نتائج البحث - "Agostina Nardone"

1

Activation of the IFN Signaling Pathway is Associated with Resistance to CDK4/6 Inhibitors and Immune Checkpoint Activation in ER-Positive Breast Cancer

المساهمون: De Angelis, C., Fu, X., Cataldo, M. L., Nardone, A., Pereira, R., Veeraraghavan, J., Nanda, S., Qin, L., Sethunath, V., Wang, T., Hilsenbeck, S. G., Benelli, M., Migliaccio, I., Guarducci, C., Malorni, L., Litchfield, L. M., Liu, J., Donaldson, J., Selenica, P., Brown, D. N., Weigelt, B., Reis-Filho, J. S., Park, B. H., Hurvitz, S. A., Slamon, D. J., Rimawi, M. F., Jansen, V. M., Jeselsohn, R., Osborne, C. K., Schiff, R.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research, vol 27, iss 17

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Pyridines, Oncology and Carcinogenesis, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, Palbociclib, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Immune system, Breast cancer, Receptors, Breast Cancer, Genetics, Tumor Cells, Cultured, Humans, Medicine, Oncology & Carcinogenesis, Cancer, Cultured, biology, business.industry, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, medicine.disease, Estrogen, Immune checkpoint, Tumor Cells, Good Health and Well Being, 030104 developmental biology, Receptors, Estrogen, Oncology, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Female, Cyclin-dependent kinase 6, Development of treatments and therapeutic interventions, Signal transduction, business, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d5dea84c01cc54303c5f5ebf7c4dcTest
https://doi.org/10.1158/1078-0432.ccr-19-4191Test

2

Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer

المساهمون: Sethunath, Vidyalakshmi, Hu, Huizhong, DE ANGELIS, Carmine, Veeraraghavan, Jamunarani, Qin, Lanfang, Wang, Nichola, Simon, Lukas M, Wang, Tao, Fu, Xiaoyong, Nardone, Agostina, Pereira, Resel, Nanda, Sarmistha, Griffith, Obi L, Tsimelzon, Anna, Shaw, Chad, Chamness, Gary C, Reis-Filho, Jorge S, Weigelt, Britta, Heiser, Laura M, Hilsenbeck, Susan G, Huang, Shixia, Rimawi, Mothaffar F, Gray, Joe W, Osborne, C Kent, Schiff, Rachel

المصدر: Mol Cancer Res
Mol. Cancer Res. 17, 2318-2330 (2019)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Geranylgeranyl pyrophosphate, Receptor, ErbB-2, Farnesyl pyrophosphate, Mevalonic Acid, Antineoplastic Agents, Apoptosis, Breast Neoplasms, Mechanistic Target of Rapamycin Complex 1, Lapatinib, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Survivin, Humans, Medicine, Phosphorylation, skin and connective tissue diseases, neoplasms, Molecular Biology, business.industry, Cell growth, Trastuzumab, 030104 developmental biology, Oncology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Female, Mevalonate pathway, Growth inhibition, business, Signal Transduction, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47e32d952d195af7dec86930048dfc3Test
https://doi.org/10.1158/1541-7786.mcr-19-0756Test

3

The changing role of ER in endocrine resistance

المؤلفون: Agostina Nardone, Carmine De Angelis, Meghana V. Trivedi, C. Kent Osborne, Rachel Schiff

المساهمون: Nardone, A., De Angelis, C., Trivedi, M. V., Osborne, C. K., Schiff, R.

المصدر: The Breast. 24:S60-S66

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14b3567fe1a4024b41f0048bda524accTest
https://doi.org/10.1016/j.breast.2015.07.015Test

4

Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy

المساهمون: Giuliano, Mario, Hu, H, Wang, Yc, Fu, X, Nardone, Agostina, Herrera, S, Mao, S, Contreras, A, Gutierrez, C, Wang, T, Hilsenbeck, Sg, DE ANGELIS, Carmine, Wang, Nj, Heiser, Lm, Gray, Jw, Lopez Tarruella, S, Pavlick, Ac, Trivedi, Mv, Chamness, Gc, Chang, Jc, Osborne, Ck, Rimawi, Mf, Schiff, R.

المصدر: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Time Factors, Antineoplastic Agents, Hormonal, Cell Survival, Receptor, ErbB-2, medicine.medical_treatment, Gene Expression, Estrogen receptor, Breast Neoplasms, Lapatinib, Article, Mice, Downregulation and upregulation, Cell Line, Tumor, Internal medicine, Animals, Humans, Medicine, Molecular Targeted Therapy, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Neoadjuvant therapy, biology, Fulvestrant, business.industry, Cancer, medicine.disease, Xenograft Model Antitumor Assays, Neoadjuvant Therapy, Disease Models, Animal, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Receptors, Estrogen, Oncology, Drug Resistance, Neoplasm, Tumor progression, Quinazolines, Cancer research, biology.protein, Female, Receptors, Progesterone, business, Biomarkers, Signal Transduction, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b1598f486d1beb5e4551a1d1f12f3dTest
https://doi.org/10.1158/1078-0432.ccr-14-2728Test

5

HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer

المساهمون: Xu, X., De Angelis, C., Burke, K. A., Nardone, A., Hu, H., Qin, L., Veeraraghavan, J., Sethunath, V., Heiser, L. M., Wang, N., Ng, C. K. Y., Chen, E. S., Renwick, A., Wang, T., Nanda, S., Shea, M., Mitchell, T., Rajendran, M., Waters, I., Zabransky, D. J., Scott, K. L., Gutierrez, C., Nagi, C., Geyer, F. C., Chamness, G. C., Park, B. H., Shaw, C. A., Hilsenbeck, S. G., Rimawi, M. F., Gray, J. W., Weigelt, B., Reis-Filho, J. S., Osborne, C. K., Schiff, R.

