التفاصيل البيبلوغرافية
| العنوان: |
Genetic diversity of methicillin-resistant Staphylococcus aureus in a tertiary hospital in The Netherlands between 2002 and 2006. |
| المؤلفون: |
Nulens, E., Stobberingh, E. E., Smeets, E., van Dessel, H., Welling, M. A., Sebastian, S., van Tiel, F. H., Beisser, P. S., Deurenberg, R. H. |
| المصدر: |
European Journal of Clinical Microbiology & Infectious Diseases; Jun2009, Vol. 28 Issue 6, p631-639, 9p, 2 Charts, 2 Graphs |
| مصطلحات موضوعية: |
GENETICS, STAPHYLOCOCCUS aureus, STAPHYLOCOCCUS aureus infections, METHICILLIN resistance, PREVENTION of infectious disease transmission, RESEARCH, MEDICAL sciences, HOSPITALS |
| مصطلحات جغرافية: |
NETHERLANDS |
| مستخلص: |
The aim of this study was to investigate the methicillin-resistant Staphylococcus aureus (MRSA) clones isolated in a Dutch university hospital, situated near the borders of Belgium and Germany, between 2002 and 2006. MRSA strains ( n = 175) were characterized using spa and SCC mec typing. The presence of Panton Valentine leukocidin (PVL) was determined. Between 2002 and 2005, ST5-MRSA-IV was predominant, and the spa type of ST5-MRSA-IV changed from t002 to t447. ST5-MRSA-I, ST5-MRSA-II, ST228-MRSA-I, and ST247-MRSA-I were also observed in this period. From 2004, the MRSA genetic background became more diverse, and in 2006, ST5-MRSA-IV was only sporadically observed. From 2005, ST5-MRSA-II, ST8-MRSA-IV, ST22-MRSA-IV, and ST45-MRSA-IV were increasingly observed. Several other MRSA clones, such as ST239-MRSA-III, were found sporadically. Four PVL-positive MRSA isolates were observed, associated with ST80-MRSA-IV and ST8-MRSA-IV. ST5-MRSA-I, ST5-MRSA-II, ST5-MRSA-IV, and ST228-MRSA-I have not been described previously in The Netherlands. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
