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1دورية أكاديمية
المؤلفون: Jessica Mühlhaus, Juliane Dinter, Sabine Jyrch, Alexander Teumer, Simon F. Jacobi, Georg Homuth, Peter Kühnen, Susanna Wiegand, Annette Grüters, Henry Völzke, Klemens Raile, Gunnar Kleinau, Heiko Krude, Heike Biebermann
المصدر: Frontiers in Pharmacology, Vol 8 (2017)
مصطلحات موضوعية: trace amine-associated receptor 1, variants, weight regulation, glucose homeostasis, signal transduction, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: http://journal.frontiersin.org/article/10.3389/fphar.2017.00807/fullTest; https://doaj.org/toc/1663-9812Test
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المؤلفون: Susanna Wiegand, Barbara Wolters, Lex H.T. Van der Ploeg, Fred T. Fiedorek, K Mai, Katja Weiß, Heike Biebermann, Patrick Scheerer, Anne Müller, Peter Kühnen, Nicolas A. Heyder, Joachim Spranger, Gunnar Kleinau, Shubh D. Sharma, Oliver Blankenstein, Ulrike Blume-Peytavi, I. Sadaf Farooqi, Annette Grüters, Irina Jahnke, Heiko Krude, Jacek Mokrosinski, Keith Gottesdiener, Karine Clément, Lia Puder, Christine Poitou
المصدر: Nature Medicine. 24:551-555
مصطلحات موضوعية: 0301 basic medicine, Agonist, Setmelanotide, medicine.medical_specialty, Leptin Deficiency, medicine.drug_class, business.industry, Leptin, 030209 endocrinology & metabolism, NFAT, General Medicine, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Endocrinology, Weight loss, Internal medicine, medicine, Signal transduction, medicine.symptom, Receptor, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::006ce506a03e3c1266b9811152cde775Test
https://doi.org/10.1038/s41591-018-0015-9Test -
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المؤلفون: Lutz Schomburg, Josef Köhrle, Laura Kalveram, Annette Grüters-Kieslich, Heike Biebermann, Mariusz W. Szkudlinski, Gunnar Kleinau
المصدر: Molecular Endocrinology. 30:954-964
مصطلحات موضوعية: 0301 basic medicine, Agonist, endocrine system, medicine.drug_class, Mutant, Thyrotropin, 030209 endocrinology & metabolism, Biology, medicine.disease_cause, Chorionic Gonadotropin, Thyrotropin receptor, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, medicine, Humans, Receptor, Molecular Biology, Glycoproteins, Genetics, Mutation, Minireviews, General Medicine, Luteinizing Hormone, medicine.disease, Congenital hypothyroidism, 030104 developmental biology, Follicle Stimulating Hormone, Signal transduction, hormones, hormone substitutes, and hormone antagonists, Hormone
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0415d665f63a2a387870eb723a370cTest
https://doi.org/10.1210/me.2016-1065Test -
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المؤلفون: Anne Rediger, Carolin L. Piechowski, Anne Müller, Gunnar Kleinau, Juliane Pratzka, Jessica Mühlhaus, Heike Biebermann, Christina Lagemann, Patrick Tarnow, Heiko Krude, Annette Grüters
المصدر: Journal of Molecular Endocrinology. 51:109-118
مصطلحات موضوعية: Models, Molecular, Dimer, Receptor expression, Cell Membrane, Protein Structure, Secondary, Energy homeostasis, Melanocortin 4 receptor, chemistry.chemical_compound, Transmembrane domain, Endocrinology, Amino Acid Substitution, chemistry, Mutation, Biophysics, Animals, Receptor, Melanocortin, Type 4, Protein Multimerization, Receptor, Molecular Biology, Intracellular, Protein Binding, Signal Transduction, G protein-coupled receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fc1363e9ef57476a967ecd5ec30bcfTest
https://doi.org/10.1530/jme-13-0061Test -
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المؤلفون: Jessica Mühlhaus, Martin Klingenspor, Harald Brumm, S. Scherag, Johannes Hebebrand, Heike Biebermann, Anke Hinney, Susanna Wiegand, Florian Bolze, Heiko Krude, Annette Grüters
المصدر: Obesity. 20:1074-1081
مصطلحات موضوعية: Male, Endocrinology, Diabetes and Metabolism, Nonsense mutation, Mutant, Medizin, Medicine (miscellaneous), Biology, Endocrinology, Humans, Obesity, Receptor, Gene, Genetics, Oxadiazoles, Nutrition and Dietetics, Wild type, Stop codon, Cell biology, Melanocortin 4 receptor, Aminoglycosides, Blood-Brain Barrier, Codon, Nonsense, Codon, Terminator, Receptor, Melanocortin, Type 4, Female, Signal transduction, Energy Metabolism, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7816d403e052f25779dfc52229e0869Test
https://doi.org/10.1038/oby.2011.202Test -
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المؤلفون: Heike Biebermann, Daniela Handke, Heiko Krude, Peter Kühnen, Annette Grüters, Burkhard Wiesner, Gunnar Kleinau, Franziska Winkler, Jenny Eichhorst, Fergus J. Cameron, Burkhard Gerling, Anke Teichmann
المصدر: The Journal of Clinical Endocrinology & Metabolism. 97:E228-E232
