دورية أكاديمية
孤立性肺结节的危险因素 ; Solitary pulmonary nodules: a risk factor analysis
| العنوان: | 孤立性肺结节的危险因素 ; Solitary pulmonary nodules: a risk factor analysis |
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| المؤلفون: | 李运, 隋锡朝, 杨德松, 刘彦国, 李剑锋, 杨帆, 姜冠潮, 刘军, 王俊 |
| المساهمون: | 北京大学人民医院胸外科,100044 |
| المصدر: | 万方 ; http://d.g.wanfangdata.com.cn/Periodical_zhxxxgwk201003006.aspxTest |
| بيانات النشر: | 中华胸心血管外科杂志 |
| سنة النشر: | 2010 |
| المجموعة: | Peking University Institutional Repository (PKU IR) / 北京大学机构知识库 |
| مصطلحات موضوعية: | 硬币病变,肺, 危险因素, 回归分析, Coin lesion,pulmonary, Risk factors, Regression analysis |
| الوصف: | 目的 通过临床资料与孤立性肺结节(SPN)相关的单因素和多因素分析,评估其对SPN良、恶性判断的影响.方法 2000年1月至2009年7月经手术切除明确病理诊断的孤立性肺结节病人390例,其中男212例,女178例.年龄17～86岁,平均(57.1±14.8)岁.结节最大径0.2～3.0 cm,平均(2.02±0.78)cm.分别收集以下资料(1)年龄、性别、病程、症状、吸烟史及吸烟量、既往肿瘤史、肿瘤家族史;(2)影像学检查资料:肿瘤部位、肿瘤最大径、有无钙化、毛刺、分叶、胸膜牵拉征、界限清楚、血管集束征、纵隔淋巴结肿大;(3)术中探查结果:与胸壁有无粘连、有无胸膜皱缩征、有无胸腔积液.结果 肿瘤剜除术20例,楔形切除153例,肺叶切除217例.术后病理为良性病变130例,其中结核瘤49例,错构瘤33例,炎性假瘤27例,硬化性血管瘤9例,霉菌球3例,肺囊肿2例,淋巴组织增生2例,支气管扩张2例,动静脉瘘1例,间质性肺炎1例,神经纤维瘤1例;恶性病变260例,其中腺癌164例,鳞癌40例,肺泡细胞癌23例,肺转移癌20例,小细胞癌9例,类癌4例.单因素及逻辑回归分析显示,病人年龄、肿瘤最大径、伴有钙化、边界清楚及胸膜皱缩在良、恶性病变中的数据差异有统计学意义.而病人性别、吸烟史及吸烟量、术前有无症状、影像学检查有无分叶、毛刺、胸膜牵拉征、纵隔淋巴结肿大及术中探查有无胸腔积液在良、恶性肿瘤病人中的数据差异无统计学意义.结论 病人年龄、肿瘤最大径、伴有钙化及胸膜皱缩,对判断肺结节的良、恶性有显著意义. ; 0bjective Evaluate the clinical factors affecting the definite pathological diagnosis of solitary pulmonary odules(SPN).Methods From Jan 2000 to July 2009,390 patients(212 men,178 women,median age 57.1 years,range from 17 to 86 years)got definite pathological diagnosis of solitary pulmonary nodules in our Institute were investigated.All following clinical data were collected:age,gender,course of disease,symptoms,history and quantity of smoking,history of tumor,family history of tumor,site,diameter,calcification,spicular sign,border,lobulated,traction of pleural,vascular convergence sign,lymph nodes of mediastinum,adhesion,depression of pleural,pleural effusion.Results The surgical procedures included 20 tumor enucleation,153 wedge resection,and 217 lobectomy.There were 130 benign lesions,including hamartoma(n=33),arteriovenous istula(n=1),cyst(n=2),interstitial pneumonia(n=1),tuberculoma(n=49),lymphoproliferative(n=2),fungal ball(n=3),neurofibroma(n=1),inflammatory pseudotumor(n=27),sclerosing hemangioma(n=9),bronchiectasis(n=2).260 were malignant lesions,including Alveolar cell carcinoma(n=23),Metastatic carcinoma(n=20),Carcinoid(n=4),Squamous cell carcinoma(n=40),adenecarcinoma(n=164),Small cell carcinoma(n=9).Single factor analysis and Logistic regression analysis show that there were significant differences in age, diameter,border,calcification and depression ... |
| نوع الوثيقة: | journal/newspaper |
| اللغة: | Chinese |
| تدمد: | 1001-4497 |
| العلاقة: | 中华胸心血管外科杂志.2010,26,(3),161-164.; 1255545; http://hdl.handle.net/20.500.11897/135693Test |
| DOI: | 10.3760/cma.j.issn.1001-4497.2010.03.008 |
| الإتاحة: | https://doi.org/20.500.11897/135693Test https://doi.org/10.3760/cma.j.issn.1001-4497.2010.03.008Test https://hdl.handle.net/20.500.11897/135693Test |
| رقم الانضمام: | edsbas.8084CDFB |
| قاعدة البيانات: | BASE |
| تدمد: | 10014497 |
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| DOI: | 10.3760/cma.j.issn.1001-4497.2010.03.008 |