المؤلفون: Catherine John, Anna L. Guyatt, Nick Shrine, Richard Packer, Thorunn A. Olafsdottir, Jiangyuan Liu, Lystra P. Hayden, Su H. Chu, Jukka T. Koskela, Jian’an Luan, Xingnan Li, Natalie Terzikhan, Hanfei Xu, Traci M. Bartz, Hans Petersen, Shuguang Leng, Steven A. Belinsky, Aivaras Cepelis, Ana I. Hernández Cordero, Ma’en Obeidat, Gudmar Thorleifsson, Deborah A. Meyers, Eugene R. Bleecker, Lori C. Sakoda, Carlos Iribarren, Yohannes Tesfaigzi, Sina A. Gharib, Josée Dupuis, Guy Brusselle, Lies Lahousse, Victor E. Ortega, Ingileif Jonsdottir, Don D. Sin, Yohan Bossé, Maarten van den Berge, David Nickle, Jennifer K. Quint, Ian Sayers, Ian P. Hall, Claudia Langenberg, Samuli Ripatti, Tarja Laitinen, Ann C. Wu, Jessica Lasky-Su, Per Bakke, Amund Gulsvik, Craig P. Hersh, Caroline Hayward, Arnulf Langhammer, Ben Brumpton, Kari Stefansson, Michael H. Cho, Louise V. Wain, Martin D. Tobin

المساهمون: University of Helsinki, Institute for Molecular Medicine Finland, Faculty Common Matters (Faculty of Social Sciences), Department of Public Health, Centre of Excellence in Complex Disease Genetics, Samuli Olli Ripatti / Principal Investigator, Complex Disease Genetics, Groningen Research Institute for Asthma and COPD (GRIAC), Epidemiology

المصدر: John, C, Guyatt, A L, Shrine, N, Packer, R, Olafsdottir, T A, Liu, J, Hayden, L P, Chu, S H, Koskela, J T, Luan, J, Li, X, Terzikhan, N, Xu, H, Bartz, T M, Petersen, H, Leng, S, Belinsky, S A, Cepelis, A, Hernández Cordero, A I, Obeidat, M, Thorleifsson, G, Meyers, D A, Bleecker, E R, Sakoda, L C, Iribarren, C, Tesfaigzi, Y, Gharib, S A, Dupuis, J, Brusselle, G, Lahousse, L, Ortega, V E, Jonsdottir, I, Sin, D D, Bossé, Y, van den Berge, M, Nickle, D, Quint, J K, Sayers, I, Hall, I P, Langenberg, C, Ripatti, S, Laitinen, T, Wu, A C, Lasky-Su, J, Bakke, P, Gulsvik, A, Hersh, C P, Hayward, C, Langhammer, A, Brumpton, B, Stefansson, K, Cho, M H, Wain, L V & Tobin, M D 2022, ' Genetic Associations and Architecture of Asthma-COPD Overlap ', Chest Journal, vol. 161, no. 5, pp. 1155-1166 . https://doi.org/10.1016/j.chest.2021.12.674Test
Chest, 161(5), 1155-1166. ELSEVIER SCIENCE BV
Chest, 161(5), 1155-1166. American College of Chest Physicians

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, HAY-FEVER, Pulmonary Disease, Chronic Obstructive/complications, Smoking/genetics, Respiratory System, spirometry, LOCI, Asthma/diagnosis, Critical Care and Intensive Care Medicine, OBSTRUCTIVE PULMONARY-DISEASE, Pulmonary Disease, Chronic Obstructive, BLOOD EOSINOPHIL COUNT, immune system diseases, Humans, COPD, GENOME-WIDE ASSOCIATION, Lung, RISK, genome-wide association study, HERITABILITY, Smoking, 1103 Clinical Sciences, asthma, 3126 Surgery, anesthesiology, intensive care, radiology, respiratory tract diseases, EXACERBATIONS, 3121 General medicine, internal medicine and other clinical medicine, epidemiology, Cardiology and Cardiovascular Medicine, Genome-Wide Association Study

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c8fb091c961670f203a75c6b7a2546Test
http://hdl.handle.net/10138/347934Test

