المؤلفون: Shuanlong Cui, Xiaoguang Yao, Peng Yin, Xiangling Liao

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: Cancer Research, Cell, Cetuximab, Apoptosis, Biochemistry, Antineoplastic Agents, Immunological, Cell Movement, Epidermal growth factor receptor, EGFR inhibitors, Mitogen-Activated Protein Kinase 1, Mice, Inbred BALB C, Mitogen-Activated Protein Kinase 3, ERK1/2, biology, Chemistry, Drug Synergism, Articles, Blood Proteins, Cell cycle, Up-Regulation, oral squamous cell carcinoma, medicine.anatomical_structure, Oncology, Gene Knockdown Techniques, Carcinoma, Squamous Cell, Molecular Medicine, Mouth Neoplasms, Signal Transduction, medicine.drug, Galectins, Mice, Nude, resistance, Cell Line, Tumor, galectin-3, Genetics, medicine, Animals, Humans, Molecular Biology, Protein kinase B, Cell Proliferation, Oncogene, Akt, Xenograft Model Antitumor Assays, stomatognathic diseases, Drug Resistance, Neoplasm, Cancer research, biology.protein, epidermal growth factor receptor, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f88178b700b123540f3ced5b272189Test
https://doi.org/10.3892/mmr.2021.12325Test

المؤلفون: Yi-xuan Sun, An-mei Wang, Ailin Yang, Xiu-lian Li, Shaoping Wang, Yu-fan Tao, Zhong-dong Hu, Qi Wu, Jiayu Zhang, Long Dai

المصدر: Toxicology and applied pharmacology. 431

مصطلحات موضوعية: ERBB signaling pathway, Carcinoma, Hepatocellular, Down-Regulation, Antineoplastic Agents, Network Pharmacology, Toxicology, chemistry.chemical_compound, Gefitinib, Downregulation and upregulation, VEGF Signaling Pathway, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Gene Regulatory Networks, Protein Interaction Maps, Cinobufagin, Protein Kinase Inhibitors, EGFR inhibitors, Cell Proliferation, Pharmacology, Chemistry, Cyclin-Dependent Kinase 2, Liver Neoplasms, Cancer, Drug Synergism, Hep G2 Cells, medicine.disease, Bufanolides, ErbB Receptors, Gene Expression Regulation, Neoplastic, Purines, Cancer research, M Phase Cell Cycle Checkpoints, Signal transduction, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65633d5b0f93f8aacf79b4ce9eb1b092Test
https://pubmed.ncbi.nlm.nih.gov/34619160Test

المؤلفون: Jazlyn P. Borges, Katrina Mekhail, Gregory D. Fairn, Costin N. Antonescu, Benjamin E. Steinberg

المصدر: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

مصطلحات موضوعية: Disease, Review, membrane traffic, RM1-950, Bioinformatics, Receptor tyrosine kinase, 03 medical and health sciences, 0302 clinical medicine, medicine, Pharmacology (medical), Epidermal growth factor receptor, 030304 developmental biology, EGFR inhibitors, neuropathic pain, Pharmacology, 0303 health sciences, biology, business.industry, epidermai growth factor receptor, Chronic pain, Cancer, medicine.disease, animal models, 3. Good health, inflammation, Neuropathic pain, biology.protein, receptor tyrosine kinase, Therapeutics. Pharmacology, Signal transduction, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3694733d2e516bae69f79f35f4a7b14aTest

المؤلفون: George Dickson, Linda Popplewell, Farhat V N Din, Adam E. Hall, Kevin Myant, Malcolm G. Dunlop, Paz Freile, Alfonso Bolado, Caroline V. Billard, Victoria Gudiño, Stuart Aitken, Mark Agostino, David A. Stevenson, Douglas Strathdee, Laura Murphy, Owen J. Sansom, Alex von Kriegsheim, Sebastian Öther-Gee Pohl, John W. Cassidy, Patrizia Cammareri, Colin Nixon, Ann P. Wheeler

المساهمون: Pohl, Sebastian Öther-Gee [0000-0002-4294-9498], Aitken, Stuart [0000-0003-4867-4568], Agostino, Mark [0000-0002-1799-0392], Nixon, Colin [0000-0002-8085-2160], von Kriegsheim, Alex [0000-0002-4952-8573], Wheeler, Ann [0000-0001-8617-827X], Strathdee, Douglas [0000-0003-2959-4327], Sansom, Owen J [0000-0001-9540-3010], Myant, Kevin B [0000-0001-8017-1093], Apollo - University of Cambridge Repository

