يعرض 1 - 10 نتائج من 156 نتيجة بحث عن '"IFIH1"', وقت الاستعلام: 0.87s تنقيح النتائج
  1. 1
    دورية أكاديمية
    RIG-I-Like Receptor Signaling in Singleton-Merten Syndrome

    المؤلفون: Changming Lu, Mary MacDougall

    المصدر: Frontiers in Genetics, Vol 8 (2017)

    مصطلحات موضوعية: Singleton-Merten syndrome, IFIH1, DDX58, MDA5, RIG-I, Genetics, QH426-470

    وصف الملف: electronic resource

    العلاقة: http://journal.frontiersin.org/article/10.3389/fgene.2017.00118/fullTest; https://doaj.org/toc/1664-8021Test

    الوصول الحر: https://doaj.org/article/1d88f80a76b04a20a1a8ffe735b7e993Test

    View record in DOAJ النص الكامل

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  2. 2
    SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling pathways

    المؤلفون: Lulu Han, Pei-Hui Wang, Jian Deng, Jing Zhang, Meng Wei Zhuang, Mei Ling Nan, Xue Jing Zhang, Yi Zheng, Chengjiang Gao

    المصدر: Journal of Medical Virology

    مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, viruses, Virus Replication, SARS‐CoV‐2, 0302 clinical medicine, Interferon, Chlorocebus aethiops, 030212 general & internal medicine, Receptors, Immunologic, skin and connective tissue diseases, Research Articles, RIG-I, virus diseases, Signal transducing adaptor protein, Nucleotidyltransferases, I-kappa B Kinase, antiviral immunity, Infectious Diseases, Vesicular stomatitis virus, DEAD Box Protein 58, 030211 gastroenterology & hepatology, Signal transduction, Plasmids, Signal Transduction, Research Article, IFNs, medicine.drug, Protein Serine-Threonine Kinases, Biology, Transfection, ORF9b, 03 medical and health sciences, COVID‐19, Virology, medicine, Animals, Coronavirus Nucleocapsid Proteins, Humans, Vero Cells, Adaptor Proteins, Signal Transducing, Immune Evasion, SARS-CoV-2, fungi, Membrane Proteins, biochemical phenomena, metabolism, and nutrition, Phosphoproteins, biology.organism_classification, Immunity, Innate, Toll-Like Receptor 3, Adaptor Proteins, Vesicular Transport, HEK293 Cells, Gene Expression Regulation, TRIF, TLR3, Interferon Regulatory Factor-3, Interferons, IRF3, HeLa Cells

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378faf81bbd134d651ba57cea4c75d0cTest
    https://doi.org/10.1002/jmv.27050Test


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  3. 3
    Differential roles of RIG-I like receptors in SARS-CoV-2 infection

    المؤلفون: Duomeng Yang, Tingting Geng, Andrew G. Harrison, Penghua Wang

    المصدر: Military Medical Research, Vol 8, Iss 1, Pp 1-3 (2021)
    bioRxiv
    article-version (status) pre
    article-version (number) 1

    مصطلحات موضوعية: Medicine (General), Interferon-Induced Helicase, IFIH1, MDA5, PRR, viruses, coronavirus, severe acute respiratory syndrome, Retinoic acid-inducible gene I, Virus Replication, Article, Cell Line, Interferon Lambda, RIG-I, Immune system, R5-920, Interferon, medicine, Humans, Receptors, Immunologic, Mitochondrial antiviral-signaling protein, Adaptor Proteins, Signal Transducing, Melanoma differentiation-associated protein 5, business.industry, SARS-CoV-2, Pathogen pattern recognition receptor, COVID-19, virus diseases, General Medicine, biochemical phenomena, metabolism, and nutrition, Virology, Military Science, Viral replication, Cell culture, Interferon Type I, DEAD Box Protein 58, Angiotensin-Converting Enzyme 2, Interferons, Signal transduction, business, medicine.drug, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2a1fc9b721fb866750c5e8d019b4fbTest
    https://doaj.org/article/2cc1ffe7ba624aa098f791eea71ade17Test


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  4. 4
    RIG-I and MDA5 Protect Mice From Pichinde Virus Infection by Controlling Viral Replication and Regulating Immune Responses to the Infection

    المؤلفون: Morgan Brisse, Qinfeng Huang, Mizanur Rahman, Da Di, Yuying Liang, Hinh Ly

    المصدر: Frontiers in Immunology
    Frontiers in Immunology, Vol 12 (2021)

