دورية أكاديمية
The added value of the visual analysis of DWI in post-surgery follow-up of soft tissue sarcoma of the extremities: do we really need ADC?
| العنوان: | The added value of the visual analysis of DWI in post-surgery follow-up of soft tissue sarcoma of the extremities: do we really need ADC? |
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| المؤلفون: | Zampa, Virna, Aringhieri, Giacomo, Tintori, Rachele, Rossi, Piercarlo, Andreani, Lorenzo, Franchi, Alessandro |
| المساهمون: | Zampa, Virna, Aringhieri, Giacomo, Tintori, Rachele, Rossi, Piercarlo, Andreani, Lorenzo, Franchi, Alessandro |
| سنة النشر: | 2023 |
| المجموعة: | ARPI - Archivio della Ricerca dell'Università di Pisa |
| مصطلحات موضوعية: | ADC, DWI, MRI, Post-surgery, Recurrence, Soft tissue sarcoma |
| الوصف: | IntroductionMRI has a fundamental role in the follow-up of soft tissue sarcomas (STSs). However, the differentiation of recurrences/residual disease from post-surgical changes is a complex task, with a central role for the radiologist.Materials and methodsWe retrospectively evaluated 64 post-surgery MRI for extremities STSs. MR protocol included DWI (b = 0, 1000). Two radiologists were asked to consensually evaluate: presence/absence of tumoral nodules, lesion conspicuity, imaging diagnostic confidence, ADC values, and DWI overall image quality. The gold standard was histology or MR follow-up.ResultsThirty-seven lesions in 29/64 patients were confirmed as local recurrence or residual disease (n = 16 <= 1 cm) with 1 MR false positive. On DWI, the conspicuity of the proved tumor lesions resulted excellent in 29/37, good in 3/37 and low in 5/37, higher than conventional imaging. A statistically significant higher diagnostic confidence of DWI compared to conventional imaging (p < 0.001) and DCE (p = 0.009) was observed. In the 37 histologically confirmed lesions, mean ADC value was 1.31 x 10(-9) m(2)/s. Overall scar tissues mean ADC was 1.70 x 10(-9) m(2)/s. DWI quality resulted adequate in 81% and unsatisfactory in 5%.ConclusionsIn this highly heterogeneous group of tumors, the role of ADC seems to be limited. Based on our experience, looking at DWI images makes the lesions promptly and easily detectable. This technique gives less deceptive findings making the reader more confident in detecting/excluding tumoral tissue; the main drawback is the image quality and the lack of standardization. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/36995546; info:eu-repo/semantics/altIdentifier/wos/WOS:000960840600001; volume:128; issue:4; firstpage:467; lastpage:479; numberofpages:13; journal:LA RADIOLOGIA MEDICA; https://hdl.handle.net/11568/1182147Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85151426701 |
| DOI: | 10.1007/s11547-023-01613-w |
| الإتاحة: | https://doi.org/10.1007/s11547-023-01613-wTest https://hdl.handle.net/11568/1182147Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.95B95CF7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s11547-023-01613-w |
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