المؤلفون: C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli.

المساهمون: C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli.

مصطلحات موضوعية: Cell signaling pathway, Drug-resistance, Metabolism, Mutation, Target therapie, Animal, Antineoplastic Agent, Glycogen Synthase Kinase 3, Human, Neoplasm, Protein Kinase Inhibitor, TOR Serine-Threonine Kinase, Signal Transduction

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31884070; info:eu-repo/semantics/altIdentifier/wos/WOS:000515431200015; volume:186; issue:4; firstpage:1; lastpage:10; numberofpages:10; journal:BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH; http://hdl.handle.net/11585/770839Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85078117886

الإتاحة: https://doi.org/10.1016/j.bbamcr.2019.118635Test
http://hdl.handle.net/11585/770839Test

المؤلفون: Francesca Paganelli, Camilla Evangelisti, Francesca Chiarini, Alberto M. Martelli

المساهمون: Francesca Chiarini, Francesca Paganelli, Alberto M Martelli, Camilla Evangelisti.

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 3, p 1098 (2020)
International Journal of Molecular Sciences

مصطلحات موضوعية: 0301 basic medicine, signaling pathway, medicine.medical_treatment, Review, acute lymphoblastic leukemia, leukemic stem cells, Catalysis, Targeted therapy, Inorganic Chemistry, lcsh:Chemistry, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Humans, Molecular Targeted Therapy, Physical and Theoretical Chemistry, Wnt Signaling Pathway, Molecular Biology, lcsh:QH301-705.5, Spectroscopy, Tissue homeostasis, Chemotherapy, business.industry, Organic Chemistry, Wnt signaling pathway, General Medicine, Precursor Cell Lymphoblastic Leukemia-Lymphoma, targeted therapy, leukemic stem cell, Hematopoiesis, Computer Science Applications, hematopoietic stem cells, Haematopoiesis, 030104 developmental biology, lcsh:Biology (General), lcsh:QD1-999, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, hematopoietic stem cell, Acute lymphoblastic leukemia, Hematopoietic stem cells, Leukemic stem cells, Signaling pathway, Wnt/β-catenin, Stem cell, Signal transduction, business, wnt/β-catenin

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff22a2ac54218f2340a65e0abf46eb1Test
https://www.mdpi.com/1422-0067/21/3/1098Test

المؤلفون: Alberto M. Martelli, Francesca Paganelli, Sandra Marmiroli, Francesca Chiarini, Camilla Evangelisti

المساهمون: C. Evangelisti, F. Chiarini, F. Paganelli, S. Marmiroli, Alberto M. Martelli.

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Protein Kinase Inhibitor, Antineoplastic Agents, Target therapies Drug-resistance Cell signaling pathways Metabolism Mutations, Targeted therapy, Antineoplastic Agent, 03 medical and health sciences, Cell signaling pathway, Glycogen Synthase Kinase 3, 0302 clinical medicine, Neoplasms, Animals, Humans, Medicine, Protein Kinase Inhibitors, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Drug-resistance, TOR Serine-Threonine Kinase, Cell growth, Kinase, business.industry, Animal, TOR Serine-Threonine Kinases, Cancer, Cell Biology, Target therapie, medicine.disease, 030104 developmental biology, Metabolism, 030220 oncology & carcinogenesis, Cancer cell, Mutation, Cancer research, Neoplasm, Signal transduction, business, Human, Signal Transduction

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7ed78981a6168532b38d4a17e47087Test
http://hdl.handle.net/11585/770839Test

المؤلفون: Francesca Paganelli, Francesca Chiarini, James A. McCubrey, Camilla Evangelisti, Alberto M. Martelli

المساهمون: A.M. Martelli, C. Evangelisti, F. Paganelli, F. Chiarini, J.A. McCubrey.

المصدر: Leukemia. 35(7)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, DNA repair, medicine.medical_treatment, macromolecular substances, Biology, Targeted therapy, 03 medical and health sciences, Glycogen Synthase Kinase 3, 0302 clinical medicine, acute leukemias, tumor suppressor, GSK-3, oncogene, medicine, Animals, Humans, Protein Isoforms, Leukemia, Kinase, Hematology, targeted therapy, 030104 developmental biology, proteasome, Oncology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Neoplastic cell, Phosphorylation, Signal transduction, Signal Transduction

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79bf19e2c9336426fc1f7c83fb9b6b5Test
https://pubmed.ncbi.nlm.nih.gov/33811246Test

المؤلفون: Tomoyuki Nakano, Toshiaki Tanaka, Yasukazu Hozumi, Kaoru Goto, Alberto M. Martelli

المساهمون: T. Tanaka, T. Nakano, Y. Hozumi, A.M. Martelli, K. Goto.