المصدر: Nature Communications
Gudiño, V, Öther-Gee Pohl, S, V Billard, C, Cammareri, P, Bolado Carrancio, A, Aitken, S, Stevenson, D, Hall, A, Agostino, M, Cassidy, J, Nixon, C, von Kriegsheim, A, Friele, P, Popplewell, L, Dickson, G, Murphy, L, Wheeler, A P, Dunlop, M G, Din, F V N, Strathdee, D, J. Sansom, O & Myant, K B 2021, ' Rac1b modulates intestinal tumourigenesis via modulation of Wnt and Egfr signalling pathways ', Nature Communications . https://doi.org/10.1038/s41467-021-22531-3Test
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: Male, rac1 GTP-Binding Protein, 0301 basic medicine, Cancer therapy, Carcinogenesis, Colorectal cancer, Cetuximab, General Physics and Astronomy, Mice, Antineoplastic Agents, Immunological, 0302 clinical medicine, Clinical efficacy, Cancer genetics, Wnt Signaling Pathway, EGFR inhibitors, Mice, Knockout, Egfr signalling, Multidisciplinary, Cancer stem cells, Wnt signaling pathway, Up-Regulation, ErbB Receptors, Gene Expression Regulation, Neoplastic, Cancer therapeutic resistance, 030220 oncology & carcinogenesis, Female, Colorectal Neoplasms, Signal Transduction, medicine.drug, Poor prognosis, Science, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Targeted therapies, Mediator, Cell Line, Tumor, medicine, Animals, Humans, business.industry, Neuropeptides, General Chemistry, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Drug Resistance, Neoplasm, Cancer research, business

وصف الملف: application/pdf; application/zip; text/xml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d761f8e664c9c0e74b157a8fb7baff43Test
https://eprints.gla.ac.uk/239120/1/239120.pdfTest

المؤلفون: Chih-Cheng Wu, Cheng-Yi Chang, Su-Lan Liao, Yu-Hsiang Kuan, Wen-Yi Wang, Ping-Ho Pan, Chun-Jung Chen, Wen-Ying Chen

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 8
International Journal of Molecular Sciences, Vol 22, Iss 3934, p 3934 (2021)

مصطلحات موضوعية: Catalysis, Article, Inorganic Chemistry, lcsh:Chemistry, Gefitinib, Cell Line, Tumor, glioma, medicine, Humans, ASK1, Epidermal growth factor receptor, Physical and Theoretical Chemistry, Molecular Biology, lcsh:QH301-705.5, neoplasms, Spectroscopy, EGFR inhibitors, biology, ATF6, Chemistry, Noxa, Endoplasmic reticulum, Organic Chemistry, apoptosis, General Medicine, Endoplasmic Reticulum Stress, Protein kinase R, Computer Science Applications, Neoplasm Proteins, lcsh:Biology (General), lcsh:QD1-999, Cancer research, Unfolded protein response, biology.protein, ER stress, medicine.drug, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27763355466d611d5720035a941d0db2Test

المؤلفون: Fabio Albuquerque Marchi, Eliney Ferreira Faria, Ademar Lopes, Luisa Matos do Canto, Mads M. Aagaard, Hellen Kuasne, Silvia Regina Rogatto, Cristovam Scapulatempo-Neto, Sébastien Carréno, Camille Valérie De Jamblinne, Juan José Augusto Moyano Muñoz

المصدر: Cells
Volume 10
Issue 4
Kuasne, H, Canto, L M D, Aagaard, M M, Muñoz, J J M, Jamblinne, C D, Marchi, F A, Scapulatempo-Neto, C, Faria, E F, Lopes, A, Carréno, S & Rogatto, S R 2021, ' Penile Cancer-Derived Cells Molecularly Characterized as Models to Guide Targeted Therapies ', Cells, vol. 10, no. 4, 814 . https://doi.org/10.3390/cells10040814Test
Cells, Vol 10, Iss 814, p 814 (2021)

مصطلحات موضوعية: Male, 0301 basic medicine, Cell, medicine.disease_cause, 0302 clinical medicine, Cell Movement, Molecular Targeted Therapy, lcsh:QH301-705.5, EGFR inhibitors, Aged, 80 and over, Cetuximab, CAFs, General Medicine, Middle Aged, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Erlotinib, Signal Transduction, medicine.drug, Adult, translatomic profile, Biology, Models, Biological, Article, 03 medical and health sciences, Gefitinib, Cell Line, Tumor, medicine, Humans, Penile cancer, Neoplasm Invasiveness, RNA, Messenger, Cell Shape, Penile Neoplasms, protein expression, PI3K/AKT/mTOR pathway, genomic profile, Aged, Cell Proliferation, cancer cell models, Genome, Human, Gene Expression Profiling, medicine.disease, penile cancer, 030104 developmental biology, lcsh:Biology (General), Protein Biosynthesis, Cancer research, Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe345412262d014ed225534b6e2a6adTest

المؤلفون: Yanying Chen, Xufeng Cen, Chao Zhang, Huanhuan Yan, Youqian Wu, Tingxue Xie, Huaying Zhu, Tingjun Hou, Songmin Ying, Ronghai Wu, Wei Chen, Hongguang Xia, Ayaz Najafov, Zhe Wang, Hongwei Liao, Zhengfu He, Qingwei Zhao, Qingxin Zeng, Xiaolan Liu, Mengmeng Zhang, Yaqin Sun, Xiaoyan Xu, Shuying Yang, Bing Shan

