نتائج البحث - "Kenneth P Nephew"

1

Retraction Note: EGFR and MET receptor tyrosine kinase–altered microRNA expression induces tumorigenesis and gefitinib resistance in lung cancers

المؤلفون: Michela Garofalo, Giulia Romano, Gianpiero Di Leva, Gerard Nuovo, Young-Jun Jeon, Apollinaire Ngankeu, Jin Sun, Francesca Lovat, Hansjuerg Alder, Gerolama Condorelli, Jeffrey A. Engelman, Mayumi Ono, Jin Kyung Rho, Luciano Cascione, Stefano Volinia, Kenneth P. Nephew, Carlo M. Croce

المصدر: Nat Med

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8b2af663fca1a79a4f6aaa08f34092Test
https://europepmc.org/articles/PMC9675728Test/

2

Constitutive activation of MEK5 promotes a mesenchymal and migratory cell phenotype in triple negative breast cancer

المؤلفون: Aaron Buechlein, Hope E. Burks, Van T. Hoang, Courtney K. Brock, Jane E. Cavanaugh, Jacqueline La, Steven Elliott, Patrick T. Flaherty, Matthew E. Burow, Margarite D. Matossian, Douglas B. Rusch, Kenneth P. Nephew, Bridgette M. Collins-Burow, Akshita B. Bhatt

المصدر: Oncoscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd24d23e6138d0cbd98efcb16596d0e1Test
https://doi.org/10.18632/oncoscience.535Test

3

A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways

المصدر: Anticancer Drugs

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Epithelial-Mesenchymal Transition, Lung Neoplasms, Apoptosis, Triple Negative Breast Neoplasms, Article, Metastasis, Small Molecule Libraries, Mice, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Biomarkers, Tumor, Tumor Cells, Cultured, Animals, Humans, Medicine, Pharmacology (medical), Epithelial–mesenchymal transition, Phosphorylation, Kinase activity, Protein Kinase Inhibitors, Triple-negative breast cancer, Cell Proliferation, Pharmacology, Molecular Structure, business.industry, Kinase, Cancer, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Cancer research, Female, Signal transduction, business, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5232d165c921188e2eb0b94b942d76ddTest
https://doi.org/10.1097/cad.0000000000000962Test

4

Targeting progesterone signaling prevents metastatic ovarian cancer

المصدر: Proc Natl Acad Sci U S A
PNAS

مصطلحات موضوعية: 0301 basic medicine, Adult, endocrine system diseases, Serous carcinoma, Salpingo-oophorectomy, Endogeny, Breast Neoplasms, 03 medical and health sciences, Mice, 0302 clinical medicine, Progesterone receptor, medicine, Animals, Humans, Breast, skin and connective tissue diseases, Gene, Progesterone, Ovarian Neoplasms, Multidisciplinary, Cancer prevention, Estradiol, business.industry, BRCA1 Protein, Ovary, Mifepristone, Neoplasms, Experimental, Biological Sciences, Middle Aged, medicine.disease, Cystadenocarcinoma, Serous, Disease Models, Animal, 030104 developmental biology, 030220 oncology & carcinogenesis, Mutation, Cancer research, Female, business, Ovarian cancer, Receptors, Progesterone, medicine.drug, Hormone, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6329d59a8fdd1cea8ebd6f4b537d481aTest
https://europepmc.org/articles/PMC7749341Test/

5

MicroRNA‐335‐5p and ‐3p synergize to inhibit estrogen receptor alpha expression and promote tamoxifen resistance

المؤلفون: Kenneth P. Nephew, Van T. Hoang, Elizabeth C. Martin, Bridgette M. Collins-Burow, Thomas J. Yan, Adrienne K. Conger, Aaron Buechlein, David F.B. Miller, Matthew E. Burow, Douglas B. Rusch

المصدر: FEBS Letters. 591:382-392

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, MAP Kinase Signaling System, Biophysics, Estrogen receptor, Breast Neoplasms, Biology, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Internal medicine, microRNA, Genetics, medicine, Humans, RNA, Messenger, Molecular Biology, Estrogen receptor beta, Regulation of gene expression, Estrogen Receptor alpha, High-Throughput Nucleotide Sequencing, Cell Biology, Non-coding RNA, Gene Expression Regulation, Neoplastic, MicroRNAs, Tamoxifen, 030104 developmental biology, Endocrinology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, MCF-7 Cells, Cancer research, Female, Signal transduction, Estrogen receptor alpha, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f26b5affb857e52df0939e7f21405dbTest
https://doi.org/10.1002/1873-3468.12538Test

6

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

المؤلفون: Daniela Matei, Yunlong Liu, David F.B. Miller, Kenneth P. Nephew, Tim H M Huang, Osman Nidai Ozes, Ali R. Özeş, Fang Fang

المصدر: Oncogene

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, DNA damage, Biology, Molecular oncology, Article, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, Genetics, Humans, DNA Breaks, Double-Stranded, Molecular Biology, Transcription factor, Cellular Senescence, Platinum, Ovarian Neoplasms, NF-kappa B, HOTAIR, Cell cycle, 3. Good health, Gene Expression Regulation, Neoplastic, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Female, RNA, Long Noncoding, Transcriptional Elongation Factors, Carrier Proteins, Cell aging, HOX Transcript Antisense RNA, DNA Damage, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7e4e16984143e9093e5645d0f1cc14Test
https://doi.org/10.1038/onc.2016.75Test

7

Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells

المؤلفون: Jun Wan, Aaron Buechlein, Sheng Liu, Qingchun Cai, Kenneth P. Nephew, Qipeng Fan, Yan Xu, David F.B. Miller

المصدر: PLoS ONE
PLoS ONE, Vol 13, Iss 6, p e0197404 (2018)