مصطلحات موضوعية: 0301 basic medicine, p53, Diacylglycerol Kinase, Phosphatidic Acids, CBP, Second Messenger Systems, NF-κB, Diglycerides, 03 medical and health sciences, Transactivation, chemistry.chemical_compound, 0302 clinical medicine, Animals, Humans, DGK, Molecular Biology, Transcription factor, Diacylglycerol kinase, Cell Nucleus, NF-kappa B, Cell Biology, Phosphatidic acid, Cell biology, Catalytic activity, Protein Transport, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Proteolysis, Second messenger system, Phosphorylation, Tumor Suppressor Protein p53, Signal transduction, Transcription

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4072cd85c5d99397ca4fbbb40bba0eabTest
http://hdl.handle.net/11585/827596Test

المؤلفون: Lucio Cocco, Linda S. Steelman, Giuseppe Montalto, Shaw M. Akula, Stephen L. Abrams, James A. McCubrey, Saverio Candido, Alberto M. Martelli, Agnieszka Gizak, Stefano Ratti, Dariusz Rakus, Massimo Libra, Melchiorre Cervello

المساهمون: S.L. Abrams, S.M. Akula, A.M. Martelli, L. Cocco, S. Ratti, M. Libra, S. Candido, G.Montalto, M. Cervello, A. Gizak, D. Rakus, L.S. Steelman, J.A. McCubrey.

المصدر: Advances in Biological Regulation
79 (2021). doi:10.1016/j.jbior.2020.100780
info:cnr-pdr/source/autori:Abrams SL; Akula SM; Martelli AM; Cocco L; Ratti S; Libra M; Candido S; Montalto G; Cervello M; Gizak A; Rakus D; Steelman LS; McCubrey JA;/titolo:Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53/doi:10.1016%2Fj.jbior.2020.100780/rivista:Advances in Biological Regulation (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:79

مصطلحات موضوعية: Male, 0301 basic medicine, Drug, Cancer Research, miRs, endocrine system diseases, media_common.quotation_subject, Signal transduction inhibitors, Targeted therapeutic, Antineoplastic Agents, Malignancy, medicine.disease_cause, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, 0302 clinical medicine, Chloroquine, Pancreatic cancer, Genetics, medicine, Humans, TP53, Molecular Biology, neoplasms, Signal transduction inhibitor, Targeted therapeutics, Cell Proliferation, media_common, target therapeutics, Cell growth, business.industry, Cancer, medicine.disease, digestive system diseases, Metformin, Pancreatic Neoplasms, 030104 developmental biology, 030220 oncology & carcinogenesis, Dietary Supplements, Mutation, Cancer research, Molecular Medicine, Female, KRAS, Tumor Suppressor Protein p53, business, Signal Transduction, medicine.drug, Drug sensitivity

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4dc94b168075da14e21c4cde71eb4bTest
http://hdl.handle.net/11585/855470Test

المؤلفون: Lucio Cocco, Przemysław Duda, Peter P. Ruvolo, Massimo Libra, Giuseppe Montalto, Agnieszka Gizak, Stefano Ratti, Melchiorre Cervello, Shaw M. Akula, Linda S. Steelman, Dariusz Rakus, Stephen L. Abrams, Alberto M. Martelli, Akshaya K. Meher, Saverio Candido, James A. McCubrey, Luca Falzone

المصدر: Cells 10 (2021). doi:10.3390/cells10040816
info:cnr-pdr/source/autori:Stephen L Abrams; Shaw M Akula; Akshaya K Meher; Linda S Steelman; Agnieszka Gizak; Przemys?aw Duda; Dariusz Rakus; Alberto M Martelli; Stefano Ratti; Lucio Cocco; Giuseppe Montalto; Melchiorre Cervello; Peter Ruvolo; Massimo Libra; Luca Falzone; Saverio Candido; James A McCubrey/titolo:GSK-3? Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals/doi:10.3390%2Fcells10040816/rivista:Cells/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Cells
Volume 10
Issue 4
Cells, Vol 10, Iss 816, p 816 (2021)

