المؤلفون: Chen, Liang, Chen, Jia-Yu, Huang, Yi-Jou, Gu, Ying, Qiu, Jinsong, Qian, Hao, Shao, Changwei, Zhang, Xuan, Hu, Jing, Li, Hairi, He, Shunmin, Zhou, Yu, Abdel-Wahab, Omar, Zhang, Dong-Er, Fu, Xiang-Dong

المصدر: Molecular Cell. 69(3)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Rare Diseases, Genetics, Hematology, Aetiology, 2.1 Biological and endogenous factors, Generic health relevance, Base Sequence, Cell Cycle Checkpoints, HEK293 Cells, Humans, Mutation, Myelodysplastic Syndromes, Nuclear Proteins, Phosphoproteins, RNA Splicing, RNA Splicing Factors, Ribonucleoproteins, Serine-Arginine Splicing Factors, Splicing Factor U2AF, MDS, R-loops, genome instability, splicing factor mutations, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8zw3p8z1Test

المؤلفون: Qiu, Jinsong, Zhou, Bing, Thol, Felicitas, Zhou, Yu, Chen, Liang, Shao, Changwei, DeBoever, Christopher, Hou, Jiayi, Li, Hairi, Chaturvedi, Anuhar, Ganser, Arnold, Heuser, Michael, Bejar, Rafael, Zhang, Dong-Er, Fu, Xiang-Dong

المصدر: RNA. 22(10)

مصطلحات موضوعية: RASL-seq, diagnostic and prognostic splicing signatures, myelodysplastic syndromes (MDS), pre-mRNA splicing, splicing factor mutations, Adult, Aged, Aged, 80 and over, Case-Control Studies, Female, Humans, Male, Middle Aged, Mutation, Myelodysplastic Syndromes, Phosphoproteins, RNA Splice Sites, RNA Splicing, RNA Splicing Factors, Serine-Arginine Splicing Factors, Splicing Factor U2AF

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4db5c436Test

المؤلفون: Simpson Joseph, Tapan Biswas, Gourisankar Ghosh, Kaushik Saha, Mike Minh Fernandez

المصدر: Nucleic Acids Research

مصطلحات موضوعية: Scaffold, AcademicSubjects/SCI00010, RNA Splicing, Computational biology, Biology, medicine.disease_cause, Ribonucleoprotein, U1 Small Nuclear, Exon, Protein Domains, RNA and RNA-protein complexes, RNA Precursors, Genetics, medicine, Humans, splice, snRNP, RNA, Messenger, Mutation, Serine-Arginine Splicing Factors, Intron, Splicing Factor U2AF, Introns, RNA splicing, Nucleic Acid Conformation, RNA Splice Sites, Precursor mRNA, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce59e2c3698e70358ca292d9ee7dfedTest
https://doi.org/10.1093/nar/gkab533Test

المؤلفون: Musa Yilmaz, Hagop M. Kantarjian, Gautam Borthakur, Maro Ohanian, Kelly S. Chien, Koji Sasaki, Abhishek Maiti, Koichi Takahashi, Nicholas J. Short, Naveen Pemmaraju, Guillermo Montalban-Bravo, Curtis Lachowiez, Sherry Pierce, Farhad Ravandi, Marina Konopleva, Ken Furudate, Keyur P. Patel, Elias Jabbour, Naval Daver, Tapan M. Kadia, Sanam Loghavi, Yesid Alvarado, Guillermo Garcia-Manero, Courtney D. DiNardo

المصدر: Blood Adv

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Spliceosome, medicine.disease_cause, IDH2, chemistry.chemical_compound, Internal medicine, Humans, Medicine, Secondary Acute Myeloid Leukemia, Retrospective Studies, Sulfonamides, Mutation, Myeloid Neoplasia, Serine-Arginine Splicing Factors, Venetoclax, business.industry, Nuclear Proteins, Cancer, Myeloid leukemia, Retrospective cohort study, Hematology, Bridged Bicyclo Compounds, Heterocyclic, Splicing Factor U2AF, medicine.disease, Leukemia, Myeloid, Acute, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed2c73917d3bec2859b7f1838ccef3dTest
https://doi.org/10.1182/bloodadvances.2020004173Test

المؤلفون: Aslan, Derya, Garde, Christian, Nygaard, Mette Katrine, Helbo, Alexandra Søgaard, Dimopoulos, Konstantinos, Hansen, Jakob Werner, Severinsen, Marianne Tang, Treppendahl, Marianne Bach, Sjø, Lene Dissing, Grønbæk, Kirsten, Sommer Kristensen, Lasse

