المؤلفون: Brandon Wey-Hung Liauw, Arash Foroutan, Michael R Schamber, Weifeng Lu, Hamid Samareh Afsari, Reza Vafabakhsh

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: GPCRs, conformational dynamics, allosteric modulation, single-molecule FRET, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/78982Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/d2da857e68904c2194a080f8c88cfbf1Test

المؤلفون: Cathrine Bergh, Stephanie A Heusser, Rebecca Howard, Erik Lindahl

المصدر: eLife, Vol 10 (2021)

مصطلحات موضوعية: ligand-gated ion channel, gating, allosteric modulation, molecular dynamics, electrophysiology, markov state model, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/68369Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/8d7ef17dfa724cc3afa78e5417a615beTest

المؤلفون: Marijke Brams, Cedric Govaerts, Kumiko Kambara, Kerry L Price, Radovan Spurny, Anant Gharpure, Els Pardon, Genevieve L Evans, Daniel Bertrand, Sarah CR Lummis, Ryan E Hibbs, Jan Steyaert, Chris Ulens

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: ligand-gated ion channels, structural biology, allosteric modulation, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/51511Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/342cb67467c141c1a4b0ebacf9821115Test

المؤلفون: Pablo Miranda, Miguel Holmgren, Teresa Giraldez

المصدر: eLife, Vol 7 (2018)

مصطلحات موضوعية: ion channels, allosteric modulation, BK, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/40664Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/7b1b342f0f334b4dada32ac647d12595Test

المؤلفون: Joan Font, Marc López-Cano, Serena Notartomaso, Pamela Scarselli, Paola Di Pietro, Roger Bresolí-Obach, Giuseppe Battaglia, Fanny Malhaire, Xavier Rovira, Juanlo Catena, Jesús Giraldo, Jean-Philippe Pin, Víctor Fernández-Dueñas, Cyril Goudet, Santi Nonell, Ferdinando Nicoletti, Amadeu Llebaria, Francisco Ciruela

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: analgesia, optopharmacology, pain neuraxis, mGlu5 receptor, allosteric modulation, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/23545Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/204af3c7e82a4250a352bd8ccbee7236Test

المؤلفون: Sandip Basak, Nicolaus Schmandt, Yvonne Gicheru, Sudha Chakrapani

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: Cys-loop receptors, allosteric modulation, nanodiscs, site-directed spin labeling, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/23886Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/4aa95d1bf8d546ed855693c2a807034aTest

المؤلفون: Swapna Bhagwanth, Ram K. Mishra, Rodney L. Johnson

المصدر: Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 204-214 (2013)

مصطلحات موضوعية: allosteric modulation, dopamine D2 receptor, peptidomimetic, Pro-Leu-Gly-NH2, spiro-bicyclic scaffold, Science, Organic chemistry, QD241-441

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1860-5397Test

الوصول الحر: https://doaj.org/article/b6594288ac8d4f60807a3974fc842d42Test

المؤلفون: Rabindra V Shivnaraine, Brendan Kelly, Krishana S Sankar, Dar'ya S Redka, Yi Rang Han, Fei Huang, Gwendolynne Elmslie, Daniel Pinto, Yuchong Li, Jonathan V Rocheleau, Claudiu C Gradinaru, John Ellis, James W Wells

المصدر: eLife, Vol 5 (2016)

مصطلحات موضوعية: GPCR, allosteric modulation, molecular dynamics, muscarinic, FRET, oligomer, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/11685Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/17c6b3b823e040f9bcdf399421d9bf20Test

المؤلفون: Bergh, Cathrine, Heusser, Stephanie, Howard, Rebecca, Lindahl, Erik

المصدر: eLife
eLife, Vol 10 (2021)
Bergh, C, Heusser, S A, Howard, R & Lindahl, E 2021, ' Markov state models of proton-and pore-dependent activation in a pentameric ligand-gated ion channel ', eLife, vol. 10, 68369 . https://doi.org/10.7554/eLife.68369Test

مصطلحات موضوعية: STRUCTURAL BASIS, MECHANISM, CONFORMATIONAL TRANSITIONS, QH301-705.5, Science, Structural Biology and Molecular Biophysics, Xenopus, ACETYLCHOLINE-RECEPTOR, DESENSITIZATION, Xenopus laevis, Animals, KINETIC-PROPERTIES, Biology (General), ligand-gated ion channel, allosteric modulation, Ligand-Gated Ion Channels, electrophysiology, Markov Chains, molecular dynamics, NICOTINIC RECEPTOR, OPEN PROBABILITY, MOLECULAR-DYNAMICS, GLOEOBACTER-VIOLACEUS, gating, markov state model, Nuclear Pore, Medicine, Protons, Research Article, Computational and Systems Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ecfeb8c67e95a09c6ed2aa865ab534dTest

المؤلفون: Chris Ulens, Els Pardon, Genevieve L. Evans, D. Bertrand, Kumiko Kambara, Jan Steyaert, Radovan Spurny, Cédric Govaerts, Marijke Brams, Kerry L. Price, Sarah C. R. Lummis, Ryan E. Hibbs, Anant Gharpure

المساهمون: Department of Bio-engineering Sciences, Structural Biology Brussels, Gharpure, Anant [0000-0002-4458-359X], Evans, Genevieve L [0000-0002-8612-9539], Steyaert, Jan [0000-0002-3825-874X], Ulens, Chris [0000-0002-8202-5281], Apollo - University of Cambridge Repository

المصدر: eLife, 9
eLife, Vol 9 (2020)

مصطلحات موضوعية: Life Sciences & Biomedicine - Other Topics, Models, Molecular, Protein Conformation, ligand-gated ion channels, ACTIVATION, neuroscience, 0302 clinical medicine, Immunologie, GATING MECHANISM, structural biology, CRYSTAL-STRUCTURE, Biology (General), 0303 health sciences, allosteric modulation, Chemistry, General Neuroscience, General Medicine, Sciences bio-médicales et agricoles, Small molecule, Medicine, Ligand-gated ion channel, Synaptic signaling, Life Sciences & Biomedicine, STRUCTURAL BASIS, Allosteric modulator, QH301-705.5, Science, Allosteric regulation, ALLOSTERIC BINDING-SITE, General Biochemistry, Genetics and Molecular Biology, Neurotransmitter binding, 03 medical and health sciences, Bacterial Proteins, molecular biophysics, NICOTINIC ACETYLCHOLINE-RECEPTOR, human, Binding site, Biology, Ion channel, 030304 developmental biology, Science & Technology, COMPLEX, Binding Sites, General Immunology and Microbiology, Neurosciences cognitives, Single-Domain Antibodies, EXTRACELLULAR DOMAIN, Mutagenesis, Site-Directed, Biophysics, Erwinia, CHIMERA, Receptors, Serotonin, 5-HT3, Microbiologie et protistologie [bacteriol.virolog.mycolog.], X-RAY-STRUCTURE, 030217 neurology & neurosurgery

وصف الملف: 1 full-text file(s): application/pdf; application/pdf; Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f200d44ca2bed9d9f15b016115158c76Test
https://hdl.handle.net/20.500.14017/ebfd9a6c-7f5a-4ce5-b0f7-d5a8a10d56d2Test