المؤلفون: David O. Bates, Vincent Pang, Judith M. Vonk, Charlote K. Billington, John W. Holloway, Sangita Bhaker, Cornelis J. Vermeulen, Don D. Sin, Ian Sayers, Martin D. Tobin, Peter H. Howarth, F. Nicole Dijk, David C. Nickle, Ian P. Hall, Yohan Bossé, Louise V. Wain, Dominick E. Shaw, John D Blakey, Andrew M. Fogarty, Amisha Singapuri, Michael A. Portelli, Martijn C. Nawijn, Cheng J. Xu, Andrew V. Benest, Ma'en Obeidat, Liam G Heaney, Jenny Hankinson, Maarten van den Berge, Rekha Chaudhuri, Angela Simpson, Tricia M. McKeever, Simon R. Johnson, Adel H. Mansur, Robert Niven, Zara Pogson, Gabrielle A. Lockett, Christopher E. Brightling, Amanda P. Henry, Neil C. Thomson, Nick Shrine, Gerard H. Koppelman, Maria Ketelaar, Alen Faiz

المساهمون: Groningen Research Institute for Asthma and COPD (GRIAC)

المصدر: Journal of Allergy and Clinical Immunology, 147(1), 144-157. MOSBY-ELSEVIER

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Immunology, asthma phenotypes, Genome-wide association study, Single-nucleotide polymorphism, eQTL, IL33 SNPs, functional translation, Polymorphism, Single Nucleotide, Atopy, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Immunology and Allergy, Eosinophilia, Genetic Predisposition to Disease, Asthma, bronchial epithelium, Genetics, House dust mite, biology, business.industry, Middle Aged, respiratory system, Interleukin-33, medicine.disease, biology.organism_classification, respiratory tract diseases, 030104 developmental biology, Gene Expression Regulation, 030228 respiratory system, Expression quantitative trait loci, Sputum, Female, medicine.symptom, business, Genome-Wide Association Study

وصف الملف: text; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2e19b5c3a77f7d0087040f985a7c81Test
https://doi.org/10.1016/j.jaci.2020.04.051Test

المؤلفون: Alison D. Murray, Anna L. Guyatt, Jing Hua Zhao, Eugene R. Bleecker, Matthias Wielscher, Frank Dudbridge, Martin D. Tobin, Veronique Vitart, Ida Surakka, Nadia N. Hansel, Ozren Polasek, Caroline Hayward, David P. Strachan, Per Bakke, Stefan Karrasch, Anubha Mahajan, James F. Wilson, Shona M. Kerr, Ruth Tal-Singer, James D. Crapo, Victoria E. Jackson, Jonathan Marten, Olli T. Raitakari, María Soler Artigas, Medea Imboden, Sungho Won, Beate Stubbe, Ulf Gyllensten, George R. Washko, Eleftheria Zeggini, David A. Lynch, Brian D. Hobbs, Matthew Moll, Mika Kähönen, Rajesh Rawal, Guy Brusselle, Ma'en Obeidat, Nicholas J. Wareham, Claudia Langenberg, Nicole Probst-Hensch, Peter K. Joshi, Blair H. Smith, Stefan Weiss, Woo Jin Kim, Kathleen C. Barnes, Sarah E. Harris, David J. Porteous, Stefan Enroth, Ian P. Hall, Alan L. James, Sina A. Gharib, Paul R. H. J. Timmers, Xingnan Li, Louise V. Wain, John E. Hokanson, Holger Schulz, Ralf Ewert, Ani Manichaikul, Lies Lahousse, Georg Homuth, R. Graham Barr, Scott T. Weiss, Phuwanat Sakornsakolpat, Sara R.A. Wijnant, Edwin K. Silverman, Christian Gieger, Jennie Hui, Andrew P. Morris, James P. Cook, Michael J. McGeachie, Dawn L. DeMeo, Nick Shrine, Traci M. Bartz, Amund Gulsvik, Deborah A. Meyers, Katherine A. Kentistou, Igor Rudan, Jian'an Luan, Ian J. Deary, Catherine John, Michael H. Cho, Lars Lind, Marjo-Riitta Järvelin, Ah Ra Do, Terho Lehtimäki, Stephen S. Rich, Bruce M. Psaty

المساهمون: Tampere University, Department of Clinical Physiology and Nuclear Medicine, Clinical Medicine, Department of Clinical Chemistry, Epidemiology, Pulmonary Medicine

