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المؤلفون: Matthias John, Tirtha Chakraborty, Nahum Sonenberg, Yuri V. Svitkin, Yi Min Cheng, Vladimir Presnyak
المصدر: Nucleic Acids Research
مصطلحات موضوعية: 0301 basic medicine, RNA Stability, Eukaryotic Initiation Factor-2, Biology, Transfection, Cell Line, 03 medical and health sciences, Mice, eIF-2 Kinase, 0302 clinical medicine, Polysome, Prokaryotic translation, Genetics, Initiation factor, Animals, Humans, Ribosome profiling, RNA, Messenger, Phosphorylation, Cell-Free System, EIF4E, Translation (biology), Fibroblasts, Cell biology, Enzyme Activation, Internal ribosome entry site, 030104 developmental biology, HEK293 Cells, Biochemistry, Polyribosomes, Protein Biosynthesis, RNA, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, EF-Tu, Pseudouridine, HeLa Cells
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512e629d27771b5f71b50beb6769c2ebTest
https://pubmed.ncbi.nlm.nih.gov/28334758Test -
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المؤلفون: Alistair Miller, Weisan Chen, Matthias John, Ashley M. Jacobi, Jessica M Moffat, Bryan R.G. Williams, Soroush T. Sarvestani, Justine D. Mintern, Michael P. Gantier, Simone A. Beckham, Meredith O'Keeffe, Mark A. Behlke, Michelle D. Tate, Claire E. McCoy
المصدر: Journal of Virology. 88:799-810
مصطلحات موضوعية: Male, Small interfering RNA, Adenosine, Adenosine Deaminase, Molecular Sequence Data, Immunology, Alpha interferon, Microbiology, Mice, Influenza A Virus, H1N1 Subtype, Adenosine deaminase, Virology, Influenza, Human, medicine, Animals, Humans, Inosine, Mice, Knockout, Base Sequence, biology, Interferon-alpha, virus diseases, RNA, TLR7, Virus-Cell Interactions, Cell biology, Toll-Like Receptor 7, Toll-Like Receptor 8, RNA editing, Insect Science, ADAR, Leukocytes, Mononuclear, biology.protein, Nucleic Acid Conformation, RNA, Viral, Female, RNA Editing, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d882229699b162d32e8cb44cb912de84Test
https://doi.org/10.1128/jvi.01571-13Test -
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المؤلفون: Darren H. Wakefield, Kerstin Jahn-Hofmann, Julia Hegge, Claudia E. Oropeza, Hans-Peter Vornlocher, Markus Hossbach, Qili Chu, David B. Rozema, Ingo Roehl, Alan McLachlan, Holly Hamilton, Philipp Hadwiger, Christine I. Wooddell, Matthias John, Jason Klein, Jochen Deckert, David L. Lewis
المصدر: Molecular Therapy
مصطلحات موضوعية: Male, Hepatitis B virus, Small interfering RNA, Acetylgalactosamine, Genotype, Biology, medicine.disease_cause, Virus, RNAi Therapeutics, Mice, Drug Delivery Systems, Hepatitis B, Chronic, RNA interference, Drug Discovery, medicine, Genetics, Animals, Humans, Amino Acid Sequence, RNA, Small Interfering, Molecular Biology, Pharmacology, Gene knockdown, Binding Sites, RNA, Genetic Therapy, Virology, Macaca fascicularis, Cholesterol, Gene Knockdown Techniques, Hepatocytes, RNA, Viral, Molecular Medicine, Original Article, Female, RNA Interference, Peptides, Viral load
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd54760eecf60d79cd46602fcf7f0c3aTest
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المؤلفون: Anna Roth, Anthony J. Sadler, Kerstin Jahn-Hofmann, Matthew C.J. Wilce, Die Wang, Jason M. Brouwer, Matthias John, Simone A. Beckham, Jacqueline A. Wilce, Bryan R.G. Williams
