المؤلفون: Tinghan Li, Yibo Wen, Hangtian Guo, Tingting Yang, Haitao Yang, Xiaoyun Ji

المصدر: Frontiers in Molecular Biosciences, Vol 8 (2022)

مصطلحات موضوعية: SARS-CoV-2, ORF6, Rae1-Nup98 complex, mRNA nuclear export, crystal structure, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fmolb.2021.813248/fullTest; https://doaj.org/toc/2296-889XTest

الوصول الحر: https://doaj.org/article/60e8afe79db94ef3a0003bc7aca6451cTest

المؤلفون: Haitao Yang, Jing Yu, Lin Han, Zhenming Jin, Lei Sun, Yinkai Duan, Chao Peng, Yao Zhao, Leike Zhang, Tian You, Jun Wang, Xiaoyan Pan, Weijuan Shang, Hangtian Guo, Xiuna Yang, Luke W. Guddat, Ying Lei, Yifang Sun, Qianying Liu, Gengfu Xiao, Yan Wu, Wenqing Xu, Zihe Rao, Xiaoyu Du, Chenghao Zhu, Kailin Yang

المصدر: Protein & Cell

مصطلحات موضوعية: Drug, medicine.drug_class, media_common.quotation_subject, medicine.medical_treatment, High-throughput screening, Drug Evaluation, Preclinical, Coronavirus Papain-Like Proteases, papain-like protease, Molecular Dynamics Simulation, Pharmacology, Crystallography, X-Ray, medicine.disease_cause, Antiviral Agents, Biochemistry, Inhibitory Concentration 50, interferon stimulating gene product 15, Interferon, Drug Discovery, medicine, Humans, Protease Inhibitors, media_common, Coronavirus, Binding Sites, Protease, drug repurposing, SARS-CoV-2, Chemistry, Drug Repositioning, Imidazoles, COVID-19, Cell Biology, YM155, ISG15, Recombinant Proteins, High-Throughput Screening Assays, Protein Structure, Tertiary, COVID-19 Drug Treatment, Drug repositioning, Mutagenesis, Site-Directed, Antiviral drug, Research Article, Naphthoquinones, Biotechnology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aef53f15a2175ea54a5a7cc9398006dTest
https://doi.org/10.1007/s13238-021-00836-9Test

المؤلفون: Tinghan Li, Yibo Wen, Hangtian Guo, Tingting Yang, Haitao Yang, Xiaoyun Ji

المصدر: Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2022)

مصطلحات موضوعية: crystal structure, QH301-705.5, SARS-CoV-2, viruses, fungi, virus diseases, Brief Research Report, ORF6, Rae1-Nup98 complex, Biochemistry, Genetics and Molecular Biology (miscellaneous), Biochemistry, body regions, mRNA nuclear export, Molecular Biosciences, Biology (General), skin and connective tissue diseases, Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::480270d9c515cf78e45ee6824a9a9c2aTest
https://pubmed.ncbi.nlm.nih.gov/35096974Test

المؤلفون: Kai Wang, Xiaojian Han, Zhe-Rui Zhang, Ailong Huang, Shuyi Song, Jie Hu, Guiji Zhang, Yan Gao, Chenjian Gu, Hong-Qing Zhang, Aishun Jin, Changlong He, Bo Zhang, Ruixin Wu, Chao Hu, Luo Li, Qian Chen, Shenglong Li, Ya-Nan Zhang, Shunhua Long, Wang Wang, Fengxia Gao, Jingjing Huang, Tingting Li, Xia Cai, Wei Xu, Na Li, Song Mu, Meiying Shen, Feiyang Luo, Wang Wei, Yanan Hao, Ni Tang, Yang Wu, Haitao Yang, Jianwei Wang, Youhua Xie, Huajun Zhang, Zhenghong Yuan, Di Qu, Fengjiang Liu, Yingming Wang, Yingyi Long, Qingzhu Gao, Hangtian Guo, Xiaoyun Ji

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications

مصطلحات موضوعية: medicine.drug_class, viruses, Science, Mutant, General Physics and Astronomy, Mice, Transgenic, Antibodies, Viral, medicine.disease_cause, Monoclonal antibody, Article, Antibodies, General Biochemistry, Genetics and Molecular Biology, Epitope, Virus, Epitopes, Mice, Weight Loss, medicine, Animals, Humans, Potency, Binding site, Mutation, Binding Sites, Multidisciplinary, biology, SARS-CoV-2, Antibodies, Monoclonal, COVID-19, General Chemistry, Viral Load, Antibodies, Neutralizing, Virology, Spike Glycoprotein, Coronavirus, biology.protein, Antibody

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26c7cb30509a10291eabe4583c87f25Test
https://doi.org/10.1038/s41467-021-26539-7Test

المؤلفون: Tinghan Li (3692896), Yibo Wen (11936171), Hangtian Guo (11936174), Tingting Yang (166111), Haitao Yang (275233), Xiaoyun Ji (11835616)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, SARS-CoV-2, ORF6, Rae1-Nup98 complex, mRNA nuclear export, crystal structure

العلاقة: https://figshare.com/articles/dataset/DataSheet3_Molecular_Mechanism_of_SARS-CoVs_Orf6_Targeting_the_Rae1_Nup98_Complex_to_Compete_With_mRNA_Nuclear_Export_docx/18230993Test

الإتاحة: https://doi.org/10.3389/fmolb.2021.813248.s003Test

المؤلفون: Tinghan Li, Yibo Wen, Hangtian Guo, Tingting Yang, Haitao Yang, Xiaoyun Ji

مصطلحات موضوعية: Biochemistry, Molecular Biology, Structural Biology, Enzymes, Protein Trafficking, Proteomics and Intermolecular Interactions (excl. Medical Proteomics), Receptors and Membrane Biology, Signal Transduction, Structural Biology (incl. Macromolecular Modelling), Synthetic Biology, SARS-CoV-2, ORF6, Rae1-Nup98 complex, mRNA nuclear export, crystal structure

العلاقة: https://figshare.com/articles/dataset/DataSheet2_Molecular_Mechanism_of_SARS-CoVs_Orf6_Targeting_the_Rae1_Nup98_Complex_to_Compete_With_mRNA_Nuclear_Export_PDF/18230990Test

الإتاحة: https://doi.org/10.3389/fmolb.2021.813248.s002Test
https://figshare.com/articles/dataset/DataSheet2_Molecular_Mechanism_of_SARS-CoVs_Orf6_Targeting_the_Rae1_Nup98_Complex_to_Compete_With_mRNA_Nuclear_Export_PDF/18230990Test

المؤلفون: Hangtian Guo, Yan Gao, Tinghan Li, Tingting Li, Yuchi Lu, Le Zheng, Yue Liu, Tingting Yang, Feiyang Luo, Shuyi Song, Wei Wang, Xiuna Yang, Henry C. Nguyen, Hongkai Zhang, Ailong Huang, Aishun Jin, Haitao Yang, Zihe Rao, Xiaoyun Ji

المصدر: Cell Reports. 39:110770

مصطلحات موضوعية: Immunoglobulin Fab Fragments, SARS-CoV-2, Cryoelectron Microscopy, Spike Glycoprotein, Coronavirus, COVID-19, Humans, Angiotensin-Converting Enzyme 2, Antibodies, Viral, Antibodies, Neutralizing, General Biochemistry, Genetics and Molecular Biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da7d3f9afad32b4d155e94b7ff60218Test
https://doi.org/10.1016/j.celrep.2022.110770Test