المؤلفون: Marius K. Lemberg, Sara Suna Yucel

المصدر: Journal of Molecular Biology. 432:5063-5078

مصطلحات موضوعية: Proteases, Proteolysis, Protein degradation, Endoplasmic Reticulum, Regulated Intramembrane Proteolysis, Presenilin, 03 medical and health sciences, 0302 clinical medicine, Structural Biology, Catalytic Domain, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Molecular Biology, Phylogeny, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, medicine.diagnostic_test, Chemistry, Endoplasmic reticulum, Cell Membrane, Protein Transport, Enzyme, Biochemistry, Signal peptide peptidase, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78def52d2d9b8d5c1f99092ec8ac4674Test
https://doi.org/10.1016/j.jmb.2020.05.014Test

المؤلفون: Hester A. Beard, Christian Lüchtenborg, Marta Barniol-Xicota, Dipali Kale, Britta Brügger, Marius K. Lemberg, Dönem Avci, Ronny Heidasch, Bernd Schröder, Steven H. L. Verhelst, Torben Mentrup

مصطلحات موضوعية: biology, Intramembrane protease, Allosteric regulation, Ubiquitin ligase, Cell biology, chemistry.chemical_compound, Metabolic pathway, Biosynthesis, chemistry, biology.protein, Transcriptional regulation, lipids (amino acids, peptides, and proteins), Mevalonate pathway, Signal peptide peptidase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::cfbf125666e1a7d4c2ac8c9c5ee55030Test
https://doi.org/10.1101/2021.07.19.452877Test

المؤلفون: Nathalie Kühnle, Verena Dederer, Marius K. Lemberg

المصدر: Journal of cell science. 132(16)

مصطلحات موضوعية: 0303 health sciences, Proteases, Cell Membrane, Membrane Proteins, Cell Biology, Protein degradation, Biology, Regulated Intramembrane Proteolysis, Presenilin, Cell biology, 03 medical and health sciences, 0302 clinical medicine, Organelle, Proteolysis, Animals, Humans, Protein maturation, Signal peptide peptidase, 030217 neurology & neurosurgery, Cellular compartment, 030304 developmental biology, Peptide Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0b6ab3652bdd9b000d0c2def227750Test
https://pubmed.ncbi.nlm.nih.gov/31416853Test

المؤلفون: Vivian Adamski, Torben Mentrup, Regina Fluhrer, Martina Haug-Kröper, Uddipta Biswas, Rolf Jessberger, Ronny Heidasch, Verena Dederer, Bernd Schröder, Paul Saftig, Alkmini A Papadopoulou, Rieke Meyer, Stefan F. Lichtenthaler, Johannes Niemeyer, Renate Lüllmann-Rauch, Martin Bergmann, Artur Mayerhofer, Gunther Wennemuth, Marius K. Lemberg, Stephan A. Müller

المصدر: EMBO reports 20(3), e46449 (2019). doi:10.15252/embr.201846449

مصطلحات موضوعية: Male, medicine.medical_treatment, Medizin, Biochemistry, Substrate Specificity, Mice, 0302 clinical medicine, metabolism [Endoplasmic Reticulum], Homeostasis, metabolism [Calcium], metabolism [Spermatids], 0303 health sciences, biology, Chemistry, Articles, metabolism [Aspartic Acid Endopeptidases], Transmembrane protein, Cell biology, Phospholamban, medicine.anatomical_structure, Organ Specificity, Female, Signal peptide peptidase, Germ cell, Proteases, endocrine system, metabolism [Germ Cells], Intramembrane protease, enzymology [Testis], 03 medical and health sciences, ddc:570, Genetics, medicine, Animals, Humans, chemistry [Membrane Proteins], Amino Acid Sequence, ddc:610, Molecular Biology, 030304 developmental biology, chemistry [Aspartic Acid Endopeptidases], Protease, enzymology [Cell Membrane], Endoplasmic reticulum, metabolism [Calcium-Binding Proteins], HEK293 Cells, biology.protein, 030217 neurology & neurosurgery, metabolism [Membrane Proteins], HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1418b4ad477efe0f728a4ddd7233c8b6Test
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/51759Test