المصدر: The Lancet. Respiratory Medicine
Moll, M, Sakornsakolpat, P, Shrine, N, Hobbs, B D, DeMeo, D L, John, C, Guyatt, A L, McGeachie, M J, Gharib, S A, Obeidat, M, Lahousse, L, Wijnant, S R A, Brusselle, G, Meyers, D A, Bleecker, E R, Li, X, Tal-Singer, R, Manichaikul, A, Rich, S S, Won, S, Kim, W J, Do, A R, Washko, G R, Barr, R G, Psaty, B M, Bartz, T M, Hansel, N N, Barnes, K, Hokanson, J E, Crapo, J D, Lynch, D, Bakke, P, Gulsvik, A, Hall, I P, Wain, L, Soler Artigas, M, Jackson, V E, Strachan, D P, Hui, J, James, A L, Kerr, S M, Polasek, O, Vitart, V, Marten, J, Rudan, I, Kähönen, M, Surakka, I, Gieger, C, Karrasch, S, Rawal, R, Schulz, H, Deary, I J, Harris, S E, Enroth, S, Gyllensten, U, Imboden, M, Probst-Hensch, N M, Lehtimäki, T, Raitakari, O T, Langenberg, C, Luan, J, Wareham, N, Zhao, J H, Hayward, C, Murray, A, Porteous, D J, Smith, B H, Jarvelin, M R, Wielscher, M, Joshi, P K, Kentistou, K A, Timmers, P RHJ, Wilson, J F, Cook, J P, Lind, L, Mahajan, A, Morris, A P, Ewert, R, Homuth, G, Stubbe, B, Weiss, S, Zeggini, E, Weiss, S T, Silverman, E K, Dudbridge, F, Tobin, M D & Cho, M H 2020, ' Chronic obstructive pulmonary disease and related phenotypes : polygenic risk scores in population-based and case-control cohorts ', The Lancet Respiratory Medicine, vol. 8, no. 7, pp. 696-708 . https://doi.org/10.1016/S2213-2600Test(20)30101-6
LANCET RESPIRATORY MEDICINE
Lancet Resp. Med. 8, 696-708 (2020)
The Lancet Respiratory Medicine, 8(7), 696-708. Elsevier Ltd.

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, AMERICAN THORACIC SOCIETY, Vital Capacity, LOCI, Genome-wide association study, EMPHYSEMA, Cohort Studies, 03 medical and health sciences, FEV1/FVC ratio, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Risk Factors, Internal medicine, Forced Expiratory Volume, adult, case-control studies, cohort studies, female, forced expiratory volume, genome-wide association study, humans, male, middle aged, phenotype, pulmonary disease, chronic obstructive, risk factors, vital capacity, Medicine and Health Sciences, medicine, COPD, Humans, SMOKING-BEHAVIOR, 030212 general & internal medicine, GENOME-WIDE ASSOCIATION, FAMILIAL AGGREGATION, GENETIC EPIDEMIOLOGY, Framingham Risk Score, HERITABILITY, business.industry, Case-control study, Family aggregation, Odds ratio, Articles, Middle Aged, medicine.disease, respiratory tract diseases, LUNG-FUNCTION, Phenotype, 030228 respiratory system, Genetic epidemiology, Case-Control Studies, Female, 3111 Biomedicine, business, Genome-Wide Association Study

وصف الملف: application/pdf; fulltext

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::843f5a24714e2e558b0402f729db9de8Test
http://europepmc.org/articles/PMC7429152Test

المؤلفون: Jonathan Brooke, J K Baillie, Mark Weeks, A. John Simpson, Laura Fabbri, Ian P. Hall, Daniel G. Wootton, Toby Hillman, R. Gisli Jenkins, Jim M. Wild, Rod Lawson, Mark Spears, A. A. Roger Thompson, Jennifer K Quint, Guilhem Collier, Louise V. Wain, Simon R. Johnson, Manuela Platé, Ling-Pei Ho, Karen Piper Hanley, Simon L.F. Walsh, Neil A. Hanley, Melissa Heightman, Malcolm G Semple, Raminder Aul, Rachel C. Chambers, Joanna C. Porter, Nazia Chaudhuri, Fergus V. Gleeson, Nicholas D Weatherley, Paul Beirne, Emma K Denneny, Philip L. Molyneaux, Christopher E. Brightling, Joseph Jacob, Jane A. Mitchell, Richard J. Allen, Lisa G. Spencer, D. J. F. Smith, Stephen Bianchi, Michael A Gibbons, Pilar Rivera-Ortega, Mark G. Jones, David R Thickett, Peter M. George, John F. Blaikley, Iain A. Stewart, Bibek Gooptu, Stefan C. Stanel, Annemarie B Docherty, Krisnah Poinasamy, Fasihul Khan, Puja Mehta, Shaney L Barratt

