المؤلفون: Zhang, Martin Jinye, Hou, Kangcheng, Dey, Kushal K, Sakaue, Saori, Jagadeesh, Karthik A, Weinand, Kathryn, Taychameekiatchai, Aris, Rao, Poorvi, Pisco, Angela Oliveira, Zou, James, Wang, Bruce, Gandal, Michael, Raychaudhuri, Soumya, Pasaniuc, Bogdan, Price, Alkes L

المصدر: Nature Genetics. 54(10)

مصطلحات موضوعية: Human Genome, Genetics, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Gene Expression Profiling, Genome-Wide Association Study, Multifactorial Inheritance, RNA-Seq, Single-Cell Analysis, Triglycerides, Biological Sciences, Medical and Health Sciences, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2n72q9f0Test

المؤلفون: Smillie, Christopher S., Biton, Moshe, Ordovas-Montanes, Jose, Sullivan, Ken M., Burgin, Grace, Graham, Daniel B., Herbst, Rebecca H., Rogel, Noga, Slyper, Michel, Waldman, Julia, Sud, Malika, Andrews, Elizabeth, Velonias, Gabriella, Haber, Adam L., Jagadeesh, Karthik, Vickovic, Sanja, Yao, Junmei, Stevens, Christine, Dionne, Danielle, Nguyen, Lan T., Villani, Alexandra-Chloe, Hofree, Matan, Creasey, Elizabeth A., Huang, Hailiang, Rozenblatt-Rosen, Orit, Garber, John J., Khalili, Hamed, Desch, A. Nicole, Daly, Mark J., Ananthakrishnan, Ashwin N., Shalek, Alex K., Xavier, Ramnik J., Regev, Aviv

المساهمون: Institute for Molecular Medicine Finland, University of Helsinki

مصطلحات موضوعية: INFLAMMATORY-BOWEL-DISEASE, GENE-EXPRESSION, RNA-SEQ, DENDRITIC CELLS, T-CELLS, DATABASE, LOCI, DIFFERENTIATION, ASSOCIATION, ANTIBODIES, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: We thank all consenting participants of this study, the clinical staff at Massachusetts General Hospital, Leslie Gaffney and Anna Hupalowska for help with figures, Tim Tickle for help with the Single Cell Portal, Vijay Yajnik, Frank Colizzo, and Abdifatah Omer. M. B. was supported by a postdoctoral fellowship from the Human Frontiers Science Program. J. O.-M. is an HHMI Damon Runyon Cancer Research Foundation Fellow (DRG-2274-16). Work was supported by the Klarman Cell Observatory (to A. R. and R. J. X.); HHMI (to A. R.); the Manton Foundation (to A. R. and R. X.); Broadnext10 (to A. R. and R. J. X.); DK043351, DK114784, DK117263, the Helmsley Charitable Trust, and the Crohn's and Colitis Foundation (to R. J. X.); a Sloan Fellowship in Chemistry (to A. K. S.); the Searle Scholars Program (to A. K. S.); the Beckman Young Investigator Program (to A. K. S.); and NIH 5U24AI118672 (to A. R. and A. K. S.). This publication is part of the Human Cell Atlas.; Smillie , C S , Biton , M , Ordovas-Montanes , J , Sullivan , K M , Burgin , G , Graham , D B , Herbst , R H , Rogel , N , Slyper , M , Waldman , J , Sud , M , Andrews , E , Velonias , G , Haber , A L , Jagadeesh , K , Vickovic , S , Yao , J , Stevens , C , Dionne , D , Nguyen , L T , Villani , A-C , Hofree , M , Creasey , E A , Huang , H , Rozenblatt-Rosen , O , Garber , J J , Khalili , H , Desch , A N , Daly , M J , Ananthakrishnan , A N , Shalek , A K , Xavier , R J & Regev , A 2019 , ' Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis ' , Cell , vol. 178 , no. 3 , pp. 714-+ . https://doi.org/10.1016/j.cell.2019.06.029Test; 1f0997a2-58bd-4e9e-a0a6-a7cf896aaf82; http://hdl.handle.net/10138/320937Test; 000476973800018

الإتاحة: http://hdl.handle.net/10138/320937Test