نتائج البحث - "Manuel Portero-Otin"

1

Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway

المؤلفون: Marta Llovera, Marisol Ruiz-Meana, Andrea Irazoki, Carlos Lana, Javier Inserte, Manuel Portero-Otin, Juan G. Valero, Aida Beà, Guillermo López-Lluch, Antonio Zorzano, Daniel Sanchis, Patricia Pérez-Galán

المساهمون: Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), Fundació La Marató de TV3, Diputació de Lleida, Generalitat de Catalunya, Instituto de Salud Carlos III, Centres de Recerca de Catalunya, Institut Català de la Salut, [Beà A, Lana C] Cell Signaling & Apoptosis Group, Institut de Recerca Biomedica de Lleida (IRBLleida), Universitat de Lleida, Spain. [Valero JG] Department of Hematology-Oncology, Institut d’Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. Centro de Investigacion Biomédica en Red-Oncología (CIBERONC), Barcelona, Spain. [Irazoki A] Departament de Bioquímica i Biomedicina Molecular, Facultat de Biologia, Institute for Research in Biomedicine (IRB Barcelona), Barcelona Institute of Science and Technology (BIST), Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Universitat de Barcelona, Spain. [López-Lluch G] Andalusian Center of Developmental Biology, Pablo de Olavide University, Sevilla, Spain. Centro de Investigación Biomédica en Red Enfermedades Raras (CIBERER), Sevilla, Spain. [Portero-Otín M] Department of Experimental Medicine, IRBLleida, University of Lleida, Lleida, Spain. [Inserte J, Ruiz-Meana M] Laboratori de Cardiologia Experimental, Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institut de Recerca (VHIR), Barcelona, Spain. Universitat Autònoma de Barcelona, Spain. Centro de Investigación Biomédica en Red-CV (CIBER-CV), Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus

المصدر: Repositorio Abierto de la UdL
Universitad de Lleida
Scientia
Digital.CSIC. Repositorio Institucional del CSIC
instname

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce5e080d6d003f7c54330a05dbb0cacdTest
http://hdl.handle.net/10459.1/72607Test

2

المؤلفون: Manuel Portero-Otin, Reinald Pamplona, Èlia Obis, Joaquim Sol, José Daniel Galo-Licona, Victoria Ayala, Meritxell Martín-Gari, Paula Ramos, Mariona Jové, Pascual Torres, Rosanna Cabré, Natalia Mota-Martorell, Iván Canales, Lara Nogueras, Isidro Ferrer

المصدر: Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 22, Iss 12517, p 12517 (2021)
Repositorio Abierto de la UdL
Universitad de Lleida
International Journal of Molecular Sciences
Volume 22
Issue 22

مصطلحات موضوعية: Aging, Cerebellum, (lip)oxidation-derived protein damage markers, chemistry.chemical_compound, Methionine, Biology (General), Spectroscopy, mass spectrometry, glycerophospholipids, chemistry.chemical_classification, Chromatography, medicine.diagnostic_test, Chemistry, Brain, General Medicine, (Lip)oxidation-derived protein damage markers, Lipidome, Lipids, Frontal Lobe, Computer Science Applications, medicine.anatomical_structure, medicine.medical_specialty, QH301-705.5, Glycerophospholipids, Article, Catalysis, Inorganic Chemistry, Envelliment, Internal medicine, medicine, Animals, Humans, Physical and Theoretical Chemistry, QD1-999, Molecular Biology, Phosphatidylethanolamine, Sphingolipids, sphingolipids, methionine restriction, Mass spectrometry, Cholesterol, aging, Organic Chemistry, glycerolipids, Glycerolipids, Fatty acid, Sphingolipid, Rats, Sterol lipids, Oxidative Stress, Endocrinology, sterol lipids, Lípids, Lipidomics, Reactive Oxygen Species, Lipid profile, Methionine restriction, Esfingolípids

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d4363a02e395affadc7f32004ee5e4Test
https://doi.org/10.3390/ijms222212517Test