مصطلحات موضوعية: Berberine, endocrine system diseases, medicine.medical_treatment, Regulator, medicine.disease_cause, Deoxycytidine, Piperazines, Targeted therapy, chemotherapeutic drugs, Nitrophenols, Breast cancer, GSK-3B, Glycolysis, Molecular Targeted Therapy, Neoplasm Metastasis, targeted therapy, lcsh:QH301-705.5, Tumor Stem Cell Assay, Sulfonamides, Tumor, biology, Chemistry, General Medicine, Transfection, Metformin, Disease Progression, MCF-7 Cells, Female, KRAS, Nutraceuticals, Fluorouracil, Signal transduction, Signal Transduction, BCL2, bcl-X Protein, Antineoplastic Agents, Breast Neoplasms, macromolecular substances, Adenocarcinoma, Article, Cell Line, Inhibitory Concentration 50, Cell Line, Tumor, Thiadiazoles, medicine, Diabetes Mellitus, KRas, Humans, Glycogen synthase, Protein Kinase Inhibitors, Cell Proliferation, Chemotherapeu-tic drugs, Glycogen Synthase Kinase 3 beta, GSK-3β, Adenylate Kinase, Biphenyl Compounds, nutraceuticals, PDAC, β-catenin, Gemcitabine, ?-catenin, Malaria, Pancreatic Neoplasms, lcsh:Biology (General), MCF-7, Doxorubicin, Dietary Supplements, Cancer research, biology.protein

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9bc9ebd9624ff356255eb057b042a79Test
http://www.scopus.com/record/display.url?eid=2-s2.0-85105067732&origin=inwardTest

المؤلفون: Paolo Lombardi, Giuseppe Montalto, Lucio Cocco, Massimo Libra, Matilde L. Follo, James A. McCubrey, Shaw M. Akula, Stephen L. Abrams, Luca Falzone, Linda S. Steelman, Melchiorre Cervello, Saverio Candido, Stefano Ratti, Alberto M. Martelli

المساهمون: Abrams S.L., Akula S.M., Steelman L.S., Follo M.Y., Cocco L., Ratti S., Martelli A.M., Libra M., Falzone L., Candido S., Montalto G., Cervello M., Lombardi P., McCubrey J.A.

المصدر: Advances in Biological Regulation
83 (2022). doi:10.1016/j.jbior.2021.100840
info:cnr-pdr/source/autori:Abrams S.L.; Akula S.M.; Steelman L.S.; Follo M.L.; Cocco L.; Ratti S.; Martelli A.M.; Libra M.; Falzone L.; Candido S.; Montalto G.; Cervello M.; Lombardi P.; McCubrey J.A./titolo:Effects of the MDM2 inhibitor Nutlin-3a on sensitivity of pancreatic cancer cells to berberine and modified berberines in the presence and absence of WT-TP53/doi:10.1016%2Fj.jbior.2021.100840/rivista:Advances in Biological Regulation (Print)/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:83

مصطلحات موضوعية: Nutlin-3a, Cancer Research, Berberine, endocrine system diseases, Tumor suppressor gene, NAX compounds, Apoptosis, Piperazines, Targeted therapy, Gene product, Cell Line, Tumor, Pancreatic cancer, Genetics, medicine, Humans, TP53, neoplasms, Molecular Biology, Regulator gene, NAX compunds, biology, Chemistry, Imidazoles, PDAC, Cancer, Proto-Oncogene Proteins c-mdm2, PDCA, medicine.disease, Ubiquitin ligase, Pancreatic Neoplasms, Cell culture, biology.protein, Cancer research, NAX compound, Molecular Medicine, Mdm2, Tumor Suppressor Protein p53, Signal Transduction

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044ed944dafd4c9e8a9fbd076f5ea049Test
https://doi.org/10.1016/j.jbior.2021.100840Test

المؤلفون: Linda S. Steelman, Giuseppe Montalto, Melchiorre Cervello, Stefano Ratti, James A. McCubrey, Shaw M. Akula, Stephen L. Abrams, Saverio Candido, Massimo Libra, Agnieszka Gizak, Dariusz Rakus, Przemysław Duda, Alberto M. Martelli, Lucio Cocco

المساهمون: Duda P., Akula S.M., Abrams S.L., Steelman L.S., Martelli A.M., Cocco L., Ratti S., Candido S., Libra M., Montalto G., Cervello M., Gizak A., Rakus D., McCubrey J.A.