المصدر: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

مصطلحات موضوعية: 0301 basic medicine, Male, Molecular biology, medicine.medical_treatment, General Physics and Astronomy, B7-H1 Antigen, Glycogen Synthase Kinase 3, Mice, 0302 clinical medicine, Ubiquitin, Neoplasms, Cytotoxic T cell, CTLA-4 Antigen, Phosphorylation, EGFR inhibitors, Mice, Inbred BALB C, Multidisciplinary, biology, Chemistry, U937 Cells, Ubiquitin ligase, ErbB Receptors, 030220 oncology & carcinogenesis, Female, Immunotherapy, Signal transduction, Signal Transduction, Cell biology, Proteasome Endopeptidase Complex, Science, Ubiquitin-Protein Ligases, Mice, Nude, macromolecular substances, Models, Biological, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Immunity, PD-L1, medicine, Animals, Humans, Ubiquitination, General Chemistry, High-Throughput Screening Assays, 030104 developmental biology, HEK293 Cells, Proteolysis, biology.protein, Cancer research, Tumor Escape, Drug Screening Assays, Antitumor, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3c703fa4c5e444d1d89c4190f664d2Test
http://europepmc.org/articles/PMC8058344Test

المؤلفون: Jin Young Park, Sang-Hee Cho, Myung-Ju Ahn, Hwan Jung Yun, Jinpyo Kim, Gun-Do Kim, Bhumsuk Keam, Sangwoo Kim, Yunsuk Yu, Sang Hoon Chun, Tak Yun, Jung Hye Kwon, Hee Kyung Ahn, Joo Hang Kim, Ji Eun Kim, Ji Won Kim

المصدر: Processes, Vol 9, Iss 792, p 792 (2021)
Processes
Volume 9
Issue 5

مصطلحات موضوعية: 0301 basic medicine, precision medicine, Druggability, Bioengineering, TP1-1185, Biology, medicine.disease_cause, head and neck squamous cell carcinoma (HNSCC), 03 medical and health sciences, 0302 clinical medicine, medicine, Chemical Engineering (miscellaneous), Gene, QD1-999, EGFR inhibitors, Messenger RNA, Mutation, Process Chemistry and Technology, Chemical technology, medicine.disease, Head and neck squamous-cell carcinoma, pathway analysis, stomatognathic diseases, Chemistry, 030104 developmental biology, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, Cancer research, CBSJukebox, Signal transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4645ba731082e1aff7a95c3da409c96Test
https://www.mdpi.com/2227-9717/9/5/792Test

المؤلفون: Patricia Jauregui, Celia Sequera, Óscar Herranz, Ignacio Rubio, Carmen Guerrero, Alvaro Gutierrez-Uzquiza, Maria Rodrigo-Faus, Almudena Porras, Paloma Bragado, Stephanie Morgner, Sara Manzano

المساهمون: Ministerio de Economía y Competitividad (España), Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), Junta de Castilla y León, European Commission, Ministerio de Educación (España), Universidad Complutense de Madrid, Fundación BBVA, Comunidad de Madrid

المصدر: Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 4, Pp 1-17 (2021)
Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunology, Cell, Down-Regulation, Biology, Receptor tyrosine kinase, Article, Metastasis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Downregulation and upregulation, Cell Movement, Cell Line, Tumor, medicine, Humans, lcsh:QH573-671, Guanine Nucleotide-Releasing Factor 2, EGFR inhibitors, lcsh:Cytology, Brain Neoplasms, Fibroblast growth factor receptor 1, Receptor Protein-Tyrosine Kinases, Cell Biology, medicine.disease, CNS cancer, ErbB Receptors, 030104 developmental biology, medicine.anatomical_structure, Cell culture, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Guanine nucleotide exchange factor, Glioblastoma, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364976d4e004b3433dbe238ae0032450Test
http://europepmc.org/articles/PMC8024353Test

المؤلفون: Zhen Chen, Weilong Yao, Shi-Yong Sun, Suresh S. Ramalingam, Wen Zhao, Danlei Yu, Jin Yang

المصدر: Cancer letters. 519

مصطلحات موضوعية: Cancer Research, Lung Neoplasms, Apoptosis, MAP Kinase Kinase 5, Mice, Acquired resistance, In vivo, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, medicine, Animals, Humans, Osimertinib, Phosphorylation, Lung cancer, Protein Kinase Inhibitors, Mitogen-Activated Protein Kinase 7, EGFR inhibitors, Acrylamides, Aniline Compounds, Bcl-2-Like Protein 11, business.industry, medicine.disease, ErbB Receptors, Oncology, Cell culture, Drug Resistance, Neoplasm, Cancer research, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7becb12509cb9f9e64cdae6378e7ff89Test
https://pubmed.ncbi.nlm.nih.gov/34245854Test