonarda Ianzano, Gian-Luca Ferri, Emanuela Grassilli, Federica Brena, Maria Grazia Cerrito, Valentina Vaira, F. Damarco, Ennio Tasciotti, Silve Vicent, Federica Giordano, Marialuisa Lavitrano, Joyce Goedmakers

    المساهمون: Giordano, F, Vaira, V, Cortinovis, D, Bonomo, S, Goedmakers, J, Brena, F, Cialdella, A, Ianzano, L, Forno, I, Cerrito, M, Giovannoni, R, Ferri, G, Tasciotti, E, Vicent, S, Damarco, F, Bosari, S, Lavitrano, M, Grassilli, E

    المصدر: Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
    Journal of Experimental & Clinical Cancer Research : CR
    Dadun. Depósito Académico Digital de la Universidad de Navarra
    instname

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, medicine.medical_treatment, Gene Expression, medicine.disease_cause, NSCLC, Targeted therapy, Mice, 0302 clinical medicine, Agammaglobulinaemia Tyrosine Kinase, Protein Isoforms, EGFR inhibitors, BTK inhibitor, Drug Synergism, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Immunohistochemistry, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, EGFR inhibitor, Pemetrexed, Oncology, 030220 oncology & carcinogenesis, Erlotinib, KRAS, Ciencias de la Salud::Oncología [Materias Investigacion], medicine.drug, Signal Transduction, Cell Survival, EGFR, Adenocarcinoma of Lung, Antineoplastic Agents, lcsh:RC254-282, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, Gefitinib, Cell Line, Tumor, medicine, Biomarkers, Tumor, Animals, Humans, Chemotherapy, Lung cancer, Protein Kinase Inhibitors, Cell Proliferation, Neoplasm Staging, business.industry, Research, Cancer, medicine.disease, respiratory tract diseases, BTK inhibitors, 030104 developmental biology, Drug resistance, p65BTK, Mutation, Cancer research, business

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d42acbafac259cd31fb6a1e937e74b5dTest
    http://link.springer.com/article/10.1186/s13046-019-1199-7Test


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  6. 36
    EGFR/Notch Antagonists Enhance the Response to Inhibitors of the PI3K-Akt Pathway by Decreasing Tumor-Initiating Cell Frequency

    المؤلفون: Shi Hu, Ying Tang, Yue Yu, Wenyan Fu, Xuting Ye, Min Ding, Shuowu Liu, Yongji Yang, Fangxing Lin, Xiaoyan Fan, Changhai Lei, Tian Li, Yafeng Shen

    المصدر: Clinical Cancer Research. 25:2835-2847

    مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Indazoles, Cell, Notch signaling pathway, Mice, Nude, Apoptosis, Triple Negative Breast Neoplasms, Mice, SCID, Mice, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Cancer stem cell, Antibodies, Bispecific, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, Tumor Cells, Cultured, medicine, Animals, Humans, Tarextumab, PI3K/AKT/mTOR pathway, Cell Proliferation, EGFR inhibitors, Mice, Inbred BALB C, Sulfonamides, Receptors, Notch, Cell growth, business.industry, Prognosis, Xenograft Model Antitumor Assays, ErbB Receptors, Gene Expression Regulation, Neoplastic, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Cancer research, Signal transduction, business, Proto-Oncogene Proteins c-akt

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e312337e9377e2f908fcb32b441399eTest
    https://doi.org/10.1158/1078-0432.ccr-18-2732Test


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  7. 37
    Rationale for Using Irreversible Epidermal Growth Factor Receptor Inhibitors in Combination with Phosphatidylinositol 3-Kinase Inhibitors for Advanced Head and Neck Squamous Cell Carcinoma

    المؤلفون: Gabrielle Herbst, Aditi Kulkarni, Micah Harris, Thomas E. Carey, Hui Jiang, Jingyi Zhai, Elizabeth Leonard, J. Chad Brenner, Nicole L. Michmerhuizen, Chloe Matovina

    المصدر: Mol Pharmacol

    مصطلحات موضوعية: 0301 basic medicine, Pyridines, Receptor, ErbB-2, Afatinib, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, ErbB, Cell Line, Tumor, medicine, Humans, Epidermal growth factor receptor, Enzyme Inhibitors, Protein Kinase Inhibitors, neoplasms, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, EGFR inhibitors, Pharmacology, Sulfonamides, biology, Squamous Cell Carcinoma of Head and Neck, business.industry, Cancer, Articles, medicine.disease, Head and neck squamous-cell carcinoma, ErbB Receptors, 030104 developmental biology, Head and Neck Neoplasms, Quinazolines, Cancer research, biology.protein, Molecular Medicine, business, 030217 neurology & neurosurgery, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea354569229c66c25eb6ee728b79556bTest
    https://doi.org/10.1124/mol.118.115162Test