المصدر: Cells 9 (2020). doi:10.3390/cells9051110
info:cnr-pdr/source/autori:Duda P; Akula SM; Abrams SL; Steelman LS; Martelli AM; Cocco L; Ratti S; Candido S; Libra M; Montalto G; Cervello M; Gizak A; Rakus D; McCubrey JA;/titolo:Targeting GSK3 and Associated Signaling Pathways Involved in Cancer/doi:10.3390%2Fcells9051110/rivista:Cells/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Cells
Cells, Vol 9, Iss 1110, p 1110 (2020)

مصطلحات موضوعية: natural product, natural products, mTORC1, Review, macromolecular substances, Protein Serine-Threonine Kinases, Glycogen Synthase Kinase 3, GSK-3, Neoplasms, Humans, Phosphorylation, Protein kinase A, Glycogen synthase, lcsh:QH301-705.5, Protein kinase B, Wnt Signaling Pathway, PI3K/AKT/mTOR pathway, drug resistance, naturalproducts, biology, Chemistry, Wnt signaling pathway, General Medicine, targeted therapy, Cell biology, lcsh:Biology (General), biology.protein, Signal transduction, Proto-Oncogene Proteins c-akt

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8923824ed0e007bf68e148036bea96b2Test
http://www.cnr.it/prodotto/i/425334Test

المؤلفون: Monica Notarbartolo, Jörg Bäsecke, Massimo Libra, Giuseppe Montalto, Melchiorre Cervello, Linda S. Steelman, James A. McCubrey, Alberto M. Martelli, Giulia Ramazzotti, Lucio Cocco, Saverio Candido, Shaw M. Akula, Kvin Lerpiriyapong, Stephen L. Abrams, William L. Blalock, Stefano Ratti, Manuela Piazzi, Matilde Y. Follo

المساهمون: Akula S.M., Abrams S.L., Steelman L.S., Candido S., Libra M., Lerpiriyapong K., Cocco L., Ramazzotti G., Ratti S., Follo M.Y., Martelli A.M., Blalock W.L., Piazzi M., Montalto G., Cervello M., Notarbartolo M., Basecke J., McCubrey J.A.

المصدر: Advances in Biological Regulation
77 (2020). doi:10.1016/j.jbior.2020.100739
info:cnr-pdr/source/autori:Shaw MAkula; Stephen L Abrams; Linda SSteelman; SaverioCandido; MassimoLibra; KvinLerpiriyapong; LucioCocco; GiuliaRamazzotti; Stefano Ratti; Matilde YFollo; Alberto MMartelli; William L Blalock; Manuela Piazzi; Giuseppe Montalto; Melchiorre Cervello; Monica Notarbartolo; Jorg Basecke; James A McCubrey;/titolo:Cancer therapy and treatments during COVID-19 era/doi:10.1016%2Fj.jbior.2020.100739/rivista:Advances in Biological Regulation (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:77

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Disease, Comorbidity, Antineoplastic Agent, 0302 clinical medicine, Repurposing approved drug, Neoplasms, Pandemic, Medicine, Viral, Cancer, Natural products, Vitamins, Spike Glycoprotein, Host-Pathogen Interaction, Drug repositioning, 030220 oncology & carcinogenesis, Host-Pathogen Interactions, Spike Glycoprotein, Coronavirus, Molecular Medicine, Nutraceutical, Angiotensin-Converting Enzyme 2, Nutraceuticals, Coronavirus Infections, Human, Hydroxychloroquine, Signal Transduction, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Pneumonia, Viral, Antineoplastic Agents, Peptidyl-Dipeptidase A, Antiviral Agents, Natural product, Vitamin, Article, 03 medical and health sciences, Betacoronavirus, Genetics, Humans, Intensive care medicine, Molecular Biology, Pandemics, Trace Element, Antiviral Agent, Betacoronaviru, Coronavirus Infection, business.industry, SARS-CoV-2, Cance, Repurposing approved drugs, Drug Repositioning, rNatural products, COVID-19, Pneumonia, medicine.disease, Review article, Trace Elements, Coronavirus, 030104 developmental biology, Gene Expression Regulation, Settore BIO/14 - Farmacologia, Neoplasm, business, Spike Glycoprotein, Coronaviru

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c69c323af20dd5a069b199c4e1e36d7Test
http://www.cnr.it/prodotto/i/432820Test