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Models, Molecular, viruses, Retinoic acid, chemical and pharmacologic phenomena, Plasma protein binding, Biology, Protein Structure, Secondary, DEAD-box RNA Helicases, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, X-Ray Diffraction, Structural Biology, Scattering, Small Angle, Genetics, Humans, Trypsin, Receptors, Immunologic, DEAD Box Protein 58, Protein Structure, Quaternary, 030304 developmental biology, RNA, Double-Stranded, 0303 health sciences, RIG-I, RNA, virus diseases, MDA5, biochemical phenomena, metabolism, and nutrition, Peptide Fragments, Cell biology, Protein Structure, Tertiary, RNA silencing, chemistry, Biochemistry, Cytoplasm, Proteolysis, Chromatography, Gel, biological phenomena, cell phenomena, and immunity, Apoproteins, 030217 neurology & neurosurgery, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a0cdee54b0c228a51711465017a317Test
http://europepmc.org/articles/PMC3597671Test -
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المؤلفون: Ivanka Toudjarska, Jürgen Soutschek, Vandana Sood, Kevin McClintock, Akin Akinc, Birgit Bramlage, Matthew N. Fedoruk, Timothy Racie, Adam Judge, Ian MacLachlan, Hans-Peter Vornlocher, Lorne R. Palmer, Lloyd Jeffs, Kieu Lam, Sumi Shanmugam, William Zedalis, Tracy Zimmermann, Ingo Röhl, Matthias John, Ed Yaworski, Jens Harborth, Amy C.H. Lee, Muthiah Manoharan, Stephan Seiffert, James Heyes, David Bumcrot, Amanda J. Wheat, Victor Koteliansky, Lubomir Nechev
المصدر: Nature. 441:111-114
مصطلحات موضوعية: Primates, Small interfering RNA, Multidisciplinary, MRNA cleavage, Stable nucleic acid lipid particle, RNA, Pharmacology, Biology, Molecular biology, RNAi Therapeutics, RNA silencing, Phenotype, RNA interference, Animals, Gene silencing, RNA Interference, RNA, Messenger, RNA, Small Interfering, Apolipoproteins B
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bf5bcd46f67e5d2c5a34ff185d98a71Test
https://doi.org/10.1038/nature04688Test -
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المؤلفون: Michael Fleischhacker, E. Engel, Matthias John, Sabine Weickmann, T. Carstensen, Christian Witt, Bernd Schmidt
المصدر: Lung Cancer. 48:145-147
مصطلحات موضوعية: Adult, Male, Pulmonary and Respiratory Medicine, Cancer Research, Pathology, medicine.medical_specialty, Lung Neoplasms, Sensitivity and Specificity, chemistry.chemical_compound, Carcinoma, Non-Small-Cell Lung, Biomarkers, Tumor, medicine, Humans, Carcinoma, Small Cell, Lung cancer, Aged, Aged, 80 and over, medicine.diagnostic_test, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Cancer, RNA, DNA, Neoplasm, Middle Aged, medicine.disease, Molecular biology, Cell-Free Nucleic Acids, Bronchoalveolar lavage, Oncology, chemistry, Nucleic acid, Female, RNA extraction, business, Bronchoalveolar Lavage Fluid, DNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca11bdf76458158f75a88959f0540a1eTest
https://doi.org/10.1016/j.lungcan.2004.09.013Test -
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المؤلفون: Anke Geick, Kerstin Jahn-Hofmann, Monika Krampert, Jennifer Rice, Andrea Schuster, Khursheed Anwer, Richard Congo, Hans-Peter Vornlocher, Gregory Slobodkin, Jason G. Fewell, Diane McClure, Matthias John, Jeff Sparks, Angela Rea-Ramsey, Kevin Polach, Majed Matar, Elaine Brunhoeber
المصدر: Molecular therapy : the journal of the American Society of Gene Therapy. 20(1)