المصدر: Wild, J M, Porter, J C, Molyneaux, P L, George, P M, Stewart, I, Allen, R J, Aul, R, Baillie, J K, Barratt, S L, Beirne, P, Bianchi, S M, Blaikley, J F, Brooke, J, Chaudhuri, N, Collier, G, Denneny, E K, Docherty, A, Fabbri, L, Gibbons, M A, Gleeson, F V, Gooptu, B, Hall, I P, Hanley, N A, Heightman, M, Hillman, T E, Johnson, S R, Jones, M G, Khan, F, Lawson, R, Mehta, P, Mitchell, J A, Platé, M, Poinasamy, K, Quint, J K, Rivera-Ortega, P, Semple, M, Simpson, A J, Smith, D, Spears, M, Spencer, LI G, Stanel, S C, Thickett, D R, Thompson, A A R, Walsh, S L, Weatherley, N D, Weeks, M E, Wootton, D G, Brightling, C E, Chambers, R C, Ho, L-P, Jacob, J, Piper Hanley, K, Wain, L V & Jenkins, R G 2021, ' Understanding the burden of interstitial lung disease post-COVID-19 : the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) ', BMJ Open Respiratory Research, vol. 8, no. 1 . https://doi.org/10.1136/bmjresp-2021-001049Test
BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Wild, J M, Porter, J C, Molyneaux, P L, George, P M, Stewart, I, Allen, R J, Aul, R, Baillie, J K, Barratt, S L, Beirne, P, Bianchi, S M, Blaikley, J F, Brooke, J, Chaudhuri, N, Collier, G, Denneny, E K, Docherty, A, Fabbri, L, Gibbons, M A, Gleeson, F V, Gooptu, B, Hall, I P, Hanley, N A, Heightman, M, Hillman, T E, Johnson, S R, Jones, M G, Khan, F, Lawson, R, Mehta, P, Mitchell, J A, Platé, M, Poinasamy, K, Quint, J K, Rivera-Ortega, P, Semple, M, Simpson, A J, Smith, D, Spears, M, Spencer, LI G, Stanel, S C, Thickett, D R, Thompson, A A R, Walsh, S L, Weatherley, N D, Weeks, M E, Wootton, D G, Brightling, C E, Chambers, R C, Ho, L-P, Jacob, J, Piper Hanley, K, Wain, L V & Jenkins, R G 2021, ' Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID) ', BMJ Open Respiratory Research, vol. 8, no. 1, e001049 . https://doi.org/10.1136/bmjresp-2021-001049Test

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, medicine.medical_specialty, bronchoscopy, Respiratory System, Diseases of the respiratory system, Post-Acute COVID-19 Syndrome, Bronchoscopy, Pandemic, medicine, Humans, Longitudinal Studies, Prospective Studies, Intensive care medicine, Prospective cohort study, Pandemics, Lung, Science & Technology, medicine.diagnostic_test, RC705-779, business.industry, Interstitial lung disease, COVID-19, interstitial fibrosis, respiratory system, medicine.disease, United Kingdom, respiratory tract diseases, Observational Studies as Topic, Bronchoalveolar lavage, medicine.anatomical_structure, Medicine, Observational study, business, Lung Diseases, Interstitial, Life Sciences & Biomedicine

وصف الملف: application/pdf; text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f277393c18d7f4508070abaaf9e8806eTest
https://hdl.handle.net/20.500.11820/49b19f77-85af-48c9-b2d6-164c21ea8b44Test

