نتائج البحث - "Steroidogenic factor 1"

1

The Orphan Nuclear Receptors Steroidogenic Factor-1 and Liver Receptor Homolog-1: Structure, Regulation, and Essential Roles in Mammalian Reproduction

المؤلفون: Marie-Charlotte Meinsohn, Kalyne Bertolin, Olivia Eilers Smith, Bruce D. Murphy

المصدر: Physiological Reviews. 99:1249-1279

مصطلحات موضوعية: Male, 0301 basic medicine, Steroidogenic factor 1, endocrine system, Protein Conformation, Physiology, Endometriosis, Receptors, Cytoplasmic and Nuclear, Breast Neoplasms, Biology, Ligands, Steroidogenic Factor 1, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Testicular Neoplasms, Pregnancy, Physiology (medical), Animals, Humans, Receptor, Molecular Biology, Transcription factor, Ovarian Neoplasms, Regulation of gene expression, Reproduction, Liver receptor homolog-1, General Medicine, Cell biology, 030104 developmental biology, Gene Expression Regulation, Nuclear receptor, 030220 oncology & carcinogenesis, Female, Signal transduction, Leydig Cell Tumor, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618135015cc960f4266d35ab18f48deeTest
https://doi.org/10.1152/physrev.00019.2018Test

2

Mutant NR5A1/SF-1 in patients with disorders of sex development shows defective activation of theSOX9TESCO enhancer

المؤلفون: Anthony Daniel Bird, Andrew H. Sinclair, Vincent R. Harley, Brittany Croft, Faustine Declosmenil, Peter Koopman, Louisa Mabel Ludbrook, Francis Poulat, Ken McElreavey, Kevin Christopher Knower, Brett Daniel Fisher, Janelle Ryan, Anu Bashamboo, Rajini Sreenivasan

المساهمون: University of Melbourne, Monash University [Victoria, Australia], Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Hudson Institute of Medical Research [Clayton], Génétique du Développement humain - Human developmental genetics, Institut Pasteur [Paris] (IP), Murdoch Children’s Research Institute [Melbourne, Australia], Institute for Molecular Bioscience, University of Queensland [Brisbane], This work was supported by the National Health and Medical Research Council of Australia (NHMRC) Program Grants 334314 and 546517 to V.H., P.K., and A.S. and by the Victorian Government's Operational Infrastructure Support Program (OIS). R.S. was supported by an Australian Postgraduate Award. B.C. is supported by an Australian Government Research Training Program Scholarship, through Monash University. V.H., P.K.. and A.S. are supported by NHMRC Research Fellowships.

المصدر: Human Mutation
Human Mutation, 2018, 39 (12), pp.1861-1874. ⟨10.1002/humu.23603⟩

مصطلحات موضوعية: Male, 0301 basic medicine, Steroidogenic factor 1, MESH: Sequence Analysis, DNA, testis-specific enhancer of SOX9, Mutant, sex determination, DSD, Ligands, Steroidogenic Factor 1, medicine.disease_cause, 0302 clinical medicine, MESH: Child, MESH: Ligands, Disorders of sex development, Child, Genetics (clinical), Regulation of gene expression, Genetics, Mutation, MESH: Infant, Newborn, MESH: Disorder of Sex Development, 46,XY, SOX9 Transcription Factor, MESH: Infant, MESH: Gene Expression Regulation, Enhancer Elements, Genetic, Testis determining factor, MESH: HEK293 Cells, Child, Preschool, SF-1, SOX9, Protein Binding, Adult, MESH: Mutation, Adolescent, 030209 endocrinology & metabolism, Biology, MESH: SOX9 Transcription Factor, 03 medical and health sciences, MESH: Computer Simulation, medicine, MESH: Protein Binding, Humans, Computer Simulation, Enhancer, MESH: Adolescent, MESH: Humans, Disorder of Sex Development, 46,XY, MESH: Child, Preschool, Infant, Newborn, Infant, MESH: Adult, [SDV.BDLR]Life Sciences [q-bio]/Reproductive Biology, Sequence Analysis, DNA, MESH: Steroidogenic Factor 1, medicine.disease, MESH: Male, HEK293 Cells, 030104 developmental biology, Gene Expression Regulation, MESH: Enhancer Elements, Genetic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bf3bb6c1222048f9bebd0d6dd26b0bTest
https://doi.org/10.1002/humu.23603Test

