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المؤلفون: Jean-Marie Berthelot, Christelle Darrieutort-Laffite, Caroline Trang, Yves Maugars, Benoît Le Goff
المصدر: Revue du Rhumatisme. 89:359-364
مصطلحات موضوعية: Rheumatology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e15856339c877000ec3f5a23e36640b4Test
https://doi.org/10.1016/j.rhum.2022.03.007Test -
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المؤلفون: Jean-Marie Berthelot, Frédéric Douane, Stéphane Ploteau, Benoît Le Goff, Christelle Darrieutort-Laffite
المصدر: Revue du Rhumatisme. 89:365-371
مصطلحات موضوعية: Rheumatology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8e28ae8a9822913b01b69d564b28c849Test
https://doi.org/10.1016/j.rhum.2022.03.001Test -
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المؤلفون: Christelle Darrieutort-Laffite
المصدر: Revue du Rhumatisme Monographies. 89:51-56
مصطلحات موضوعية: Rheumatology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::591a6eef9e57684eaf69be273e1530e4Test
https://doi.org/10.1016/j.monrhu.2021.10.001Test -
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المؤلفون: Jean-Marc Ziza, Thomas W. Bauer, Louis Bernard, Beate Hyem, Géraldine Bart, Sophie Godot, E. Veillard, Pascal Guggenbuhl, Guillaume Coiffier, Denis Mulleman, Robert Touitou, Raphaèle Seror, Marion Baldeyrou, Pascal Coquerelle, Marion Couderc, Carine Salliot, Christian Lormeau, Bernard Fouquet, René-Marc Flipo, Christelle Darrieutort-Laffite
المصدر: Revue du Rhumatisme Monographies. 89:43-50
مصطلحات موضوعية: Rheumatology
الوصف: Resume L’arthrite septique (AS) sur articulation native de l’adulte est une affection rare mais qui constitue une urgence diagnostique en raison de la morbi-mortalite et du risque fonctionnel secondaire aux dommages structuraux. Sa prise en charge actuelle est heterogene et les recommandations disponibles sont anciennes. Le groupe de travail sur les infections osteo-articulaires de la Societe francaise de rhumatologie (SFR) en cooperation avec la Societe francaise de pathologies infectieuses de langue francaise (SPILF) et la Societe francaise de chirurgie orthopedique et traumatologique (SOFCOT) a travaille selon la methodologie HAS afin d’elaborer des recommandations de pratique clinique pour la prise en charge diagnostique et therapeutique des AS sur articulation native de l’adulte. Parmi les nouveautes, l’accent est mis sur l’importance de la documentation microbiologique (hemocultures et ponction articulaire) avant de debuter le traitement antibiotique, la recherche de diagnostics differentiels (recherche de microcristaux), la place de l’echographie articulaire pour guider une ponction, et l’indication a realiser une radiographie de reference. L’echographie cardiaque est indiquee seulement en cas d’AS a Staphylococcus aureus, streptocoques d’origine buccodentaire, Streptococcus gallolyticus, ou Enterococcus faecalis, ou de suspicion clinique d’endocardite infectieuse. Au plan therapeutique, nous insistons sur l’importance d’une collaboration medico-chirurgicale. L’antibiotherapie (molecules et durees) est presentee sous forme de tableaux didactiques en fonction des principaux germes en cause (staphylocoques, streptocoques et bacilles a Gram negatifs). L’antibiotherapie probabiliste est reservee aux patients presentant des signes de gravite. Enfin, les traitements non medicamenteux tels que le drainage de l’articulation et la reeducation precoce font l’objet de recommandations specifiques.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::eab4d10775fc871e6d5f9b7de50a8e93Test
https://doi.org/10.1016/j.monrhu.2021.08.003Test -
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المصدر: Joint bone spine. 90(3)
مصطلحات موضوعية: Rheumatology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52be74105a5900a3f2f6d63cdb2cc7e6Test
https://pubmed.ncbi.nlm.nih.gov/36529419Test -
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المصدر: Revue du Rhumatisme. 89:107-109
مصطلحات موضوعية: Rheumatology, business.industry, Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::afc7f19b63a53cab31167b47acb67befTest
https://doi.org/10.1016/j.rhum.2020.11.007Test -
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المصدر: Joint bone spine. 89(6)
مصطلحات موضوعية: Arthritis, Rheumatoid, Rheumatology, Humans, Dysbiosis, CTLA-4 Antigen, Genetic Predisposition to Disease, Protein Tyrosine Phosphatase, Non-Receptor Type 22, HLA-DRB1 Chains