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Xenograft Model Antitumor Assay, Receptor, ErbB-2, Afatinib, medicine.medical_treatment, Breast Neoplasms, Biology, Lapatinib, Antibodies, Monoclonal, Humanized, Article, Targeted therapy, 03 medical and health sciences, Mice, 0302 clinical medicine, Germline mutation, Breast cancer, Trastuzumab, Cell Line, Tumor, medicine, Animals, Humans, Molecular Targeted Therapy, skin and connective tissue diseases, Cell Proliferation, Animal, Cancer, Quinazoline, medicine.disease, Xenograft Model Antitumor Assays, 030104 developmental biology, Oncology, Receptors, Estrogen, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Immunology, Neratinib, Mutation, Cancer research, Quinazolines, Female, Breast Neoplasm, medicine.drug, Human, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb068280b301594f2965d31acd31789Test
https://europepmc.org/articles/PMC5762201Test/

6

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

المؤلفون: Nicholas Mitsiades, Rainer B. Lanz, Cristian Coarfa, Chad J. Creighton, Zheng Zhang, Yongcheng Song, Xiaoyong Fu, Bert W. O'Malley, C. Kent Osborne, Qin Feng, Constantine S. Mitsiades, Bin He, Agostina Nardone, James E. Bradner, Martin Shea, Rachel Schiff, Lei Wang, Susan G. Hilsenbeck

المصدر: Cell Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c16f2d3cdf58d637fb10ef1da2be07Test
https://doi.org/10.1038/cr.2014.71Test

7

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

المساهمون: Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V., Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K., Schiff, R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 113(43)

مصطلحات موضوعية: 0301 basic medicine, Hepatocyte Nuclear Factor 3-alpha, Antineoplastic Agents, Hormonal, Prognosi, Estrogen receptor, Breast Neoplasms, Biology, Transcriptome, 03 medical and health sciences, Breast cancer, Cell Line, Tumor, medicine, Humans, RNA, Small Interfering, Gene knockdown, Multidisciplinary, Pioneer factor, Interleukin-8, Estrogen Receptor alpha, medicine.disease, Prognosis, Survival Analysis, Gene Expression Regulation, Neoplastic, Tamoxifen, 030104 developmental biology, PNAS Plus, Drug Resistance, Neoplasm, Transcriptional reprogramming, Cancer research, Female, Survival Analysi, FOXA1, Estrogen receptor alpha, Breast Neoplasm, Endocrine resistance, Human, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2387c3c513051ae7743e2ef46a0318Test
https://pubmed.ncbi.nlm.nih.gov/27791031Test

8

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

المساهمون: Fu, Xiaoyong, Creighton, Chad J., Biswal, Nrusingh C., Kumar, Vijetha, Shea, Martin, Herrera, Sabrina, Contreras, Alejandro, Gutierrez, Carolina, Wang, Tao, Nanda, Sarmistha, Giuliano, Mario, Morrison, Glady, Nardone, Agostina, Karlin, Kristen L., Westbrook, Thomas F., Heiser, Laura M., Anur, Pavana, Spellman, Paul, Guichard, Sylvie M., Smith, Paul D., Davies, Barry R., Klinowska, Teresa, Lee, Adrian V., Mills, Gordon B., Rimawi, Mothaffar F., Hilsenbeck, Susan G., Gray, Joe W., Joshi, Amit, Osborne, C. K., Schiff, Rachel

المصدر: Breast Cancer Research : BCR

مصطلحات موضوعية: Cancer Research, Gene Expression, Mitogen-activated protein kinase kinase, Mitogen-Activated Protein Kinase, Phosphatidylinositol 3-Kinases, MCF-7 Cell, Sirolimu, ASK1, Molecular Targeted Therapy, Fulvestrant, Medicine(all), TOR Serine-Threonine Kinase, biology, Estradiol, TOR Serine-Threonine Kinases, 3. Good health, Editorial, Oncology, Receptors, Estrogen, Doxycycline, Gene Knockdown Techniques, MCF-7 Cells, Female, Mitogen-Activated Protein Kinases, Breast Neoplasm, Research Article, Human, Signal Transduction, Xenograft Model Antitumor Assay, Neoplasms, Hormone-Dependent, Antineoplastic Agents, Hormonal, Protein Kinase Inhibitor, Mice, Nude, Breast Neoplasms, PTEN, Animals, Humans, c-Raf, Protein kinase B, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Sirolimus, Animal, Cyclin-dependent kinase 4, Akt/PKB signaling pathway, PTEN Phosphohydrolase, Xenograft Model Antitumor Assays, Tamoxifen, Drug Resistance, Neoplasm, Gene Knockdown Technique, biology.protein, Cancer research, Phosphatidylinositol 3-Kinase, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b8e05d376b25b5859d608cc00f5d0fTest
https://pubmed.ncbi.nlm.nih.gov/25888162Test

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