مصطلحات موضوعية: medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Amino Acid Motifs, Clinical Biochemistry, Biology, Transfection, Biochemistry, Protein Structure, Secondary, Receptors, G-Protein-Coupled, Substrate Specificity, Thyrotropin receptor, Endocrinology, Catalytic Domain, Internal medicine, Helix (Snails), Chlorocebus aethiops, medicine, Animals, Humans, Child, Receptor, Conserved Sequence, G protein-coupled receptor, Genetics, Biochemistry (medical), Infant, Newborn, Receptors, Thyrotropin, Transmembrane domain, HEK293 Cells, Structural Homology, Protein, COS Cells, Mutation, Motif (music), Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca878b66eaaf946d0d01a888dadc5d2Test
https://doi.org/10.1210/jc.2011-2106Test -
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المؤلفون: Eva Rettenbacher, Kurt Widhalm, Johannes Hebebrand, Heike Biebermann, Anke Hinney, Harald Brumm, Patrick Tarnow, Petra Ambrugger, Michael Schaefer, Annette Grüters, Anne Rediger, Gerd Krause, Gunnar Kleinau
المصدر: Obesity Facts. 1:155-162
مصطلحات موضوعية: Adult, Male, Models, Molecular, Heterozygote, Health (social science), Adolescent, Mutant, Transfection, Physiology (medical), Chlorocebus aethiops, Animals, Humans, Medicine, Obesity, Receptor, Genes, Dominant, COS cells, business.industry, Wild type, Hydrogen Bonding, Heterozygote advantage, Middle Aged, Cell biology, Transmembrane domain, Child, Preschool, COS Cells, Mutation, Mutation (genetic algorithm), Receptor, Melanocortin, Type 4, Original Article, Female, Signal transduction, business, Dimerization, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54e6a42c15827f45fdbf7c2bbab6c74Test
https://doi.org/10.1159/000138251Test -
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المؤلفون: Anne Müller, Carolin S. Hoefig, Maxi Cöster, Carolin Leonie Wienchol, Heiko Krude, Jens Mittag, Jessica Mühlhaus, Annette Grüters, Torsten Schöneberg, Heike Biebermann, Jaroslawna Meister, Juliane Dinter, Josef Köhrle, Gunnar Kleinau, Simon Friedrich Jacobi
المصدر: Journal of molecular endocrinology. 54(3)
مصطلحات موضوعية: MAPK/ERK pathway, Male, Mice, 129 Strain, Adrenergic receptor, Drug Evaluation, Preclinical, Gene Expression, GTP-Binding Protein alpha Subunits, Gi-Go, Receptors, G-Protein-Coupled, 3-Iodothyronamine, chemistry.chemical_compound, Islets of Langerhans, Norepinephrine, Endocrinology, Receptors, Adrenergic, alpha-2, TAAR1, Adrenergic alpha-2 Receptor Agonists, Thyronines, Glucose homeostasis, Animals, Humans, Receptor, Molecular Biology, G protein-coupled receptor, Chemistry, Cell biology, Mice, Inbred C57BL, Glucose, HEK293 Cells, Signal transduction, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa88e1dab741a73ddd0ec8e5dea8c33aTest
https://pubmed.ncbi.nlm.nih.gov/25878061Test -
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المؤلفون: Josef Köhrle, Silke Morin, Juliane Dinter, Gunnar Kleinau, Matthias Tschöp, Jessica Mühlhaus, Daniela Nürnberg, Heiko Krude, Chun-Xia Yi, Heike Biebermann, Torsten Schöneberg, Carolin Leonie Wienchol, Annette Grüters
المساهمون: AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Endocrinology
المصدر: PLoS ONE, 10(2). Public Library of Science
PLoS ONE
PLoS ONE 10:e0117774 (2015)
PLoS ONE, Vol 10, Iss 2, p e0117774 (2015)مصطلحات موضوعية: medicine.medical_specialty, MAP Kinase Signaling System, G protein, lcsh:Medicine, Biology, Ligands, Cell Line, Receptors, G-Protein-Coupled, 3-Iodothyronamine, Mice, TAAR5, chemistry.chemical_compound, Internal medicine, TAAR1, Chlorocebus aethiops, Thyronines, medicine, Animals, Humans, lcsh:Science, Receptor, Trace amine-associated receptor, Mice, Knockout, Multidisciplinary, lcsh:R, Cell biology, Mice, Inbred C57BL, HEK293 Cells, Endocrinology, chemistry, COS Cells, Knockout mouse, lcsh:Q, Signal transduction, Signal Transduction, Research Article
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48002c58423e84de29ceaa46a955327eTest
https://pure.amc.nl/en/publications/inverse-agonistic-action-of-3iodothyronamine-at-the-human-trace-amineassociated-receptor-5Test(b83ca6e9-def8-45a8-8648-1535f3db2a7f).html -
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المؤلفون: Annette Grüters, Anne Müller, Jana Fischer, Timo D. Müller, Heike Biebermann, Vera Knäuper, Gunnar Kleinau, Matthias H. Tschöp, Brinja Leinweber
المصدر: BMC Res. Notes 7:913 (2014)
BMC Research Notesمصطلحات موضوعية: Models, Molecular, Molecular Sequence Data, Short Report, Biology, Q1, General Biochemistry, Genetics and Molecular Biology, Receptors, G-Protein-Coupled, Mice, GTP-Binding Proteins, Constitutive activation, Extracellular, Enzyme-linked receptor, Animals, Humans, Inverse agonist, Amino Acid Sequence, GABBR2, GABBR1, Receptor, Signaling mechanism, G protein-coupled receptor, Medicine(all), G-protein coupled receptor 83, Binding Sites, Sequence Homology, Amino Acid, Biochemistry, Genetics and Molecular Biology(all), Cell Membrane, Antagonist, General Medicine, Protein Structure, Tertiary, Cell biology, HEK293 Cells, Biochemistry, COS Cells, Mutation, Mitogen-Activated Protein Kinases, Signal transduction, Signal Transduction
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe2753fb0136feea7d2d766e964f645Test
https://doi.org/10.1186/1756-0500-7-913Test