دورية أكاديمية

Synthesis of Water-Soluble Red-Emitting Thienyl–BODIPYs and Bovine Serum Albumin Labeling.

التفاصيل البيبلوغرافية
العنوان: Synthesis of Water-Soluble Red-Emitting Thienyl–BODIPYs and Bovine Serum Albumin Labeling.
المؤلفون: Poirel, Arnaud, Retailleau, Pascal, De Nicola, Antoinette, Ziessel, Raymond
المصدر: Chemistry - A European Journal; 1/27/2014, Vol. 20 Issue 5, p1252-1189, 6p
مصطلحات موضوعية: THIENYL compounds, SERUM albumin, GALACTOSYLCERAMIDES, METHYL ether, BIOMOLECULES
مستخلص: Thesynthesis of three red-emitting and watersoluble thienyl-BODIPYs has beenachieved. The trimethyl- (propargyl)ammonium group was chosen as a vector forwater solubility. One or two cationic arms were introduced either on the2-position of the thienyl unit or on the 4-position on the boron atom. Thesedyes have pronounced absorption around 600 nm and intense emission at 650 nmwith quantum yield of about 60% in water. Grafting of such BODIPYs via a flexible arm to BSA is veryefficient, allowing attachment of 1 to 30 labels in a controlled manner. Very strong fluorescence (quantum yield 56%)without aggregation of the dye at a low loading ratio (1:5 BSA/label) in PBSbuffer is measured. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:09476539
DOI:10.1002/chem.201303988