التفاصيل البيبلوغرافية
| العنوان: |
Dwell time and risk of central-line-associated bloodstream infection in neonates |
| المؤلفون: |
Sanderson, E, Yeo, KT, Wang, AY, Callander, I, Bajuk, B, Bolisetty, S, Lui, K, Bowen, J, Sedgley, S, Carlisle, H, Kent, A, Smith, J, Craven, P, Cruden, L, Argomand, A, Rieger, I, Malcolm, G, Lutz, T, Reid, S, Stack, J, Medlin, K, Marcin, K, Shingde, V, Chin, MF, Bonzer, K, Badawi, N, Halliday, R, Karskens, C, Paradisis, M, Kluckow, M, Jacobs, C, Numa, A, Williams, G, Young, J, Luig, M, Baird, J, Oei, JL, Cameron, D |
| سنة النشر: |
2017 |
| المجموعة: |
University of Technology Sydney: OPUS - Open Publications of UTS Scholars |
| مصطلحات موضوعية: |
Epidemiology, Humans, Sepsis, Catheterization, Central Venous, Incidence, Risk Assessment, Retrospective Studies, Prospective Studies, Time Factors, Infant, Newborn, Female, Male, Catheter-Related Infections |
| الوصف: |
© 2017 The Healthcare Infection Society Background Umbilical venous catheters (UVCs) or peripherally inserted central catheters (PICCs), widely used in high-risk neonates, may have a threshold dwell time for subsequent increased risk of central-line-associated bloodstream infection (CLABSI). Aim To evaluate the CLABSI risks in neonates having either UVC, PICC, or those having both sequentially. Methods The study included 3985 infants who had UVC or PICC inserted between 2007 and 2009 cared for in 10 regional neonatal intensive care units: 1392 having UVC only (group 1), 1317 PICC only (group 2), and 1276 both UVC and PICC (group 3). Findings There were 403 CLABSIs among 6000 venous catheters inserted, totalling 43,302 catheter-days. CLABSI rates were higher in group 3 infants who were of lowest gestation (16.9 per 1000 UVC-days and 12.5 per 1000 PICC-days; median: 28 weeks) when compared with group 1 (3.3 per 1000 UVC-days; 37 weeks) and group 2 (4.8 per 1000 PICC-days; 30 weeks). Life table and Kaplan–Meier hazard analysis showed that UVC CLABSI rate increased stepwise to 42 per 1000 UVC-days by day 10, with the highest rate in group 3 (85 per 1000 UVC-days). PICC CLABSI rates remained relatively stable at 12–20 per 1000 PICC-days. Compared to PICC, UVC had a higher adjusted CLABSI risk controlled for dwell time. Among group 3, replacing UVC electively before day 4 may have a trend of lower CLABSI risk than late replacement. Conclusion There was no cut-off duration beyond which PICC should be removed electively. Early UVC removal and replacement by PICC before day 4 might be considered. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
unknown |
| تدمد: |
0195-6701 |
| العلاقة: |
Journal of Hospital Infection; Journal of Hospital Infection, 2017, 97 (3), pp. 267 - 274; http://hdl.handle.net/10453/124269Test |
| الإتاحة: |
http://hdl.handle.net/10453/124269Test |
| رقم الانضمام: |
edsbas.59791CD1 |
| قاعدة البيانات: |
BASE |
