دورية أكاديمية
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-alpha and-gamma via IRF1 induction.
| العنوان: | PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-alpha and-gamma via IRF1 induction. |
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| المؤلفون: | Colli, Maikel Luis, Hill, Jessica L E, Marroquí, Laura, Chaffey, Jessica, Dos Santos, Reinaldo Sousa, Leete, Pia, Coomans De Brachene, Alexandra, Paula, Flavia M M, Op De Beeck, Anne, Castela, Angela, Marselli, Lorella, Krogvold, Lars, Dahl-Jorgensen, Knut, Marchetti, Piero, Morgan, Noel G, Richardson, Sarah J, Eizirik, Decio L. |
| المصدر: | EBioMedicine, 36 |
| سنة النشر: | 2018 |
| المجموعة: | DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB) |
| مصطلحات موضوعية: | Sciences bio-médicales et agricoles, CD274, IRF1, Immune checkpoint inhibitor, PDL-1, PDL1, Pancreatic beta cells, Pancreatic islets, Type 1 diabetes |
| الوصف: | Antibodies targeting PD-1 and its ligand PDL1 are used in cancer immunotherapy but may lead to autoimmune diseases, including type 1 diabetes (T1D). It remains unclear whether PDL1 is expressed in pancreatic islets of people with T1D and how is it regulated. ; “Innovative Medicines Initiative 2”;“European Union(EU)”“Horizon2020”; and EFPIA”,“JDRF International” and The Leona M.and Harry B.Helmsley Charitable Trust”; ; SCOPUS: ar.j ; info:eu-repo/semantics/published |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 2 full-text file(s): application/pdf | application/pdf |
| اللغة: | English |
| العلاقة: | uri/info:doi/10.1016/j.ebiom.2018.09.040; uri/info:pii/S2352-3964(18)30398-0; uri/info:pmid/30269996; uri/info:scp/85054193057; uri/info:bibcode/innodia; uri/info:sici/30269996; https://dipot.ulb.ac.be/dspace/bitstream/2013/277638/5/main.pdfTest; https://dipot.ulb.ac.be/dspace/bitstream/2013/277638/6/doi_261265.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/277638Test |
| الإتاحة: | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/277638Test https://dipot.ulb.ac.be/dspace/bitstream/2013/277638/5/main.pdfTest |
| رقم الانضمام: | edsbas.D8EDE8DB |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |