المؤلفون: Magnus Althage, Luna Simona Pane, Frank Seeliger, Mikael Bjursell, Ralph Knöll, Daniel Lindén, Katja Madeyski-Bengtson, Marta Perez-Alcazar, Roberto Nitsch, Mohammad Bohlooly-Y, Ryan Hicks, Alba Carreras, Marcello Maresca, Rosie Perkins, Jan Borén, Amir Taheri-Ghahfarokhi, Lorenz M. Mayr, Elke Ericson, Michelle J. Porritt, Pinar Akcakaya

المصدر: BMC Biology, Vol 17, Iss 1, Pp 1-14 (2019)
BMC Biology

مصطلحات موضوعية: Physiology, Hypercholesterolemia, Mice, Transgenic, Plant Science, Biology, Genome, General Biochemistry, Genetics and Molecular Biology, PCSK9, Base editing, 03 medical and health sciences, Mice, 0302 clinical medicine, Genome editing, Structural Biology, Gene knockin, Animals, Humans, Guide RNA, lcsh:QH301-705.5, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Gene Editing, 0303 health sciences, Cell Biology, Proprotein convertase, Cell biology, Evolocumab, Disease Models, Animal, Cholesterol, Liver, lcsh:Biology (General), Humanized mouse, Proprotein Convertase 9, CRISPR-Cas9, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery, Developmental Biology, Biotechnology, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66078274e7f09cb641aa7f88b07be760Test
http://link.springer.com/article/10.1186/s12915-018-0624-2Test

المؤلفون: Corey Nislow, Marinella Gebbia, Elke Ericson, Lawrence E. Heisler, Mike Tyers, Guri Giaever, Jan Wildenhain

المصدر: Ericson, E, Gebbia, M, Heisler, L E, Wildenhain, J, Tyers, M, Giaever, G & Nislow, C 2008, ' Off-Target Effects of Psychoactive Drugs Revealed by Genome-Wide Assays in Yeast ', PLoS Genetics, vol. 4, no. 8, e1000151, pp.-. https://doi.org/10.1371/journal.pgen.1000151Test
PLoS Genetics
PLoS Genetics, Vol 4, Iss 8, p e1000151 (2008)

مصطلحات موضوعية: Cancer Research, ved/biology.organism_classification_rank.species, Drug Evaluation, Preclinical, Drug Resistance, Pharmacology, 0302 clinical medicine, Genetics(clinical), Genetics (clinical), Clozapine, Oligonucleotide Array Sequence Analysis, media_common, 0303 health sciences, Genetics and Genomics/Functional Genomics, Cell Polarity, Telomere, 3. Good health, Chromatin, Genetics and Genomics/Gene Function, Protein Transport, Genome, Fungal, Research Article, medicine.drug, Drug, Saccharomyces cerevisiae Proteins, lcsh:QH426-470, media_common.quotation_subject, Saccharomyces cerevisiae, Biology, 03 medical and health sciences, medicine, Genetics, Humans, Genetics and Genomics/Genomics, Model organism, Gene, Molecular Biology, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Psychotropic Drugs, ved/biology, Gene Expression Profiling, Genetics and Genomics, Lipid Metabolism, biology.organism_classification, Yeast, Gene expression profiling, lcsh:Genetics, Protein Biosynthesis, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a653750956767887e47698b99d69260fTest
https://www.pure.ed.ac.uk/ws/files/8116364/PLOS_2008_Tyers_M.pdfTest

المؤلفون: Mohammed Bellaoui, Guri Giaever, Lisa Yu, Elke Ericson, Andres Lopez, Abdellah Hamal, Lawrence E. Heisler, Brahim El Bali, Corey Nislow, Charles Boone, Grant W. Brown, Angus McQuibban, Abderrahmane Anaflous

المصدر: PLoS Genetics, Vol 4, Iss 11, p e1000284 (2008)
PLoS Genetics

مصطلحات موضوعية: Cancer Research, Antifungal Agents, DNA Repair, lcsh:QH426-470, Pyridines, DNA damage, DNA repair, Saccharomyces cerevisiae, Genetics and Genomics/Pharmacogenomics, 01 natural sciences, 03 medical and health sciences, Chemical Biology, Genetics, medicine, Humans, Molecular Biology, Cells, Cultured, Genetics (clinical), Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, biology, 010405 organic chemistry, Genetics and Genomics/Functional Genomics, Mutagenesis, biology.organism_classification, Yeast, Mitochondria, 0104 chemical sciences, Nuclear DNA, lcsh:Genetics, Pyrimidines, Mechanism of action, Biochemistry, medicine.symptom, DNA Damage, Signal Transduction, Research Article, Nucleotide excision repair

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f6e3c747665c48072cc124af4222c0Test
https://doi.org/10.1371/journal.pgen.1000284Test