المؤلفون: Ian P. Hall, Irwin Nazareth, Laura Horsfall

المصدر: Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Respiratory Research

مصطلحات موضوعية: Adult, Male, Oncology, medicine.medical_specialty, Lung Neoplasms, Time Factors, Diseases of the respiratory system, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Mendelian randomization, Biomarkers, Tumor, medicine, Humans, Registries, 030212 general & internal medicine, Risk factor, Lung cancer, Urate, Aged, COPD, RC705-779, business.industry, Research, Incidence, Incidence (epidemiology), Confounding, Causal relationship, Cancer, Mendelian Randomization Analysis, Middle Aged, medicine.disease, United Kingdom, Lung function, Uric Acid, respiratory tract diseases, 3. Good health, Smoking phenotypes, 030220 oncology & carcinogenesis, Female, business, Follow-Up Studies, Cohort study

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b7865de273f108331b0b57f6f87dc4Test
https://doi.org/10.1186/s12931-021-01768-yTest

المؤلفون: Phuwanat Sakornsakolpat, James F. Wilson, María Soler Artigas, Beate Stubbe, Nicholas J. Wareham, James D. Crapo, Victoria E. Jackson, Eleftheria Zeggini, Olga G. Troyanskaya, Medea Imboden, A. Mesut Erzurumluoglu, Adam S. Butterworth, Carl A. Melbourne, Ian Sayers, Lars Lind, Stefan Weiss, Margaret M. Parker, Timmers Prhj, Edwin K. Silverman, John C. Whittaker, Ian P. Hall, Ozren Polasek, Mika Kähönen, Katherine A. Fawcett, Anna Hansell, Liming Li, David J. Porteous, Louise V. Wain, Robert A. Scott, Richard Packer, Richard J. Allen, Robin G Walters, Anna L. Guyatt, Terho Lehtimäki, Nicole Probst-Hensch, Shona M. Kerr, Christian Gieger, Matthias Wielscher, Rajesh Rawal, Jing Hua Zhao, John E. Hokanson, Holger Schulz, Nicola F. Reeve, Claudia Langenberg, Ke Hao, Corry-Anke Brandsma, Megan L. Paynton, Vitart, Dmitry Prokopenko, Jennie Hui, Eugene R. Bleecker, Ma'en Obeidat, John Danesh, Ralf Ewert, Benjamin B. Sun, Frank Dudbridge, Jian Zhou, Brian D. Hobbs, Blair H. Smith, Don D. Sin, Dawn L. DeMeo, Joseph C. Maranville, Ida Surakka, Alison Catherine Murray, Nicholas Locantore, Katherine A. Kentistou, Terri H. Beaty, Igor Rudan, Kuang Lin, Amund Gulsvik, Ian J. Deary, Ruth Tal-Singer, Kijoung Song, David C. Nickle, Michael H. Cho, Jian'an Luan, Joshua D. Hoffman, Georg Homuth, Zhengming Chen, Dandi Qiao, Heiko Runz, Per Bakke, Chiara Batini, Caroline Hayward, Stefan Karrasch, Alan James, Andrew P. Morris, Prescott G. Woodruff, Laura M Yerges Armstrong, David Sparrow, Ulf Gyllensten, James P. Cook, Jonathan Marten, Olli T. Raitakari, Nick Shrine, Deborah A. Meyers, Tobin, Ruth Boxall, Marjo-Riitta Järvelin, David P. Strachan, Sarah E. Harris, Philippe Joubert, Stefan Enroth, Xingnan Li, van den Berge M, Anubha Mahajan, Yohan Bossé, Peter K. Joshi

