دورية أكاديمية

Migratory Pulmonary Infiltrates in a B-Cell-Depleted COVID-19 Patient.

التفاصيل البيبلوغرافية
العنوان: Migratory Pulmonary Infiltrates in a B-Cell-Depleted COVID-19 Patient.
المؤلفون: Zhu, Wenyan, Xie, Tiange, Xu, Mengru, Chen, Ruxuan, Zhang, Ting
المصدر: Infection & Drug Resistance; Nov2023, Vol. 16, p7205-7208, 4p
مصطلحات موضوعية: SARS-CoV-2, COVID-19, CONVALESCENT plasma
مستخلص: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still rampant around the world. Immunocompromised patients are prone to have long-term infection with coronavirus disease 2019 (COVID-19). However, it is difficult to decide on an appropriate treatment for persistent SARS-CoV-2 infection.Case Presentation: We present a case of prolonged SARS-CoV-2 infection in a patient who had undergone B-cell depletion therapy. Chest computed tomography (CT) revealed notable migratory pulmonary infiltrates, and bronchoalveolar lavage fluid was positive for SARS-CoV-2 (day-120). The patient responded well to the combination treatment of antiviral medication, convalescent plasma, and corticosteroid.Conclusion: When chest CT shows migratory pulmonary infiltrates in patients with recent COVID-19, it is necessary to be alert to the possibility of persistent SARS-CoV-2 infection, especially in B-cell-depleted immunocompromised patients. Once the diagnosis is confirmed, repeated antiviral therapy and intravenous convalescent plasma should be considered. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:11786973
DOI:10.2147/IDR.S439795