مصطلحات موضوعية: Small interfering RNA, Transgene, Mice, Transgenic, Nanoconjugates, Respiratory Mucosa, Biology, Transfection, Polyethylene Glycols, Mice, RNA interference, In vivo, Drug Discovery, Genetics, Gene silencing, Animals, Gene Silencing, RNA, Small Interfering, Molecular Biology, Lung, Pharmacology, Gene knockdown, Mice, Inbred ICR, Biogenic Polyamines, RNA, Molecular biology, Blood Cell Count, Injections, Intravenous, Cancer research, Molecular Medicine, Female, Original Article
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b4d447681d45dce4a2223b795d8d66aTest
https://pubmed.ncbi.nlm.nih.gov/21988874Test -
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المؤلفون: Sébastien Pfeffer, Matthias John
المصدر: Antiviral RNAi ISBN: 9781617790362
مصطلحات موضوعية: Gel electrophoresis, Nucleic acid thermodynamics, chemistry.chemical_compound, Chemistry, Oligonucleotide, Hybridization probe, RNA, Nuclease protection assay, Non-coding RNA, Molecular biology, DNA
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c921062e7665c6d039969641df919180Test
https://doi.org/10.1007/978-1-61779-037-9_10Test -
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المؤلفون: June Qin, Klaus Charisse, Kallanthottathil G. Rajeev, Akin Akinc, Rajendra K. Pandey, Martin Egli, Kathy Mills, Philipp Hadwiger, Lubomir Nechev, Pradeep S. Pallan, Muthiah Manoharan, Emily M. Greene, Martin Maier, Matthias John, Eriks Rozners
المصدر: Angewandte Chemie (International ed. in English). 50(10)
مصطلحات موضوعية: Small interfering RNA, Binding Sites, Chemistry, Drug discovery, RNA-induced silencing complex, RNA, General Medicine, General Chemistry, Fluorine, Crystallography, X-Ray, Catalysis, Article, Cell biology, Protein Structure, Tertiary, Protein structure, Biochemistry, RNA interference, Gene silencing, Nucleic Acid Conformation, RNA-Induced Silencing Complex, Thermodynamics, Gene Silencing, Binding site, RNA, Small Interfering
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a39dd22d14d3974a17bab99a42aa31Test
https://pubmed.ncbi.nlm.nih.gov/21351337Test -
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المؤلفون: Jason Fuller, Valentina Busini, Naushad Hossain, Muthiah Manoharan, Andreas Zumbuehl, Timothy Racie, Rene Alvarez, Ivanka Toudjarska, Todd Borland, Kallanthottathil G. Rajeev, Jürgen Soutschek, Matthias John, Rainer Constien, Tracy Zimmermann, Dinah W.Y. Sah, Victor Koteliansky, K. Narayanannair Jayaprakash, Antonin de Fougerolles, Anna Borodovsky, Robert Langer, Akin Akinc, Elizaveta S. Leshchiner, June Qin, Denitza Raitcheva, Daniel G. Anderson, Michael S. Goldberg, Sergio Bacallado, David N. Nguyen, J. Robert Dorkin, Hans-Peter Vornlocher, Lubomir Nechev, Muthusamy Jayaraman
المصدر: Nature Biotechnology, Vol. 26, No 5 (2008) pp. 561-569
Nature Biotechnologyمصطلحات موضوعية: Drug Carriers, Small interfering RNA, Biomedical Engineering, RNA, Bioengineering, Computational biology, Biology, Bioinformatics, Lipids, Applied Microbiology and Biotechnology, Article, RNAi Therapeutics, Animal model, RNA interference, Drug Design, microRNA, ddc:540, Combinatorial Chemistry Techniques, Molecular Medicine, Gene silencing, RNA Interference, Delivery system, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb1e02aa83371950ef1de530b3e00bcTest
http://hdl.handle.net/11311/513099Test