المؤلفون: Tsai, Chia-Lin, Chou, Chung-Hsing, Lee, Pei-Jung, Yin, Jiu-Haw, Chen, Shao-Yuan, Lin, Chun-Chieh, Sung, Yueh-Feng, Yang, Fu-Chi, Chung, Chi-Hsiang, Chien, Wu-Chien, Tsai, Chia-Kuang, Lee, Jiunn-Tay

مصطلحات موضوعية: Tension-type headache, Migraine, Non-migrainous headache, Ischaemic stroke, Risk factor

الوصف: Background Headache such as migraine is associated with stroke. Studies focused on primary headache disorders (PHDs) as a risk factor for stroke are limited. The purpose of this population-based cohort study was to explore whether patients with PHDs were at a high risk for developing stroke. Methods A total of 1346 patients with PHDs were enrolled and compared with 5384 age-, gender- and co-morbidity-matched control cohorts. International Classification of Diseases, Clinical Modification codes were administered for the definition of PHDs, stroke, and stroke risk factors. Cox proportional-hazards regressions were performed for investigating hazard ratios (HR). Results PHDs patients exhibited a 1.49 times (95% CI :1.15–1.98, p < 0.01) higher risk for developing ischaemic stroke compared with that of control cohorts. Both migraine (HR = 1.22, 95% CI :1.13–1.97, p < 0.05) and tension-type headache (HR = 2.29, 95% CI :1.22–2.80, p < 0.01) were associated with an increased risk of ischemic stroke. Females with PHDs were at greater risk of developing ischaemic stroke (HR = 1.49, 95% CI :1.13–1.90, p < 0.01) than those without PHDs. PHDs patient aged 45 to 64 years displayed significantly higher risk to develop ischaemic stroke (HR = 1.50, 95% CI: 1.11–2.10, p < 0.05) than the matched controls. The impact of PHDs on ischaemic stroke risk became gradually apparent by different following time intervals beyond 2 years after first diagnosis. Conclusion PHDs is suggestive of an incremental risk for ischaemic stroke with gender-dependent, age-specific and time-dependent characteristics.

العلاقة: http://www.thejournalofheadacheandpain.com/content/17/1/108Test

الإتاحة: http://www.thejournalofheadacheandpain.com/content/17/1/108Test

المؤلفون: Yin, Jiu-Haw, Tsai, Chia-Lin, Lee, Pei-Jung, Chou, Chung-Hsing, Chen, Shao-Yuan, Chung, Chi-Hsiang, Chien, Wu-Chien, Lin, Chun-Chieh, Sung, Yueh-Feng, Yang, Fu-Chi, Tsai, Chia-Kuang, Lee, Jiunn-Tay

المصدر: Medicine

مصطلحات موضوعية: Adult, Male, Headache Disorders, Primary, Databases, Factual, Taiwan, Observational Study, Sex Factors, vascular, International Classification of Diseases, Risk Factors, mental disorders, Humans, migraine, Longitudinal Studies, Aged, Proportional Hazards Models, Retrospective Studies, Age Factors, Middle Aged, risk factor, Alzheimer, Regression Analysis, Dementia, Female, headache, Research Article

الوصف: Dementia is a global burden of public health. Headache disorders are the third most common cause of disability worldwide and common problems in the elderly population. Few studies focused on the relationship between primary headache disorders (PHDs) and cognitive status, and the results remain controversial. The aim of this countrywide, population-based, retrospective study was to investigate potential association between PHDs and dementia risk. We enrolled 1346 cases with PHDs to match the 5384 individuals by age, gender and co-morbidities. The definition of PHDs, dementia, and risk factors of dementia was identified according to The International Classification of Diseases, Ninth Revision, Clinical Modification. Cox regression was administered for estimating hazard ratios (HR) for dementia. During more than 5 years of follow-up, PHDs individuals had 1.52 times (P

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::23590a8d6a87e230c06a4be364c1561cTest
http://europepmc.org/articles/PMC6314725Test