مصطلحات موضوعية: 0301 basic medicine, Molecular biology, Cell, lcsh:Medicine, Gene Expression, Apoptosis, Molecular biology assays and analysis techniques, Biochemistry, Mice, 0302 clinical medicine, Cell Movement, Gene expression, Medicine and Health Sciences, lcsh:Science, Regulation of gene expression, Ovarian Neoplasms, Multidisciplinary, Nucleic acid analysis, Gene Ontologies, Genomics, RNA analysis, Lipids, 3. Good health, Ovarian Cancer, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, medicine.anatomical_structure, Cell Transformation, Neoplastic, Oncology, 030220 oncology & carcinogenesis, Carbohydrate Metabolism, Female, Signal transduction, Research Article, Biology, 03 medical and health sciences, Cell Line, Tumor, medicine, Genetics, Animals, Humans, Gene Regulation, RNA, Messenger, Cell Proliferation, Cell growth, Sequence Analysis, RNA, lcsh:R, Cancer, Biology and Life Sciences, Cancers and Neoplasms, Computational Biology, medicine.disease, Lipid Metabolism, Genome Analysis, Research and analysis methods, 030104 developmental biology, Molecular biology techniques, Metabolism, Cell culture, Tumor progression, Cancer research, lcsh:Q, Gynecological Tumors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd065379c2a26bb45a6b81fca6bd4b16Test
http://europepmc.org/articles/PMC6013233Test

8

IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells

المؤلفون: Sumegha Mitra, Yinu Wang, Xingyue Zong, Daniela Matei, Anirban K. Mitra, Kenneth P. Nephew

المصدر: JCI insight. 3(23)

مصطلحات موضوعية: 0301 basic medicine, DNA (Cytosine-5-)-Methyltransferase 1, Epigenomics, STAT3 Transcription Factor, medicine.medical_treatment, Aldehyde Dehydrogenase 1 Family, 03 medical and health sciences, Mice, 0302 clinical medicine, Drug Therapy, Cell Line, Tumor, medicine, Tumor Microenvironment, Animals, Humans, Platinum, Ovarian Neoplasms, Tumor microenvironment, Mice, Inbred BALB C, biology, Chemistry, Interleukin-6, Cancer, Retinal Dehydrogenase, General Medicine, Neoplasms, Experimental, Aldehyde Dehydrogenase, DNA Methylation, medicine.disease, Up-Regulation, ALDH1A1, 030104 developmental biology, Cytokine, Hypomethylating agent, 030220 oncology & carcinogenesis, Cancer research, DNMT1, biology.protein, Azacitidine, Disease Progression, Neoplastic Stem Cells, Cytokines, Female, Immunotherapy, Stem cell, Ovarian cancer, Signal Transduction, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2f5f00596eda8e994c521598b862d7Test
https://pubmed.ncbi.nlm.nih.gov/30518684Test

9

Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers

المؤلفون: Tim H M Huang, Fei Gu, Nameer B. Kirma, Hui Chen Wang, Hsuan Cheng Huang, Mu Hsien Yu, Yu Ping Liao, Kenneth P. Nephew, Chun Liang Chen, Jianhua Ruan, Jay Pilrose, Cheng Chang Chang, Rui Lan Huang, Ian M. Thompson, Hung Cheng Lai

المصدر: Epigenetics

مصطلحات موضوعية: Cancer Research, Antineoplastic Agents, Nerve Tissue Proteins, Carcinoma, Ovarian Epithelial, Biology, Disease-Free Survival, Hedgehog pathway, Cell Line, Tumor, medicine, Animals, Humans, Hedgehog Proteins, Neoplasms, Glandular and Epithelial, Epigenetics, Progression-free survival, Promoter Regions, Genetic, Molecular Biology, Survival rate, Proportional Hazards Models, Ovarian Neoplasms, DNA methylation, Gene Expression Profiling, Promoter, Methylation, medicine.disease, Survival Analysis, 3. Good health, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Gene expression profiling, ovarian cancer, ZIC4, Cancer research, Female, ZIC1, Ovarian cancer, Signal Transduction, Transcription Factors, Research Paper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8915a77ac3f613801de3f3ec496890d9Test
https://doi.org/10.4161/epi.24816Test

10

The Organochlorine o,p’ -DDT Plays a Role in Coactivator-Mediated MAPK Crosstalk in MCF-7 Breast Cancer Cells

المؤلفون: Matthew E. Burow, Kenneth P. Nephew, Thomas E. Wiese, Melyssa R. Bratton, Daniel E. Frigo, H. Chris Segar, John A. McLachlan

المصدر: Environmental Health Perspectives

مصطلحات موضوعية: Insecticides, Cell signaling, animal structures, medicine.drug_class, Health, Toxicology and Mutagenesis, HIF-1α, Estrogen receptor, Endocrine Disruptors, Biology, CBP, p38 kinase, Polymerase Chain Reaction, crosstalk, DDT, 03 medical and health sciences, breast cancer, 0302 clinical medicine, parasitic diseases, Gene expression, Coactivator, medicine, Humans, endocrine-disrupting chemical, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, vascular endothelial growth factor, Estradiol, Research, organic chemicals, Public Health, Environmental and Occupational Health, MAPK, coactivator, 3. Good health, Vascular endothelial growth factor A, Gene Expression Regulation, Estrogen, dichlorodiphenyltrichloroethane, 030220 oncology & carcinogenesis, organochlorine, MCF-7 Cells, Cancer research, Female, Mitogen-Activated Protein Kinases, Signal transduction, Transcriptome, geographic locations, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864af45d292f1b906d966a19085c4ed6Test
https://doi.org/10.1289/ehp.1104296Test

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