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1دورية أكاديمية
المؤلفون: Britta Schneider, Michael Grote, Matthias John, Alexander Haas, Birgit Bramlage, Ludger M lckenstein, Kerstin Jahn-Hofmann, Frieder Bauss, Weijun Cheng, Rebecca Croasdale, Karin Daub, Simone Dill, Eike Hoffmann, Wilma Lau, Helmut Burtscher, James L Ludtke, Silke Metz, Olaf Mundigl, Zane C Neal, Werner Scheuer, Jan Stracke, Hans Herweijer, Ulrjch Brinkmann
المصدر: Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
مصطلحات موضوعية: bispecific antibody, dynamic polyconjugate, hapten, lipid nanoparticle, RNA interference, siRNA delivery, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S2162253116301032Test; https://doaj.org/toc/2162-2531Test
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المؤلفون: Darren H. Wakefield, Kerstin Jahn-Hofmann, Julia Hegge, Claudia E. Oropeza, Hans-Peter Vornlocher, Markus Hossbach, Qili Chu, David B. Rozema, Ingo Roehl, Alan McLachlan, Holly Hamilton, Philipp Hadwiger, Christine I. Wooddell, Matthias John, Jason Klein, Jochen Deckert, David L. Lewis
المصدر: Molecular Therapy
مصطلحات موضوعية: Male, Hepatitis B virus, Small interfering RNA, Acetylgalactosamine, Genotype, Biology, medicine.disease_cause, Virus, RNAi Therapeutics, Mice, Drug Delivery Systems, Hepatitis B, Chronic, RNA interference, Drug Discovery, medicine, Genetics, Animals, Humans, Amino Acid Sequence, RNA, Small Interfering, Molecular Biology, Pharmacology, Gene knockdown, Binding Sites, RNA, Genetic Therapy, Virology, Macaca fascicularis, Cholesterol, Gene Knockdown Techniques, Hepatocytes, RNA, Viral, Molecular Medicine, Original Article, Female, RNA Interference, Peptides, Viral load
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd54760eecf60d79cd46602fcf7f0c3aTest
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المؤلفون: K. Narayanannair Jayaprakash, Maria Frank-Kamenetsky, Daniel G. Anderson, Robert Langer, Yupeng Fan, Tracy Zimmermann, Muthiah Manoharan, Ingo Röhl, Kevin Fitzgerald, Timothy Racie, Martin Maier, Christina Gamba-Vitalo, Jürgen Soutschek, Akin Akinc, Norma N. Anderson, Lubomir Nechev, Pamela Tan, Muthusamy Jayaraman, Gang Wang, Philipp Hadwiger, Jay D. Horton, Klaus Charisse, Victor Koteliansky, Aldo Grefhorst, David Butler, Matthias John, Antonin de Fougerolles, Robert Dorkin, Timothy Read, Birgit Bramlage, Hans-Peter Vornlocher, Jamie Wong, Kallanthottathil G. Rajeev
المساهمون: Experimental Vascular Medicine, Vascular Medicine, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism
المصدر: Proceedings of the National Academy of Sciences of the United States of America, 105(33), 11915-11920. National Academy of Sciences
مصطلحات موضوعية: Primates, Small interfering RNA, Time Factors, Apolipoprotein B, Pharmacology, RNAi Therapeutics, Mice, chemistry.chemical_compound, RNA interference, Animals, Humans, Gene silencing, RNA, Messenger, RNA, Small Interfering, Mice, Knockout, Multidisciplinary, Molecular Structure, biology, Cholesterol, PCSK9, Serine Endopeptidases, Cholesterol, LDL, Biological Sciences, Molecular biology, Tissue LDLR levels, Rats, Liver, chemistry, LDL receptor, biology.protein, lipids (amino acids, peptides, and proteins), Plasma PCSK9
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c0eef01dd5bd57cc9c0e254fce8aa5Test
https://doi.org/10.1073/pnas.0805434105Test -
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المؤلفون: Ivanka Toudjarska, Jürgen Soutschek, Vandana Sood, Kevin McClintock, Akin Akinc, Birgit Bramlage, Matthew N. Fedoruk, Timothy Racie, Adam Judge, Ian MacLachlan, Hans-Peter Vornlocher, Lorne R. Palmer, Lloyd Jeffs, Kieu Lam, Sumi Shanmugam, William Zedalis, Tracy Zimmermann, Ingo Röhl, Matthias John, Ed Yaworski, Jens Harborth, Amy C.H. Lee, Muthiah Manoharan, Stephan Seiffert, James Heyes, David Bumcrot, Amanda J. Wheat, Victor Koteliansky, Lubomir Nechev