المساهمون: Shrine, Nick [0000-0003-3641-4371], Guyatt, Anna L [0000-0003-1860-6337], Hobbs, Brian D [0000-0001-9564-0745], Sakornsakolpat, Phuwanat [0000-0002-4308-0974], Obeidat, Ma'en [0000-0002-5443-2752], Weiss, Stefan [0000-0002-3553-4315], Kentistou, Katherine A [0000-0002-5816-664X], Sun, Benjamin B [0000-0001-6347-2281], Enroth, Stefan [0000-0002-5056-9137], Vitart, Veronique [0000-0002-4991-3797], Allen, Richard J [0000-0002-8450-3056], Beaty, Terri H [0000-0002-7644-1705], Bossé, Yohan [0000-0002-3067-3711], Joshi, Peter K [0000-0002-6361-5059], Mahajan, Anubha [0000-0001-5585-3420], Murray, Alison [0000-0003-4915-4847], Porteous, David J [0000-0003-1249-6106], Sayers, Ian [0000-0001-5601-5410], Smith, Blair H [0000-0002-5362-9430], Tal-Singer, Ruth [0000-0002-5275-8062], Timmers, Paul RHJ [0000-0002-5197-1267], Troyanskaya, Olga G [0000-0002-5676-5737], Rudan, Igor [0000-0001-6993-6884], Wilson, James F [0000-0001-5751-9178], Zeggini, Eleftheria [0000-0003-4238-659X], Hayward, Caroline [0000-0002-9405-9550], Morris, Andrew P [0000-0002-6805-6014], Butterworth, Adam S [0000-0002-6915-9015], Walters, Robin G [0000-0002-9179-0321], Cho, Michael H [0000-0002-4907-1657], Strachan, David P [0000-0001-7854-1366], Tobin, Martin D [0000-0002-3596-7874], Wain, Louise V [0000-0003-4951-1867], Apollo - University of Cambridge Repository, Institute for Molecular Medicine Finland, Groningen Research Institute for Asthma and COPD (GRIAC), UNIVERSITY OF OULU, Commission of the European Communities

المصدر: Nature genetics
Nat. Genet. 51, 481-493 (2019)
Shrine, N R G, Guyatt, A, Erzurumluoglu, A M, Jackson, V E, Hobbs, B D, Melbourne, C, Batini, C, Fawcett, K A, Song, K, Sakornsakolpat, P, Li, X, Boxall, R, Reeve, N F, Obeidat, M, Zhao, J H, Wielscher, M, Weiss, S, Kentistou, K, Cook, J P, Sun, B B, Zhou, J, Hui, J, Karrasch, S, Imboden, M, Harris, S, Marten, J, Enroth, S, Kerr, S, Surakka, I, Vitart, V, Lehtimäki, T, Allen, R J, Bakke, P S, Beaty, T H, Bleecker, E R, Bossé, Y, Brandsma, C-A, Chen, Z, Crapo, J D, Danesh, J, Demeo, D L, Dudbridge, F, Ewert, R, Gieger, C, Gulsvik, A, Hansell, A L, Hao, K, Hoffman, J D, Hokanson, J E, Homuth, G, Joshi, P, Joubert, P, Langenberg, C, Li, X, Li, L, Lin, K, Lind, L, Locantore, N, Luan, J, Mahajan, A, Maranville, J C, Murray, A, Nickle, D C, Packer, R, Parker, M M, Paynton, M L, Porteous, D, Prokopenko, D, Qiao, D, Rawal, R, Runz, H, Sayers, I, Sin, D D, Smith, B H, Soler Artigas, M, Sparrow, D, Tal-Singer, R, Timmers, P RHJ, van den Berge, M, Woodruff, P G, Yerges-Armstrong, L M, Troyanskaya, O G, Raitakar, O, Kähönen, M, Polasek, O, Rudan, I, Deary, I, Probst-Hensch, N M, Schulz, H, James, A L, Wilson, J F, Stubbe, B, Zeggini, E, Jarvelin, M-R, Wareham, N, Silverman, E K, Hayward, C, Morris, A P, Butterworth, A S, Scott, R A, Walters, R G, Meyers, D A, Cho, M H, Strachan, D P, Hall, I P & Tobin, M D & Wain, L V 2019, ' New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, pp. 481–493 . https://doi.org/10.1038/s41588-018-0321-7Test
NATURE GENETICS
Understanding Society Scientific Group 2019, ' New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries ', Nature Genetics, vol. 51, no. 3, pp. 481-493 . https://doi.org/10.1038/s41588-018-0321-7Test
Nature Genetics, 51(3), 481-493. Nature Publishing Group