المؤلفون: Ronny Heidasch, Karsten Richter, Michelle Neßling, Holger Lorenz, Nicole S. Malchus, Marius K. Lemberg, Dönem Avci

المصدر: The Journal of biological chemistry. 294(8)

مصطلحات موضوعية: 0301 basic medicine, Proteomics, Intramembrane protease, Golgi Apparatus, Endoplasmic Reticulum, Biochemistry, 03 medical and health sciences, symbols.namesake, Lipid biosynthesis, Protein biosynthesis, Aspartic Acid Endopeptidases, Humans, Molecular Biology, Secretory pathway, Organelles, 030102 biochemistry & molecular biology, biology, Chemistry, Qa-SNARE Proteins, Endoplasmic reticulum, Endoplasmic Reticulum-Associated Degradation, Cell Biology, Golgi apparatus, Cell biology, 030104 developmental biology, HEK293 Cells, Membrane protein, Proteolysis, symbols, biology.protein, Signal peptide peptidase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::189f74460303004cf08b6093f56920ceTest
https://pubmed.ncbi.nlm.nih.gov/30578301Test

المؤلفون: Sara Suna Yucel, Manfred Wozny, Alessandra Lorenzoni, Walter Stelzer, Dieter Langosch, Marius K. Lemberg

المصدر: Cell Reports, Vol 26, Iss 11, Pp 3087-3099.e11 (2019)

مصطلحات موضوعية: X-Box Binding Protein 1, 0301 basic medicine, XBP1, Endoplasmic-reticulum-associated protein degradation, Endoplasmic Reticulum, Regulated Intramembrane Proteolysis, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, Aspartic Acid Endopeptidases, Humans, Peptide bond, lcsh:QH301-705.5, biology, Chemistry, Endoplasmic reticulum, Active site, Intracellular Membranes, Transmembrane protein, ddc, Transmembrane domain, HEK293 Cells, 030104 developmental biology, lcsh:Biology (General), Mutation, Proteolysis, biology.protein, Unfolded protein response, Biophysics, Signal peptide peptidase, Heme Oxygenase-1, SEC Translocation Channels, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ccf463579e8bdf2ef990583726d994Test

المؤلفون: Mark Russell, Norkhairin Yusuf, Noel G. Morgan, Martin Eichmann, Sarah J. Richardson, Mark Peakman, Deborah Kronenberg-Versteeg, Peter A. van Veelen, Beate Hehn, Marius K. Lemberg, Arnoud H. de Ru

المصدر: Diabetes, 67(4), 687-696
Kronenberg-Versteeg, D, Eichmann, M, Russell, M A, de Ru, A, Hehn, B, Yusuf, N, van Veelen, P A, Richardson, S J, Morgan, N G, Lemberg, M K & Peakman, M 2018, ' Molecular Pathways for Immune Recognition of Preproinsulin Signal Peptide in Type 1 Diabetes ', Diabetes, vol. 67, no. 4, pp. 687-696 . https://doi.org/10.2337/db17-0021Test

مصطلحات موضوعية: 0301 basic medicine, Signal peptide, Preproinsulin, Endocrinology, Diabetes and Metabolism, HLA-A24 Antigen, Human leukocyte antigen, In Vitro Techniques, Protein Sorting Signals, Endoplasmic Reticulum, Aminopeptidases, Epitope, Cell Line, HLA-A11 Antigen, Minor Histocompatibility Antigens, Epitopes, Gene Knockout Techniques, 03 medical and health sciences, Risk Factors, HLA-A2 Antigen, Internal Medicine, Aspartic Acid Endopeptidases, Humans, Insulin, Genetic Predisposition to Disease, Protein Precursors, HLA-A Antigens, Chemistry, Antigen processing, Endoplasmic reticulum, Transporter associated with antigen processing, Protective Factors, Cell biology, Protein Transport, Diabetes Mellitus, Type 1, 030104 developmental biology, HLA-B Antigens, Signal peptide peptidase, T-Lymphocytes, Cytotoxic

