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1
المؤلفون: Handan He, Heidi J. Einolf, Christina S. Won, Lai Wang, Helen Gu, Wen Lin, Dung Yu Chun, James B. Mangold
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 45(12)
مصطلحات موضوعية: Physiologically based pharmacokinetic modelling, Indoles, medicine.drug_class, Midazolam, Pharmaceutical Science, Pharmacology, Hydroxamic Acids, 030226 pharmacology & pharmacy, Models, Biological, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, In vivo, Panobinostat, medicine, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Humans, Drug Interactions, Chemistry, Histone deacetylase inhibitor, Area under the curve, Gastric Acidity Determination, Drug interaction, Cytochrome P-450 CYP2C19, Histone Deacetylase Inhibitors, 030220 oncology & carcinogenesis, Enzyme Induction, Microsomes, Liver, Ketoconazole, Rifampin, Oxidation-Reduction, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38cd9dac1e23d8ca3898d85896f59acaTest
https://pubmed.ncbi.nlm.nih.gov/28912253Test -
2
المؤلفون: Christina S. Won, Lai Wang, Jocelyn Zhou, Sam Rebello, Heidi J. Einolf
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 45(4)
مصطلحات موضوعية: Drug, Adult, Male, Physiologically based pharmacokinetic modelling, Time Factors, CYP3A, Metabolic Clearance Rate, Pyridines, media_common.quotation_subject, Cmax, Pharmaceutical Science, Pharmacology, 030226 pharmacology & pharmacy, Models, Biological, Sonidegib, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Pharmacokinetics, Neoplasms, Medicine, Cytochrome P-450 CYP3A, Humans, Computer Simulation, Drug Interactions, Dosing, media_common, business.industry, Biphenyl Compounds, Cytochrome P-450 CYP3A Inducers, Middle Aged, Smoothened Receptor, Healthy Volunteers, Ketoconazole, chemistry, 030220 oncology & carcinogenesis, Cytochrome P-450 CYP3A Inhibitors, Female, Rifampin, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19413d02d53b18c1ea6a8a9c3fe17ae9Test
https://pubmed.ncbi.nlm.nih.gov/28122787Test -
3
المؤلفون: Xuemin, Jiang, Catherine, Dutreix, Venkateswar, Jarugula, Sam, Rebello, Christina S, Won, Haiying, Sun
المصدر: Clinical pharmacology in drug development. 6(1)
مصطلحات موضوعية: Adult, Male, Young Adult, Cytochrome P-450 CYP3A Inducers, Humans, Drug Interactions, Female, Middle Aged, Models, Theoretical, Rifampin, Healthy Volunteers, Hydroxycholesterols
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::bba78f433852d3f98a1b368751963000Test
https://pubmed.ncbi.nlm.nih.gov/27138546Test