مصطلحات موضوعية: Male, Smoking/genetics, LOCI, Genome-wide association study, VARIANTS, Bioinformatics, Genome-wide association studies, Pulmonary Disease, Chronic Obstructive, 0302 clinical medicine, Polymorphism (computer science), Risk Factors, GWAS, GENOME-WIDE ASSOCIATION, HERITABILITY, COPD, Lung, 11 Medical and Health Sciences, Genetics & Heredity, Aged, 80 and over, 0303 health sciences, Genetic Predisposition to Disease/genetics, Smoking, 1184 Genetics, developmental biology, physiology, Middle Aged, Polymorphism, Single Nucleotide/genetics, 3. Good health, medicine.anatomical_structure, Meta-analysis, Genome-Wide Association Study/methods, Medical genetics, Female, Life Sciences & Biomedicine, medicine.medical_specialty, Understanding Society Scientific Group, Biology, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Genetics, medicine, Humans, Genetic Predisposition to Disease, 030304 developmental biology, Genetic association, Aged, Respiratory tract diseases, Science & Technology, Case-control study, Lung/physiopathology, 06 Biological Sciences, medicine.disease, Pulmonary Disease, Chronic Obstructive/genetics, respiratory tract diseases, Case-Control Studies, 3111 Biomedicine, 030217 neurology & neurosurgery, Developmental Biology, Genome-Wide Association Study

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf; application/x-zip-compressed

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3456e2384a4251ad8956ff4aa355ecc3Test
http://europepmc.org/articles/PMC6397078Test

المؤلفون: Jennifer K Quint, S. Leng, I. Jonsdottir, Tarja Laitinen, Amund Gulsvik, Natalie Terzikhan, Yohan Bossé, Caroline Hayward, Steven A. Belinsky, Ben Michael Brumpton, Hans Petersen, Xingnan Li, Victor E. Ortega, Richard Packer, C. Langenberg, Eugene R. Bleecker, Per Bakke, Ma'en Obeidat, Ian Sayers, A. Cepelis, Josée Dupuis, G. Thorleifsson, Martin D. Tobin, Yohannes Tesfaigzi, Lies Lahousse, Samuli Ripatti, Lystra P. Hayden, A. I. Hernandez Cordero, Carlos Iribarren, Jukka Koskela, Ian P. Hall, S.H. Chu, Sina A. Gharib, T.A. Olafsdottir, Louise V. Wain, Deborah A. Meyers, Catherine John, Craig P. Hersh, Anna L. Guyatt, Michael H. Cho, Ann Chen Wu, Guy Brusselle, David C. Nickle, Don D. Sin, M. van den Berge, Arnulf Langhammer, Jiangyuan Liu, Lori C. Sakoda, Nick Shrine, Jessica Lasky-Su, Traci M. Bartz, Hanfei Xu, K. Stefansson, Jian'an Luan

مصطلحات موضوعية: 0303 health sciences, medicine.medical_specialty, COPD, business.industry, Pulmonary disease, medicine.disease, Biobank, Signal on, Genetic architecture, respiratory tract diseases, 3. Good health, Asthma chronic, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Internal medicine, medicine, business, Lung function, 030304 developmental biology, Asthma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::980eea24082bec7537ef605bf4743b6eTest
https://doi.org/10.1101/2020.11.26.20236760Test

المؤلفون: Victor E. Ortega, Anna L. Guyatt, Ann Chen Wu, Eugene R. Bleecker, Nick Shrine, Jessica Lasky-Su, Jukka Koskela, Thorunn Asta Olafsdottir, Traci M. Bartz, Samuli Ripatti, Deborah A. Meyers, Ian P. Hall, Caroline Hayward, Natalie Terzikhan, Sina A. Gharib, Lystra P. Hayden, Ben Michael Brumpton, Lies Lahousse, Louise V. Wain, Shuguang Leng, Kari Stefansson, Catherine John, Michael H. Cho, Carlos Iribarren, Josée Dupuis, Yohannes Tesfaigzi, Tarja Laitinen, Hanfei Xu, Claudia Langenberg, Hans Petersen, Su H. Chu, Ian Sayers, Martin D. Tobin, Gudmar Thorleifsson, Xingnan Li, Ingileif Jonsdottir, Arnulf Langhammer, Jian'an Luan, Jiangyuan Liu, Lori C. Sakoda

المصدر: Genes and environment.