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  8. 38
    EGFR (Epidermal Growth Factor Receptor) Signaling and the Mitochondria Regulate sFlt-1 (Soluble FMS-Like Tyrosine Kinase-1) Secretion

    المؤلفون: Fiona C Brownfoot, Roxanne Hastie, Kirsten R Palmer, Sally Beard, Ping Cannon, Stephen Tong, Natalie J. Hannan, Vi Nguyen, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino

    المصدر: Hypertension. 73:659-670

    مصطلحات موضوعية: Placenta, Blood Pressure, 030204 cardiovascular system & hematology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Gefitinib, Pre-Eclampsia, Pregnancy, Internal Medicine, medicine, Humans, Secretion, Epidermal growth factor receptor, EGFR inhibitors, Vascular Endothelial Growth Factor Receptor-1, 030219 obstetrics & reproductive medicine, biology, Sirtuin 1, Kinase, Mitochondria, Cell biology, ErbB Receptors, Vasodilation, Vascular endothelial growth factor, Gene Expression Regulation, chemistry, embryonic structures, biology.protein, RNA, Female, Endothelium, Vascular, Soluble fms-like tyrosine kinase-1, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cd21e7317ca3a76132decf278dd334Test
    https://doi.org/10.1161/hypertensionaha.118.12300Test


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  9. 39
    Histone methyltransferase NSD2 mediates the survival and invasion of triple-negative breast cancer cells via stimulating ADAM9-EGFR-AKT signaling

    المؤلفون: Junjian Wang, Hong Wang, Hongwu Chen, Zhijian Duan, Peng Chen, Peiqing Liu, Jianzhen Xu, June X. Zou, Haibin Wang

    المصدر: Acta Pharmacol Sin

    مصطلحات موضوعية: 0301 basic medicine, Methyltransferase, medicine.medical_treatment, Mice, Nude, Triple Negative Breast Neoplasms, Biology, medicine.disease_cause, Article, Targeted therapy, 03 medical and health sciences, 0302 clinical medicine, Gefitinib, Cell Line, Tumor, medicine, Animals, Humans, Neoplasm Invasiveness, Pharmacology (medical), Triple-negative breast cancer, Cell Proliferation, EGFR inhibitors, Pharmacology, Mice, Inbred BALB C, Membrane Proteins, Histone-Lysine N-Methyltransferase, General Medicine, ErbB Receptors, Gene Expression Regulation, Neoplastic, Repressor Proteins, ADAM Proteins, 030104 developmental biology, Gene Knockdown Techniques, 030220 oncology & carcinogenesis, Histone methyltransferase, Cancer research, Carcinogenesis, ADAM9, Proto-Oncogene Proteins c-akt, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3aab6fa57b510ec03d6988b0731fd6Test
    https://doi.org/10.1038/s41401-018-0199-zTest


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  10. 40
    دورية أكاديمية
    PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment ... : تثبيط مستقبلات ألفا PDGF يحفز موت الخلايا المبرمج في الخلايا الجذعية لسرطان الورم الأرومي الدبقي المقاوم للعلاج المضاد للشق والمضاد لـ EGFR ...

    المؤلفون: Carlo Cenciarelli, Hany E. Marei, Manuela Zonfrillo, Pasquale Pierimarchi, Emanuela Paldino, Patrizia Casalbore, Armando Felsani, Angelo L. Vescovi, Giulio Maira, Annunziato Mangiola

    مصطلحات موضوعية: MicroRNA Regulation in Cancer and Development, Cancer Research, Biochemistry, Genetics and Molecular Biology, Life Sciences, Cancer Stem Cells and Tumor Metastasis, Oncology, Medicine, Health Sciences, Role of Long Noncoding RNAs in Cancer and Development, Stem Cell Niches, Cancer Stem Cells, Cancer research, Cancer stem cell, Notch signaling pathway, EGFR inhibitors, Biology, Stem cell, Targeted therapy, Epidermal growth factor receptor, Cell cycle, Cancer, Apoptosis, Notch 1, Signal transduction, Cell biology, Genetics, FOS Biological sciences, Biochemistry

    العلاقة: https://dx.doi.org/10.60692/e2xv9-npm06Test

    الإتاحة: https://doi.org/10.60692/jvgn8-1v07110.60692/e2xv9-npm06Test

    View record in BASE

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