المؤلفون: Nagaraj Kerur, S. Michal Jazwinski, John C. Cambier, Katherine A. Fitzgerald, Tetsuhiro Yasuma, Shinichi Fukuda, Vidya L. Ambati, Reo Yasuma, Isao Hara, Jayakrishna Ambati, Srinivas R. Sadda, Ivana Apicella, Tetsuro Oshika, Bradley D. Gelfand, Meenakshi Ambati, Kyung Bo Kim, Elmira Baghdasaryan, Hiroshi Nagai, Yuichiro Ogura, Akhil Varshney, Yuji Kajiwara, Dongxu Fu, Norbert Leitinger, A. Phillip West, Kameshwari Ambati, Yoshio Hirano, Kenneth M. Marion, Daipayan Banerjee, Benjamin J. Fowler, Joseph D. Buxbaum, Vlad Serbulea, Younghee Kim, Hiroko Terasaki, Xiwen Huang, Ana Bastos-Carvalho, David R. Hinton, M. Cristina Kenney, Shuichiro Hirahara

المصدر: Nature medicine

مصطلحات موضوعية: 0301 basic medicine, Ribonuclease III, Inflammasomes, Degeneration (medical), Retinal Pigment Epithelium, Biology, General Biochemistry, Genetics and Molecular Biology, Article, DEAD-box RNA Helicases, 03 medical and health sciences, Mice, 0302 clinical medicine, Interferon, Geographic Atrophy, medicine, Animals, Humans, Secretion, Retina, RNA, Inflammasome, General Medicine, Anatomy, Macular degeneration, medicine.disease, Nucleotidyltransferases, Cell biology, 030104 developmental biology, medicine.anatomical_structure, Interferon Type I, Signal transduction, 030217 neurology & neurosurgery, medicine.drug, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fae00b0f6a316123b3648987eee4baTest
http://europepmc.org/articles/PMC5760363Test

المؤلفون: Gabriel Virella, Junping Chen, Maria F. Lopes-Virella, Mei Du, Yanchun Li, Dongxu Fu, Jian Xing Ma, Jeremy Y. Yu, Michael E. Boulton, Mingyuan Wu, Timothy J. Lyons, Souzan A. Abdelsamie, Ying Chen

المصدر: Journal of Lipid Research. 55:860-869

مصطلحات موضوعية: medicine.medical_specialty, Cell Survival, Receptor expression, CD36, Intracellular Space, Blood–retinal barrier, Apoptosis, Antigen-Antibody Complex, Biology, Immune complex formation, Biochemistry, Retina, chemistry.chemical_compound, Endocrinology, Internal medicine, medicine, Humans, Scavenger receptor, Research Articles, Aged, Receptors, Scavenger, Receptors, IgG, Retinal, Cell Biology, Endoplasmic Reticulum Stress, Capillaries, Lipoproteins, LDL, Protein Transport, medicine.anatomical_structure, Diabetes Mellitus, Type 2, chemistry, Immunoglobulin G, biology.protein, Cytokines, lipids (amino acids, peptides, and proteins), Cytokine secretion, Pericytes, Reactive Oxygen Species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a191b841f412a39c4342d4e581e8d927Test
https://doi.org/10.1194/jlr.m045401Test

المؤلفون: Arpita Basu, Jeremy Y. Yu, Timothy J. Lyons, Christopher E. Aston, Mingyuan Wu, Jian Xing Ma, Michael H. Elliott, Dongxu Fu, Mei Du, Xiaowu Gu, Shihe Yang

المصدر: Yu, J Y, Du, M, Elliott, M H, Wu, M, Fu, D, Yang, S, Basu, A, Gu, X, Ma, J-X, Aston, C E & Lyons, T J 2016, ' Extravascular modified lipoproteins: a role in the propagation of diabetic retinopathy in a mouse model of type 1 diabetes ', Diabetologia, vol. 59, no. 9, pp. 2026-2035 . https://doi.org/10.1007/s00125-016-4012-6Test
Diabetologia

مصطلحات موضوعية: 0301 basic medicine, Plasma lipoprotein, Male, medicine.medical_specialty, Dyslipidaemia, Endocrinology, Diabetes and Metabolism, Pathogenesis, Article, Oxidised LDL, Diabetes Mellitus, Experimental, 03 medical and health sciences, Mice, 0302 clinical medicine, SDG 3 - Good Health and Well-being, Glycation, Internal medicine, medicine, Electroretinography, Internal Medicine, Animals, Humans, Lipoprotein, Type 1 diabetes, Retina, Diabetic Retinopathy, medicine.diagnostic_test, business.industry, Vascular complications, Diabetic retinopathy, medicine.disease, 3. Good health, Lipoproteins, LDL, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Diabetes Mellitus, Type 1, 030221 ophthalmology & optometry, lipids (amino acids, peptides, and proteins), business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf874f0eaf00a399bcdf533e730a4b6Test
https://pure.qub.ac.uk/en/publications/extravascular-modified-lipoproteins-a-role-in-the-propagation-of-diabetic-retinopathy-in-a-mouse-model-of-type-1-diabetesTest(95420eeb-3ba3-4d88-8713-d9f68bd56296).html