مصطلحات موضوعية: COPD, medicine.medical_specialty, business.industry, Genetic variants, Genome-wide association study, Overlap syndrome, medicine.disease, Biobank, respiratory tract diseases, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, 030228 respiratory system, Internal medicine, medicine, 030212 general & internal medicine, Asthma copd overlap, business, Lung function, Asthma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bdc6845ba55a37fbaa52800632425c43Test
https://doi.org/10.1183/13993003.congress-2020.4919Test

المؤلفون: Alexander T. Williams, Catherine John, Nicola F. Reeve, Nuala A. Sheehan, Martin D. Tobin, Nick Shrine, Frank Dudbridge, Ian P. Hall, Louise V. Wain, Anna L. Guyatt

مصطلحات موضوعية: COPD, business.industry, Respiratory disease, Disease, respiratory system, Eosinophil, medicine.disease, respiratory tract diseases, FEV1/FVC ratio, medicine.anatomical_structure, Immunology, Mendelian randomization, Medicine, Respiratory system, business, Asthma

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34e38abba08b94a58d12413dc076192aTest
https://doi.org/10.1101/2020.07.09.20148726Test

المؤلفون: Charlotte K. Billington, Gerard H. Koppelman, Liam G Heaney, Adel H. Mansur, Jenny Hankinson, Martijn C. Nawijn, Corry-Anke Brandsma, Sangita Bhaker, Andrew M. Fogarty, Dominick E. Shaw, Michael A. Portelli, Cornelis J. Vermeulen, Judith M. Vonk, Nick Shrine, Amanda P. Henry, Ian Sayers, Yohan Bossé, Maria Ketelaar, Martin D. Tobin, Peter H. Howarth, David C. Nickle, Néomi S. Grotenboer, Ma'en Obeidat, Gabrielle A. Lockett, John W. Holloway, Christopher E. Brightling, Alen Faiz, Rekha Chaudhuri, Tricia M. McKeever, Simon R. Johnson, Paul de Vos, Dirkje S. Postma, Zara Pogson, Neil C. Thomson, Sharon Brouwer, Maarten van den Berge, Angela Simpson, Amisha Singapuri, Robert Niven, F. Nicole Dijk, Ian P. Hall, Louise V. Wain, John D Blakey

المساهمون: Groningen Research Institute for Asthma and COPD (GRIAC), Translational Immunology Groningen (TRIGR), Man, Biomaterials and Microbes (MBM)

المصدر: Portelli, M A, Dijk, F N, Ketelaar, M E, Shrine, N, Hankinson, J, Bhaker, S, Grotenboer, N S, Obeidat, M, Henry, A P, Billington, C K, Shaw, D, Johnson, S R, Pogson, Z E, Fogarty, A, McKeever, T M, Nickle, D C, Bossé, Y, van den Berge, M, Faiz, A, Brouwer, S, Vonk, J M, de Vos, P, Brandsma, C-A, Vermeulen, C J, Singapuri, A, Heaney, L G, Mansur, A H, Chaudhuri, R, Thomson, N C, Holloway, J W, Lockett, G A, Howarth, P H, Niven, R, Simpson, A, Blakey, J D, Tobin, M D, Postma, D S, Hall, I P, Wain, L V, Nawijn, M C, Brightling, C E, Koppelman, G H & Sayers, I 2020, ' Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium ', JCI insight, vol. 5, no. 8, pp. 1-19 . https://doi.org/10.1172/jci.insight.132446Test
JCI Insight
JCI Insight, 5(8):132446. AMER SOC CLINICAL INVESTIGATION INC

مصطلحات موضوعية: HAY-FEVER, EXPRESSION, 0301 basic medicine, medicine.medical_specialty, Genotype, IL1RL1, Single-nucleotide polymorphism, Genome-wide association study, Locus (genetics), Respiratory Mucosa, VARIANTS, Biology, Polymorphism, Single Nucleotide, 03 medical and health sciences, 0302 clinical medicine, Molecular genetics, Genetics, medicine, Humans, Genetic Predisposition to Disease, Genetic variation, GENOME-WIDE ASSOCIATION, Lung, Asthma, LARGE-SCALE, Haplotype, Cell Biology, General Medicine, ST2, medicine.disease, Interleukin-1 Receptor-Like 1 Protein, Phenotype, respiratory tract diseases, GENETIC RISK-FACTORS, DIFFERENTIATION, 030104 developmental biology, 030220 oncology & carcinogenesis, Immunology, IL-33, INTERLEUKIN-1 RECEPTOR, Research Article

وصف الملف: application/pdf; text

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35eec0d3bd47361ef723e102569f7099Test
https://doi.org/10.1172/jci.insight.132446Test