3

EHD3 positively regulated by NR5A1 participates in testosterone synthesis via endocytosis

المؤلفون: Fangxi Zhang, Lijun Ding, Guijun Yan, Fei Yu, Hongjie Pan, Yifan Li, Lingling Zhang, Runsheng Li, Yanhong Xu, Xiaofeng Wan

المصدر: Life sciences. 278

مصطلحات موضوعية: 0301 basic medicine, Male, endocrine system, Chromatin Immunoprecipitation, Endocytosis, Exosomes, Steroidogenic Factor 1, 030226 pharmacology & pharmacy, Clathrin, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mice, 0302 clinical medicine, Animals, Testosterone, General Pharmacology, Toxicology and Pharmaceutics, RNA, Small Interfering, Promoter Regions, Genetic, Regulation of gene expression, Mice, Knockout, Gene knockdown, biology, Chemistry, Gene targeting, Leydig Cells, General Medicine, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Gene Expression Regulation, Knockout mouse, biology.protein, Female, CRISPR-Cas Systems, Carrier Proteins, Chromatin immunoprecipitation, Plasmids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d1b6935a684bde974441f12ab56f40Test
https://pubmed.ncbi.nlm.nih.gov/33964295Test

4

CRISPR/dCas9‐mediated activation of multiple endogenous target genes directly converts human foreskin fibroblasts into Leydig‐like cells

المؤلفون: Zhiyuan Zhang, Hua Huang, Xiaoyu Xing, Xiangyu Zou, Liang Zhong, Jin Zhou, Yanping Hou, Jie Sun

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: 0301 basic medicine, Male, Transcriptional Activation, endocrine system, gene activation, Foreskin, Endogeny, Biology, Steroidogenic Factor 1, Chorionic Gonadotropin, Human chorionic gonadotropin, Cell Line, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Testosterone, Regulation of gene expression, Leydig cell, induced Leydig cells, male hypogonadism, reprogramming, Leydig Cells, Cell Biology, Original Articles, Fibroblasts, Cellular Reprogramming, Cell biology, GATA4 Transcription Factor, Transplantation, 030104 developmental biology, medicine.anatomical_structure, Cell culture, 030220 oncology & carcinogenesis, human foreskin fibroblasts, Molecular Medicine, Original Article, CRISPR-Cas Systems, Reprogramming, CRISPR‐Cas9, RNA, Guide, Kinetoplastida, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2c24b032005e1efa1e815559c9e70bTest
http://europepmc.org/articles/PMC6714237Test

5

New evidences on the regulation of SF-1 expression by POD1/TCF21 in adrenocortical tumor cells

المؤلفون: Monica M. França, Antonio M. Lerario, Maria Candida Barisson Villares Fragoso, Claudimara Ferini Pacicco Lotfi

المصدر: Clinics
Clinics, Vol 72, Iss 6, Pp 391-394
Clinics; v. 72 n. 6 (2017); 391-394
Clinics; Vol. 72 Núm. 6 (2017); 391-394
Clinics; Vol. 72 No. 6 (2017); 391-394
Universidade de São Paulo (USP)
instacron:USP
Clinics, Volume: 72, Issue: 6, Pages: 391-394, Published: JUN 2017

مصطلحات موضوعية: Steroidogenic factor 1, Small interfering RNA, POD1, Blotting, Western, Immunoblotting, Down-Regulation, Biology, Real-Time Polymerase Chain Reaction, Steroidogenic Factor 1, siRNA-POD1, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Gene expression, Basic Helix-Loop-Helix Transcription Factors, medicine, Humans, Adrenocortical carcinoma, Gene silencing, Transcription factor, TCF21, Regulation of gene expression, lcsh:R5-920, Gene knockdown, Adrenocortical Tumor Cells, General Medicine, medicine.disease, Adrenal Cortex Neoplasms, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Cancer research, SF-1, lcsh:Medicine (General), Rapid Communication, 030215 immunology