    مصطلحات موضوعية: Mice, Knockout, mammarenavirus, MDA5, Interferon-Induced Helicase, IFIH1, viruses, Immunology, Receptors, Cell Surface, RC581-607, Virus Replication, RIG-I, Mice, Immunology and Allergy, Animals, Arenaviridae Infections, Immunologic diseases. Allergy, arenavirus, Pichinde virus, innate immunity, Original Research, nucleoprotein

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5179ab5d5bb03d9f12ddc5d02d4f0c54Test
    http://europepmc.org/articles/PMC8677829Test


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  5. 5
    Spatiotemporal dynamics of innate immune signaling via RIG-I–like receptors

    المؤلفون: Lauren D. Hatfield, Katharina Esser-Nobis, Michael Gale

    المصدر: Proc Natl Acad Sci U S A

    مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, viruses, Humans, RNA, Double-Stranded, Multidisciplinary, Innate immune system, RIG-I, Chemistry, LGP2, virus diseases, RNA, Signal transducing adaptor protein, MDA5, Biological Sciences, biochemical phenomena, metabolism, and nutrition, Immunity, Innate, Mitochondria, Cell biology, RNA silencing, Virus Diseases, DEAD Box Protein 58, RNA, Viral, Interferon Regulatory Factor-3, IRF3, RNA Helicases, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c78a8570f292ca5ace77fb4123113eb8Test
    https://doi.org/10.1073/pnas.1921861117Test


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  6. 6
    Oligomerization of RIG‐I and MDA5 2CARD domains

    المؤلفون: James L. Cole, David J. Mouser, Cassie M. Zerbe

    المصدر: Protein Sci

    مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, Biochemistry, 03 medical and health sciences, Protein Domains, Tetramer, Humans, Receptors, Immunologic, Receptor, Molecular Biology, 030304 developmental biology, 0303 health sciences, Innate immune system, biology, RIG-I, Chemistry, 030302 biochemistry & molecular biology, Helicase, MDA5, Articles, CARD domain, biology.protein, Biophysics, DEAD Box Protein 58, Protein Multimerization, Function (biology), Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa37746a9b2800723c18c5a35a54731dTest
    https://doi.org/10.1002/pro.3776Test


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  7. 7
    RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection

    المؤلفون: Emily A. Hemann, Amy E. L. Stone, Michael Gale, Courtney Wilkins, Richard Green

    المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
    Nature Communications

    مصطلحات موضوعية: 0301 basic medicine, Male, Interferon-Induced Helicase, IFIH1, Science, animal diseases, viruses, Macrophage polarization, General Physics and Astronomy, chemical and pharmacologic phenomena, 02 engineering and technology, Biology, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, Animals, Humans, Receptor, lcsh:Science, Mice, Knockout, Multidisciplinary, Innate immune system, RIG-I, Macrophages, LGP2, ATF4, Cell Polarity, virus diseases, MDA5, General Chemistry, biochemical phenomena, metabolism, and nutrition, 021001 nanoscience & nanotechnology, Phenotype, Virology, 3. Good health, Mice, Inbred C57BL, 030104 developmental biology, Viral infection, RIG-I-like receptors, DEAD Box Protein 58, Female, lcsh:Q, 0210 nano-technology, West Nile virus, West Nile Fever

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d14b6863f26eaff64623361a6e4770Test
    http://link.springer.com/article/10.1038/s41467-019-11250-5Test


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  8. 8
    Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage

    المؤلفون: Sioofy-Khojine, Amir-Babak, Richardson, Sarah J, Locke, Jonathan M, Oikarinen, Sami, Nurminen, Noora, Laine, Antti-Pekka, Downes, Kate, Lempainen, Johanna, Todd, John A, Veijola, Riitta, Ilonen, Jorma, Knip, Mikael, Morgan, Noel G, Hyöty, Heikki, Peakman, Mark, Eichmann, Martin

    المساهمون: Sioofy-Khojine, Amir-Babak [0000-0001-5538-5153], Richardson, Sarah J [0000-0002-1160-6062], Locke, Jonathan M [0000-0001-9516-5251], Oikarinen, Sami [0000-0003-3901-6774], Nurminen, Noora [0000-0002-6798-7677], Laine, Antti-Pekka [0000-0003-4962-2882], Lempainen, Johanna [0000-0001-9893-1468], Todd, John A [0000-0003-2740-8148], Veijola, Riitta [0000-0002-6557-270X], Ilonen, Jorma [0000-0002-9973-2062], Knip, Mikael [0000-0003-0474-0033], Morgan, Noel G [0000-0003-1537-8113], Hyöty, Heikki [0000-0003-0370-4145], Peakman, Mark [0000-0003-3328-3513], Eichmann, Martin [0000-0002-8675-2822], Apollo - University of Cambridge Repository, Tampere University, BioMediTech, Department of Clinical Microbiology, Department of Paediatrics, HUS Children and Adolescents, Children's Hospital, University of Helsinki, CAMM - Research Program for Clinical and Molecular Metabolism