المؤلفون: Kenneth Wilson, Junping Chen, Shihe Yang, Timothy J. Lyons, Mingyuan Wu, Mei Du, Dongxu Fu

مصطلحات موضوعية: Glycation End Products, Advanced, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 030209 endocrinology & metabolism, Apoptosis, In Vitro Techniques, medicine.disease_cause, Article, Retina, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Autophagy, Humans, Cells, Cultured, 030304 developmental biology, 0303 health sciences, Diabetic Retinopathy, business.industry, Retinal, Diabetic retinopathy, medicine.disease, Endoplasmic Reticulum Stress, Extravasation, 3. Good health, Lipoproteins, LDL, Oxidative Stress, medicine.anatomical_structure, Endocrinology, chemistry, lipids (amino acids, peptides, and proteins), sense organs, business, Lipoproteins, HDL, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46e9480bdaa69f6084fe36be9ae56bdTest
https://europepmc.org/articles/PMC4557884Test/

المؤلفون: Junping Chen, Dongxu Fu, Junhua Zhang, Timothy J. Lyons, Mei Du, Mingyuan Wu, Samar M. Hammad, Shihe Yang, Kenneth Wilson

المصدر: Diabetologia. 55(11)

مصطلحات موضوعية: medicine.medical_specialty, Glycosylation, Cell Survival, Endocrinology, Diabetes and Metabolism, Apoptosis, Biology, medicine.disease_cause, Butylamines, Retina, Article, Acetylcysteine, Internal medicine, Ophthalmology, Internal Medicine, medicine, Autophagy, Humans, Enzyme Inhibitors, Endoplasmic Reticulum Chaperone BiP, Cells, Cultured, Heat-Shock Proteins, Apolipoproteins B, Modified ldl, Diabetic Retinopathy, Retinal Vessels, Diabetic retinopathy, Retinal injury, medicine.disease, Endoplasmic Reticulum Stress, Activating Transcription Factor 6, Mitochondria, Lipoproteins, LDL, Oxidative Stress, Endocrinology, medicine.anatomical_structure, Poly I, Cyclosporine, lipids (amino acids, peptides, and proteins), Pericyte, Lipid Peroxidation, Pericytes, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1daaf544f9653c2dbe4b84c347689fTest
https://pubmed.ncbi.nlm.nih.gov/22935961Test

المؤلفون: Timothy J. Lyons, Dongxu Fu, Junping Chen, Anna R. Connell, Samar M. Hammad, Shihe Yang, Mingyuan Wu, Mei Du, Jeremy Y. Yu

المصدر: Diabetologia
Fu, D, Yu, J Y, Yang, S, Wu, M, Hammad, S M, Connell, A R, Du, M, Chen, J & Lyons, T J 2016, ' Survival or death: a dual role of autophagy in stress-induced pericyte loss in diabetic retinopathy ', Diabetologia, vol. 59, no. 10, pp. 2251-2261 . https://doi.org/10.1007/s00125-016-4058-5Test

مصطلحات موضوعية: 0301 basic medicine, Glycation End Products, Advanced, Endocrinology, Diabetes and Metabolism, Apoptosis, medicine.disease_cause, Amino Acid Chloromethyl Ketones, Mice, 0302 clinical medicine, Diabetic retinopathy, LC3B, Endoplasmic Reticulum Stress, Immunohistochemistry, Extravasation, 3. Good health, Lipoproteins, LDL, medicine.anatomical_structure, Beclin-1, Pericyte, ER stress, Oxidation-Reduction, Apoptosis . Autophagy . Diabetic retinopathy, medicine.medical_specialty, Cell Survival, MAP Kinase Signaling System, Retina, Article, 03 medical and health sciences, Dual role, SDG 3 - Good Health and Well-being, Internal medicine, medicine, Autophagy, Internal Medicine, Animals, Humans, Modified LDL, business.industry, Adenine, medicine.disease, Oxidative Stress, 030104 developmental biology, Endocrinology, 030221 ophthalmology & optometry, Unfolded protein response, business, Pericytes, Oxidative stress, Transcription Factor CHOP

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a829bccefe1bd67b38783d72b1e541b3Test