المصدر: Aslan , D , Garde , C , Nygaard , M K , Helbo , A S , Dimopoulos , K , Hansen , J W , Severinsen , M T , Treppendahl , M B , Sjø , L D , Grønbæk , K & Sommer Kristensen , L 2016 , ' Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations ' , OncoTarget , vol. 7 , no. 9 , pp. 9951-63 . https://doi.org/10.18632/oncotarget.7127Test

مصطلحات موضوعية: Aged, 80 and over, Alternative Splicing, Cluster Analysis, Cohort Studies, DNA Mutational Analysis, Down-Regulation, Female, Gene Expression Profiling, Genes, Tumor Suppressor, Humans, Male, MicroRNAs, Middle Aged, Mutation, Myelodysplastic Syndromes, Phosphoproteins, RNA Splicing Factors, Reverse Transcriptase Polymerase Chain Reaction, Serine-Arginine Splicing Factors, Spliceosomes, Splicing Factor U2AF, Journal Article, Research Support, Non-U.S. Gov't

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.18632/oncotarget.7127Test
https://curis.ku.dk/portal/da/publications/tumor-suppressor-micrornas-are-downregulated-in-myelodysplastic-syndrome-with-spliceosome-mutationsTest(47ec934b-3d4a-4ad9-8bb4-9e2231e4568b).html
https://curis.ku.dk/ws/files/187629517/7127_108207_3_PB.pdfTest

المؤلفون: Aarif M. N. Batcha, Tobias Herold, Stefan K. Bohlander, Dennis Görlich, Bianka Ksienzyk, Wolfgang E. Berdel, Jan Braess, Wolfgang Hiddemann, Alexander Graf, Ulrich Mansmann, Stephanie Schneider, Maria Cristina Sauerland, Bernhard J. Woermann, Karsten Spiekermann, Stefan Krebs, Hanna Janke, Nikola P. Konstandin, Vindi Jurinovic, Julia Philippou-Massier, Klaus H. Metzeler, Stefan Canzar, Maja Rothenberg-Thurley, Stefanos A. Bamopoulos, Helmut Blum

المصدر: Leukemia 34, 2621–2634 (2020)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Gene isoform, Cancer Research, Myeloid, Adolescent, RNA Splicing, Mutant, Biology, medicine.disease_cause, Cohort Studies, Young Adult, 03 medical and health sciences, Splicing factor, 0302 clinical medicine, medicine, Humans, Gene, Aged, Aged, 80 and over, Mutation, Serine-Arginine Splicing Factors, Myeloid leukemia, Hematology, Middle Aged, Phosphoproteins, Splicing Factor U2AF, medicine.disease, Haematopoiesis, Leukemia, Myeloid, Acute, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, RNA splicing, Cancer research, Female, RNA Splicing Factors, Myeloid leukaemia

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4b31530b59e4faf05a198628ca8ad1aTest
https://doi.org/10.1038/s41375-020-0839-4Test

المساهمون: JUNG YONG HONG, JA-YOUNG SEO, SUN-HEE KIM, HYUN AE JUNG, SILVIA PARK, KIHYUN KIM, CHUL WON JUNG, JIN SEOK KIM, JOON SEONG PARK, HEE-JIN KIM, JUN HO JANG, Kim, Jin Seok

مصطلحات موضوعية: Adult, Aged, 80 and over, Azacitidine/administration & dosage, Azacitidine/analogs & derivatives, Female, Humans, Male, Middle Aged, Mutation, Myelodysplastic Syndromes/drug therapy, Myelodysplastic Syndromes/genetics, Myelodysplastic Syndromes/pathology, Nuclear Proteins/genetics, Prognosis, RNA Splicing/genetics, Ribonucleoproteins/genetics, Serine-Arginine Splicing Factors, Spliceosomes/drug effects, Spliceosomes/genetics, Splicing Factor U2AF, Treatment Outcome, Myelodysplastic syndrome, SRSF2, U2AF1, ZRSR2, decitabine

وصف الملف: application/pdf

العلاقة: ANTICANCER RESEARCH; J00188; OAK-9999-20070; https://ir.ymlib.yonsei.ac.kr/handle/22282913/165809Test; T999901267; ANTICANCER RESEARCH, Vol.35(5) : 3081-3089, 2015

الإتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/165809Test

المؤلفون: Malgorzata Olszewska, Eirini P. Papapetrou, Julie Teruya-Feldstein, Andriana G. Kotini, Shailee Vora, Ernesto Guccione, Emily C. Wheeler, Daniel Mayer, Roger K. Sunahara, Gene W. Yeo, Lewis B. Silverman, Samuel S. Park

المصدر: Cancer Discov

مصطلحات موضوعية: MAPK/ERK pathway, RNA Splicing, Biology, medicine.disease_cause, Article, Splicing factor, Neoplasms, medicine, GNAS complex locus, Chromogranins, GTP-Binding Protein alpha Subunits, Gs, Humans, Induced pluripotent stem cell, G alpha subunit, Mitogen-Activated Protein Kinase Kinases, Serine-Arginine Splicing Factors, Alternative splicing, Splicing Factor U2AF, Cell biology, Alternative Splicing, Oncology, Myelodysplastic Syndromes, RNA splicing, Mutation, biology.protein, RNA, RNA Splicing Factors, Carcinogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77bc381bfac4a0dd76ca5816698440bTest
https://pubmed.ncbi.nlm.nih.gov/34620690Test

المؤلفون: Antonio González, Chary López-Pedrera, Mª Angeles Aguirre, Raúl M. Luque, Rafaela Ortega Castro, Eduardo Collantes-Estevez, Nuria Barbarroja, Iván Arias de la Rosa, Carlos Perez-Sanchez, J. Calvo, A. M. Patiño-Trives, Carmen Conde, Alejandro Escudero-Contreras, M. D. C. Abalos-Aguilera, María Luque-Tévar, Mercedes del Rio-Moreno, Justo P Castano-Fuentes, Ricardo Blazquez-Encinas, P. Segui, Pilar Font, Cristóbal Román-Rodríguez, Sergio Pedraza-Arevalo, Alejandro Ibáñez-Costa

المصدر: Annals of the Rheumatic Diseases

مصطلحات موضوعية: Male, Neutrophils, tumor necrosis factor inhibitors, Fc receptor, Gene Expression, Cell Cycle Proteins, Anti-Citrullinated Protein Antibodies, Monocytes, Arthritis, Rheumatoid, Mice, RNA, Small Nuclear, Synovial Fluid, Immunology and Allergy, Lymphocytes, Cells, Cultured, biology, Serine-Arginine Splicing Factors, Anti–citrullinated protein antibody, RNA-Binding Proteins, Middle Aged, Ribonucleoproteins, Small Nuclear, DNA-Binding Proteins, biological therapy, Rheumatoid arthritis, Antirheumatic Agents, Cytokines, Tumor necrosis factor alpha, Female, RNA Splicing Factors, medicine.symptom, Antibody, Adult, Immunology, Inflammation, Rheumatoid Arthritis, General Biochemistry, Genetics and Molecular Biology, Proinflammatory cytokine, Ribonucleoprotein, U1 Small Nuclear, Rheumatology, medicine, Synovial fluid, Animals, Humans, Adaptor Proteins, Signal Transducing, business.industry, Sequence Analysis, RNA, Tumor Necrosis Factor-alpha, medicine.disease, Splicing Factor U2AF, Repressor Proteins, Alternative Splicing, Case-Control Studies, biology.protein, Spliceosomes, RNA, Citrullination, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::345600a50c9c5f519d921136317c6388Test
https://pubmed.ncbi.nlm.nih.gov/34625402Test

المؤلفون: Curtis A. Hanson, Ayalew Tefferi, Christy Finke, Terra L. Lasho, Domenico Penna, Animesh Pardanani, Rangit Vallapureddy, Naseema Gangat, Rhett P. Ketterling

المصدر: American Journal of Hematology. 94:286-290

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Logistic regression, Gastroenterology, Hemoglobins, Leukocyte Count, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Bone Marrow, Risk Factors, Internal medicine, Overall survival, Humans, Medicine, Longitudinal Studies, Survivors, Genetic risk, Myelofibrosis, Survival analysis, Prognostic models, Aged, Aged, 80 and over, Serine-Arginine Splicing Factors, Platelet Count, business.industry, Age Factors, Female sex, Hematology, Middle Aged, Prognosis, Splicing Factor U2AF, medicine.disease, Survival Analysis, Repressor Proteins, Logistic Models, Phenotype, Circulating Blasts, Primary Myelofibrosis, 030220 oncology & carcinogenesis, Mutation, Female, Calreticulin, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba935f710117bb93aff57a422b811f7Test
https://doi.org/10.1002/ajh.25351Test