الوصف: This narrative review gathers current evidence for a contribution of rheumatoid arthritis (RA) HLA-DRB1, PTPN22 and CTLA4 polymorphisms to the gut dysbiosis observed in RA, especially at its onset (transient excess of Prevotella). The gut microbiome contains elements which are 30% heritable, including genera like Bacteroides and Veillonella, and to a lesser extent Prevotella. The first months/year seems a critical period for the selection of a core of microbiota, that should be considered as a second self by the immune system, and tolerized by regulatory T and B cells. Imperfect tolerization may increase the risk of RA following further repeated silent translocations of various gut microorganisms, including Prevotella copri, from gut to joints (fostered by a concurrent loss in gut mucosa of protective bacteria like Faecalibacterium prausnitzii). Genetics studies confirmed that Prevotella copri was partly heritable, and strong associations were observed between the overall microbial composition of stools and the HLA-DRB1 RA risk allele, either in a US cohort (P=0.00001), or the Twins UK cohort (P=0.033). This finding also stands for persons still free from RA, and was replicated in the Swiss SCREEN-RA cohort. Gene variants of PTPN22 also modify intestinal microbiota composition, compromise granulocyte-mediated antibacterial defence in gut, and reduce the suppressive effect of gut regulatory B cells. CTLA4 variants may similarly contribute to RA dysbiosis, since immunotherapy by CTLA-4 blockade depends on microbiota, and CTLA4 activates T follicular regulatory cells to reduce immune responses to segmented filamentous bacteria. Suggestions for future works are made.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c4af7fbf15f516368cd8f205f95370Test
https://pubmed.ncbi.nlm.nih.gov/35940545Test -
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المؤلفون: Jean-Marie Berthelot, Kevin Brulefert, Paul Arnolfo, Benoît Le Goff, Christelle Darrieutort-Laffite
المصدر: Joint bone spine. 90(1)
مصطلحات موضوعية: Rheumatology
الوصف: Hip labral tears are found in 22-55% of individuals with hip pain, but labral tears without cysts are usually not responsible for hip pain, which originates mostly from other structures than the torn labrum, like osteochondral, but also tendinous injuries (rectus femoris, gluteus minimus, iliopsoas) or capsulo-ligamentous tears (iliofemoral ligaments, ligament teres). Those lesions are mainly the consequences of underlying unrecognized functional acetabular dysplasia, and/or femoroacetabular impingements. Although the early repair of labral tears in young sportsmen induces a marked and lasting relief, and might delay the onset of osteoarthritis, the microinstability fostered by labral damages seems less important than underlying dysplasias/impingements. This narrative review details recent findings on: (i) the various mechanisms of pain associated with labral tears; (ii) few evidence for hip microinstability induced by isolated labral tears; (iii) how to best detect labral tears, both clinically (including through IROP test) and on imaging (MRI, MRA, computed tomography arthrography, ultrasound). Some authors suggested to use pull-out tests during surgery, but pulling of hips do not seem to increase much diagnostic performances of ultrasounds. Ultrasound-guided intra-articular and peri-articular injections may tell how often hip pain is exclusively induced by peri-capsular injuries secondary to the acetabular dysplasia/femoro-acetabular impingements already responsible for labral tears. Further works could tell whether labral repair, tendinous debridement, plication of capsule, and/or focal denervation, may induce lasting reliefs of pain induced by the chronic contraction of surrounding muscles (rectus femoris, gluteus minimus, psoas), whose deep aponeuroses mix with the superficial fibres of the thick hip capsule.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595f4fbf57c22212aaf4a799207f5b0eTest
https://pubmed.ncbi.nlm.nih.gov/36150666Test -
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المؤلفون: Pauline Richebé, Guillaume Coiffier, Pascal Guggenbuhl, Denis Mulleman, Marion Couderc, Emanuelle Dernis, Valentine Deprez, Carine Salliot, Saik urien, Rachel Brault, Adeline Ruyssen-Witrand, Emmanuel Hoppe, Emmanuel Chatelus, Christian hubert roux, Sebastien Ottaviani, Marie Baufrere, Alexia Michaut, Loic Pauvele, Christelle Darrieutort-Laffite, Daniel Wendling, Pascal Coquerelle, Géraldine Bart, Elisabeth Gervais, Vincent Goeb, Marc Ardizzone, Edouard Pertuiset, Sophie Derolez, Jean Marc Ziza, René-Marc Flipo, Sophie Godot, Raphaele Seror
المساهمون: Hôpitaux Universitaires Paris-Sud, Centre hospitalier de Dinan, CHU Pontchaillou [Rennes], Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, Centre Hospitalier Le Mans (CH Le Mans), CHU Amiens-Picardie, Service de Rhumatologie [Orléans], Centre Hospitalier Régional d'Orléans (CHRO), CHU Orléans, Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Centre hospitalier universitaire de Poitiers (CHU Poitiers), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Les Hôpitaux Universitaires de Strasbourg (HUS), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Centre hospitalier universitaire de Nantes (CHU Nantes)
المصدر: Annals of the Rheumatic Diseases
Annals of the Rheumatic Diseases, 2022, pp.annrheumdis-2022-222143. ⟨10.1136/ard-2022-222143⟩مصطلحات موضوعية: Rheumatology, [SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal system, Epidemiology, Arthritis, Immunology, Infectious, Immunology and Allergy, General Biochemistry, Genetics and Molecular Biology