    المصدر: Diabetologia. 65(10)

    مصطلحات موضوعية: EXPRESSION, Adult, MDA5, Interferon-Induced Helicase, IFIH1, Endocrinology, Diabetes and Metabolism, Pancreatic islets, Insulins, CHILDREN, Autoimmunity, FUNCTION MUTATIONS, DIAGNOSIS, 3121 Internal medicine, IFIH-1, RIG-I, DEAD-box RNA Helicases, MELLITUS, INFECTION, Internal Medicine, Interferon induced with helicase C domain 1, Enterovirus Infections, Humans, Genetic Predisposition to Disease, Child, Alleles, Autoantibodies, Enterovirus, Genetic risk, CAPSID PROTEIN VP1, Melanoma differentiation-associated protein 5, RECOGNITION, rs1990760, HLA GENOTYPES, Type 1 diabetes, Diabetes Mellitus, Type 1, 3121 General medicine, internal medicine and other clinical medicine, Leukocytes, Mononuclear, RNA, 3111 Biomedicine

    وصف الملف: application/pdf; text/xml; fulltext

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3a0514c44ea99ffc8cceef715deb10Test
    https://pubmed.ncbi.nlm.nih.gov/35867130Test


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  9. 9
    The molecular mechanism of RIG-I activation and signaling

    المؤلفون: Rong Guo, Wenshuai Wang, Anna Marie Pyle, Daniel Thoresen, Drew Galls, Ling Xu

    المصدر: Immunological reviews. 304(1)

    مصطلحات موضوعية: Interferon-Induced Helicase, IFIH1, RIG-I, viruses, Immunology, LGP2, Pattern recognition receptor, RNA, MDA5, Biology, Immunity, Innate, Cell biology, DEAD-box RNA Helicases, RNA silencing, Transcription (biology), Interferon, medicine, Immunology and Allergy, RNA, Viral, medicine.drug, RNA, Double-Stranded, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a8d7feb78a954734d77f26e37899495Test
    https://pubmed.ncbi.nlm.nih.gov/34514601Test


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  10. 10
    OAS1/RNase L executes RIG-I ligand-dependent tumor cell apoptosis

    المؤلفون: Carina C. de Oliveira Mann, Stefan Endres, Stefan F. Lichtenthaler, Max Schnurr, Meino Rohlfs, Simon Rothenfusser, Daniel F. R. Boehmer, Philipp Metzger, Christine Hörth, Karl-Peter Hopfner, Lorenz Kocheise, Caroline C. Friedel, Michael Kluge, Simone Formisano, Lars M. Koenig, Peter Duewell, Stephan Mueller

    المصدر: Science immunology 6(61), eabe2550 (2021). doi:10.1126/sciimmunol.abe2550

    مصطلحات موضوعية: 0301 basic medicine, Interferon-Induced Helicase, IFIH1, RNase P, Receptors, Retinoic Acid, Immunology, Priming (immunology), genetics [Interferon-Induced Helicase, IFIH1], Apoptosis, genetics [2',5'-Oligoadenylate Synthetase], Ligands, immunology [Neoplasms], Proinflammatory cytokine, 03 medical and health sciences, Mice, 0302 clinical medicine, genetics [Adaptor Proteins, Signal Transducing], Cell Line, Tumor, Neoplasms, Endoribonucleases, immunology [Receptors, Retinoic Acid], 2',5'-Oligoadenylate Synthetase, immunology [2',5'-Oligoadenylate Synthetase], genetics [Receptors, Immunologic], Animals, Humans, ddc:610, Receptors, Immunologic, Adaptor Proteins, Signal Transducing, RIG-I, Effector, Chemistry, Intrinsic apoptosis, General Medicine, Coculture Techniques, Cell biology, 030104 developmental biology, genetics [DEAD Box Protein 58], immunology [Endoribonucleases], 030220 oncology & carcinogenesis, DEAD Box Protein 58, Cytokine secretion, genetics [Endoribonucleases]

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d231f0bb710a301bb77b9b5e8c43105Test
    https://pubmed.ncbi.nlm.nih.gov/34272227Test


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