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d873924642ea5d31f0268e7d9e0658b6Test
https://doi.org/10.2337/db17-0021Test

المؤلفون: Bianca Schrul, Dönem Avci, Oliver Schilling, Maya Schuldiner, Akio Fukumori, Elisabeth Kremmer, Marius K. Lemberg, Chia-yi Chen, Michal Breker, Harald Steiner, Martin L. Biniossek, Idan Frumkin, Shai Fuchs

المصدر: Mol. Cell 56, 630-640 (2014)
Molecular cell 56(5), 630-640 (2014). doi:10.1016/j.molcel.2014.10.012

مصطلحات موضوعية: metabolism [Peptide Hydrolases], Endoplasmic Reticulum, 0302 clinical medicine, metabolism [Endoplasmic Reticulum], Gene Expression Regulation, Fungal, metabolism [Membrane Transport Proteins], physiology [Saccharomyces cerevisiae], Phylogeny, 0303 health sciences, enzymology [Saccharomyces cerevisiae], Endoplasmic Reticulum-Associated Degradation, metabolism [Zinc], Cell biology, SSM4 protein, S cerevisiae, Zinc, Biochemistry, Ypf1 protein, S cerevisiae, Signal peptide peptidase, genetics [Peptide Hydrolases], Proteases, Saccharomyces cerevisiae Proteins, Intramembrane protease, Ubiquitin-Protein Ligases, Saccharomyces cerevisiae, macromolecular substances, Nutrient sensing, Endoplasmic-reticulum-associated protein degradation, Biology, metabolism [Cell Membrane], Presenilin, 03 medical and health sciences, metabolism [Ubiquitin-Protein Ligases], ERAD pathway, ddc:610, genetics [Saccharomyces cerevisiae Proteins], Molecular Biology, 030304 developmental biology, Endoplasmic reticulum, Cell Membrane, Dfm1 protein, S cerevisiae, Membrane Proteins, Membrane Transport Proteins, Cell Biology, metabolism [Saccharomyces cerevisiae Proteins], biology.protein, Sequence Alignment, metabolism [Membrane Proteins], 030217 neurology & neurosurgery, Peptide Hydrolases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66714995f0d6599f2e25ab6d2987cd3Test

المؤلفون: Dönem Avci, Beate Hehn, Chia-yi Chen, Dieter Langosch, Nicole S. Malchus, Marius K. Lemberg, Walter Stelzer

المصدر: The EMBO Journal. 33:2492-2506

مصطلحات موضوعية: X-Box Binding Protein 1, Signal peptide, Proteasome Endopeptidase Complex, Receptors, Cell Surface, Regulatory Factor X Transcription Factors, Endoplasmic-reticulum-associated protein degradation, General Biochemistry, Genetics and Molecular Biology, Humans, Molecular Biology, General Immunology and Microbiology, biology, General Neuroscience, Endoplasmic reticulum, Serine Endopeptidases, Membrane Proteins, Endoplasmic Reticulum-Associated Degradation, Articles, Cell biology, Ubiquitin ligase, DNA-Binding Proteins, HEK293 Cells, Biochemistry, Ectodomain, Proteolysis, Unfolded protein response, biology.protein, Signal peptide peptidase, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57246d751801f7cafd46142eb345310eTest
https://doi.org/10.15252/embj.201488208Test

المؤلفون: Marius K. Lemberg

المصدر: Traffic. 12:1109-1118

مصطلحات موضوعية: Proteases, Endosome, Growth factor, medicine.medical_treatment, Cell Membrane, PARL, Membrane Proteins, Cell Biology, Biology, Biochemistry, Regulated Intramembrane Proteolysis, Presenilin, Cell biology, Fungal Proteins, Protein Transport, Structural Biology, Proteolysis, Mitophagy, Genetics, medicine, Humans, Molecular Biology, Signal peptide peptidase, Peptide Hydrolases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d023c8b45a737aca4c6a4bb9012510Test
https://doi.org/10.1111/j.1600-0854.2011.01219.xTest