المصدر: Nature. 441:111-114
مصطلحات موضوعية: Primates, Small interfering RNA, Multidisciplinary, MRNA cleavage, Stable nucleic acid lipid particle, RNA, Pharmacology, Biology, Molecular biology, RNAi Therapeutics, RNA silencing, Phenotype, RNA interference, Animals, Gene silencing, RNA Interference, RNA, Messenger, RNA, Small Interfering, Apolipoproteins B
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf5bcd46f67e5d2c5a34ff185d98a71Test
https://doi.org/10.1038/nature04688Test -
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المؤلفون: Matthias John, Gerhard Heil, Olaf Heidenreich, Philipp Hadwiger, Juergen Krauter, Alfred Nordheim, Heidemarie Riehle, Hans-Peter Vornlocher
المصدر: Blood. 101:3157-3163
مصطلحات موضوعية: Small interfering RNA, Oncogene Proteins, Fusion, Chromosomes, Human, Pair 21, Cellular differentiation, Immunology, Transitive RNA interference, Receptor, Macrophage Colony-Stimulating Factor, Transfection, Biochemistry, Translocation, Genetic, Transforming Growth Factor beta1, RUNX1 Translocation Partner 1 Protein, Transforming Growth Factor beta, hemic and lymphatic diseases, Enhancer binding, CCAAT-Enhancer-Binding Protein-alpha, Tumor Cells, Cultured, Humans, RNA, Messenger, RNA, Small Interfering, neoplasms, Tumor Stem Cell Assay, Cell Size, Cholecalciferol, CD11b Antigen, Ccaat-enhancer-binding proteins, Oncogene, biology, Gene Expression Regulation, Leukemic, Myeloid leukemia, Cell Differentiation, Cell Biology, Hematology, Transforming growth factor beta, Molecular biology, Neoplasm Proteins, Leukemia, Myeloid, Drug Design, Acute Disease, Core Binding Factor Alpha 2 Subunit, Cancer research, biology.protein, RNA Interference, Chromosomes, Human, Pair 8, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e92c8ed88006893637fccb8f69ce5e8aTest
https://doi.org/10.1182/blood-2002-05-1589Test -
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المؤلفون: Dominik A. Megger, Ruth Broering, Kerstin Jahn-Hofmann, Matthias John, CI Real, Helmut E. Meyer, Guido Gerken, Joerg F. Schlaak, Martin Eisenacher, Katja Kuhlmann, Joerg Timm, Andreas Walker, L Ickenstein, Barbara Sitek
مصطلحات موضوعية: Hydroxymethylglutaryl-CoA Synthase, Heterogeneous nuclear ribonucleoprotein, Proteome, Macromolecular Substances, Medizin, Hepacivirus, Biology, Virus Replication, Heterogeneous-Nuclear Ribonucleoprotein K, Mice, Liver Neoplasms, Experimental, Thioredoxins, RNA interference, Interferon, Virology, Heterogeneous nuclear ribonucleoprotein A3, Cell Line, Tumor, Heterogeneous-Nuclear Ribonucleoprotein Group A-B, medicine, Animals, RNA, Small Interfering, Ubiquitins, Pharmacology, Interferon-stimulated gene, Transfection, ISG15, Isocitrate Dehydrogenase, Mice, Inbred C57BL, Ribonucleoproteins, biology.protein, Hepatocytes, Cytokines, Nanoparticles, RNA Interference, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca8456de8c8f718784fde25cafd96eb0Test
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=84887146863Test -
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المؤلفون: Silke Metz, Eike Hoffmann, Weijun Cheng, Kerstin Jahn-Hofmann, Jan Olaf Stracke, Werner Scheuer, Britta Schneider, Olaf Mundigl, Hans Herweijer, Wilma Lau, Simone Dill, Matthias John, Ludger M lckenstein, Karin Daub, Zane C. Neal, Michael Grote, James Ludtke, Rebecca Croasdale, Frieder Bauss, Alexander Haas, Helmut Burtscher, Birgit Bramlage, Ulrjch Brinkmann