الوصف: ObjectivesTo describe current management and outcome of native joint septic arthritis (NJSA) in French rheumatology departments.MethodsFor this retrospective, nationwide multicentric study, 127 French rheumatology departments were contacted to report up to 12 cases of NJSA that occurred between 1 January 2016 and 31 December 2017. Characteristics, diagnosis procedures, therapeutic management and outcome were recorded.ResultsOverall, 362 patients were included (mean age 64.0±18.6 years, median Charlson comorbidity index 3.5 (0–14)). Knee was the most frequent site (n=160 (38.9%)), andStaphylococcussp (n=185 (51.4%)), the most frequent pathogen. All patients received antibiotics for a mean duration of 46.8 (±22.0) days, including intravenous route for a mean of 17.2 (±15.4) days. Management was heterogeneous. Surgical procedure was performed in 171 (48.3%), joint immobilisation in 128 (43.8%). During follow-up, 91 (28.3%) patients have had serious complications and 28 (9.2%) of them died. Factors associated with 1-year mortality were age (OR 1.08, 95% CI 1.04 to 1.13; pStaphylococcus aureusNJSA compared withStreptococcussp. NJSA (OR 7.24, 95% CI 1.26 to 41.68, p=0.027). The complete recovery with no adverse joint outcome at 1 year was observed in n=125/278 patients (55.0%).ConclusionPrognosis of NJSA remained severe with a high rate of morbimortality. Its management was very heterogeneous. This study highlights the importance of the new French recommendations, published after the completion of the study, in order to facilitate NJSA management.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf0f699cbc2f5fd1122d61a11d1ba1eTest
https://pubmed.ncbi.nlm.nih.gov/35820674Test -
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المؤلفون: Robert Touitou, Géraldine Bart, Marion Couderc, E. Veillard, Pascal Guggenbuhl, P. Coquerelle, Sophie Godot, Christian Lormeau, Denis Mulleman, Guillaume Coiffier, Carine Salliot, Marion Baldeyrou, Beate Hyem, Jean-Marc Ziza, Thomas W. Bauer, René-Marc Flipo, Christelle Darrieutort-Laffite, Raphaèle Seror, Bernard Fouquet, Louis Bernard
المساهمون: Imagerie Moléculaire et Stratégies Théranostiques (IMoST), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne (UCA), CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand
المصدر: Joint Bone Spine
Joint Bone Spine, 2020, 87 (6), pp.538-547. ⟨10.1016/j.jbspin.2020.07.012⟩
Joint Bone Spine, Elsevier Masson, 2020, 87 (6), pp.538-547. ⟨10.1016/j.jbspin.2020.07.012⟩مصطلحات موضوعية: Adult, Staphylococcus aureus, medicine.medical_specialty, medicine.drug_class, [SDV]Life Sciences [q-bio], Antibiotics, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Internal medicine, Humans, Medicine, Streptococcus gallolyticus, 030212 general & internal medicine, Medical diagnosis, Intensive care medicine, ComputingMilieux_MISCELLANEOUS, Language, 030203 arthritis & rheumatology, Arthritis, Infectious, business.industry, Staphylococcal Infections, medicine.disease, Anti-Bacterial Agents, 3. Good health, Joint aspiration, Infective endocarditis, Septic arthritis, business, Trauma surgery
الوصف: Septic arthritis (SA) in an adult native joint is a rare condition but a diagnostic emergency due to the morbidity and mortality and the functional risk related to structural damage. Current management varies and the recommendations available are dated. The French Rheumatology Society (SFR) Bone and Joint Infection Working Group, together with the French Language Infectious Diseases Society (SPILF) and the French Orthopaedic and Trauma Surgery Society (SOFCOT) have worked according to the HAS methodology to devise clinical practice recommendations to diagnose and treat SA in an adult native joint. One new focus is on the importance of microbiological documentation (blood cultures and joint aspiration) before starting antibiotic treatment, looking for differential diagnoses (microcrystal detection), the relevance of a joint ultrasound to guide aspiration, and the indication to perform a reference X-ray. A cardiac ultrasound is indicated only in cases of SA involving Staphylococcus aureus, oral streptococci, Streptococcus gallolyticus or Enterococcus faecalis, or when infective endocarditis is clinically suspected. Regarding treatment, we stress the importance of medical and surgical collaboration. Antibiotic therapies (drugs and durations) are presented in the form of didactic tables according to the main bacteria in question (staphylococci, streptococci and gram-negative rods). Probabilistic antibiotic therapy should only be used for patients with serious symptoms. Lastly, non-drug treatments such as joint drainage and early physical therapy are the subject of specific recommendations.
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9308e225fae67b0cbfb68fa506305f5Test
https://doi.org/10.1016/j.jbspin.2020.07.012Test