المصدر: Molecular Therapy: Nucleic Acids, Vol 1, Iss C (2012)
Molecular Therapy. Nucleic Acidsمصطلحات موضوعية: siRNA delivery, Small interfering RNA, Gene knockdown, Messenger RNA, medicine.diagnostic_test, lcsh:RM1-950, CD22, Biology, lipid nanoparticle, Molecular biology, Flow cytometry, bispecific antibody, chemistry.chemical_compound, dynamic polyconjugate, RNA interference, lcsh:Therapeutics. Pharmacology, chemistry, Antigen, hapten, Drug Discovery, medicine, Molecular Medicine, Digoxigenin, Original Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb0d21ca8c5f857cf9217edf1aa26a8Test
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المؤلفون: Anke Geick, Kerstin Jahn-Hofmann, Monika Krampert, Jennifer Rice, Andrea Schuster, Khursheed Anwer, Richard Congo, Hans-Peter Vornlocher, Gregory Slobodkin, Jason G. Fewell, Diane McClure, Matthias John, Jeff Sparks, Angela Rea-Ramsey, Kevin Polach, Majed Matar, Elaine Brunhoeber
المصدر: Molecular therapy : the journal of the American Society of Gene Therapy. 20(1)
مصطلحات موضوعية: Small interfering RNA, Transgene, Mice, Transgenic, Nanoconjugates, Respiratory Mucosa, Biology, Transfection, Polyethylene Glycols, Mice, RNA interference, In vivo, Drug Discovery, Genetics, Gene silencing, Animals, Gene Silencing, RNA, Small Interfering, Molecular Biology, Lung, Pharmacology, Gene knockdown, Mice, Inbred ICR, Biogenic Polyamines, RNA, Molecular biology, Blood Cell Count, Injections, Intravenous, Cancer research, Molecular Medicine, Female, Original Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4d447681d45dce4a2223b795d8d66aTest
https://pubmed.ncbi.nlm.nih.gov/21988874Test -
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المؤلفون: June Qin, Klaus Charisse, Kallanthottathil G. Rajeev, Akin Akinc, Rajendra K. Pandey, Martin Egli, Kathy Mills, Philipp Hadwiger, Lubomir Nechev, Pradeep S. Pallan, Muthiah Manoharan, Emily M. Greene, Martin Maier, Matthias John, Eriks Rozners
المصدر: Angewandte Chemie (International ed. in English). 50(10)
مصطلحات موضوعية: Small interfering RNA, Binding Sites, Chemistry, Drug discovery, RNA-induced silencing complex, RNA, General Medicine, General Chemistry, Fluorine, Crystallography, X-Ray, Catalysis, Article, Cell biology, Protein Structure, Tertiary, Protein structure, Biochemistry, RNA interference, Gene silencing, Nucleic Acid Conformation, RNA-Induced Silencing Complex, Thermodynamics, Gene Silencing, Binding site, RNA, Small Interfering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a39dd22d14d3974a17bab99a42aa31Test
https://pubmed.ncbi.nlm.nih.gov/21351337Test -
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المؤلفون: Sabrina Höbel, Matthias John, Frank Czubayko, Hans-Peter Vornlocher, Ivette Koburger, Philipp Hadwiger, Achim Aigner
المصدر: The Journal of Gene Medicine.
مصطلحات موضوعية: Vascular Endothelial Growth Factor A, Small interfering RNA, Angiogenesis, Mice, Nude, Angiogenesis Inhibitors, Biology, Antibodies, Monoclonal, Humanized, Mice, chemistry.chemical_compound, In vivo, RNA interference, Neoplasms, Drug Discovery, Genetics, Animals, Polyethyleneimine, RNA, Small Interfering, Molecular Biology, Genetics (clinical), Gene knockdown, Polyethylenimine, Antibodies, Monoclonal, Genetic Therapy, Combined Modality Therapy, Xenograft Model Antitumor Assays, Molecular biology, Bevacizumab, Vascular endothelial growth factor, chemistry, Gene Knockdown Techniques, Cancer research, Systemic administration, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce044be47bf7a8164420c812477c7fbTest
https://doi.org/10.1002/jgm.1431Test