3

Aberrant regulation of the GSK‐3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy

المؤلفون: Noel Y. Calingasan, Nathalie Launay, M. Flint Beal, Aurora Pujol, Magali Dumont, Isidre Ferrer, Reinald Pamplona, Alba Naudí, Stéphane Fourcade, Manuel Portero-Otin, Montserrat Ruiz, Pablo Ranea-Robles

المساهمون: Institut d'Investigació Biomèdica de Bellvitge [Barcelone] (IDIBELL), CIBER de Enfermedades Raras (CIBERER), Weill Medical College of Cornell University [New York], Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Universitat de Lleida, University of Barcelona, Centro de Investigacion Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III [Madrid] (ISC), Institució Catalana de Recerca i Estudis Avançats (ICREA), Universitat de Barcelona

المصدر: EMBO Molecular Medicine
EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (8), pp.e8604. ⟨10.15252/emmm.201708604⟩
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
EMBO Molecular Medicine, Vol 10, Iss 8, Pp n/a-n/a (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Medicine (General), [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Anti-Inflammatory Agents, QH426-470, medicine.disease_cause, ATP Binding Cassette Transporter, Subfamily D, Member 1, Antioxidants, chemistry.chemical_compound, Mice, 0302 clinical medicine, GSK-3, Ús terapèutic, oxidative stress, GSK‐3, Gliosis, Adrenoleukodystrophy, Research Articles, chemistry.chemical_classification, Mice, Knockout, Organelle Biogenesis, dimethyl fumarate, Dimethyl fumarate, adrenoleukodystrophy, Chemistry, Peroxisome, Metabolisme, 3. Good health, Cell biology, Molecular Medicine, medicine.symptom, Glycogen, Research Article, NF-E2-Related Factor 2, Inflammation, Mitochondrial depletion, NRF2, 03 medical and health sciences, R5-920, Genetics, medicine, Animals, Humans, Reactive oxygen species, Glycogen Synthase Kinase 3 beta, Therapeutic use, medicine.disease, Glicogen, Disease Models, Animal, 030104 developmental biology, Metabolism, Genetics, Gene Therapy & Genetic Disease, Reactive Oxygen Species, Proto-Oncogene Proteins c-akt, 030217 neurology & neurosurgery, Oxidative stress, Neuroscience

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19ee868f25ccca7d0b4720a14673620Test
https://hal.sorbonne-universite.fr/hal-02120916Test

4

Specific Lipidome Signatures in Central Nervous System from Methionine-Restricted Mice

المؤلفون: Rosanna Cabré, Manuel Portero-Otin, Reinald Pamplona, Omar Ramírez-Núñez, Corinne M. Spickett, Alba Naudí, Victoria Ayala, Mariona Jové

المصدر: Journal of Proteome Research. 12:2679-2689

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d6caae770ca787059202f104833562Test
https://doi.org/10.1021/pr400064aTest

5

Oxidative stress underlying axonal degeneration in adrenoleukodystrophy: A paradigm for multifactorial neurodegenerative diseases?

المؤلفون: Aurora Pujol, Elena Galea, Reinald Pamplona, Nathalie Launay, Montserrat Ruiz, Manuel Portero-Otin, Patrick Aubourg, Isidre Ferrer

المصدر: Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease; Vol 1822
Recercat. Dipósit de la Recerca de Catalunya
instname
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2876319969381899134ef6696dd884ceTest

6

Stanozolol treatment decreases the mitochondrial ROS generation and oxidative stress induced by acute exercise in rat skeletal muscle

المؤلفون: Reinald Pamplona, Ana Saborido, A Megías, Alba Naudí, Manuel Portero-Otin

المصدر: Journal of Applied Physiology. 110:661-669

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100d60a1fcaed996776cefe006f0bb62Test
https://doi.org/10.1152/japplphysiol.00790.2010Test

7

The β-Blocker Atenolol Lowers the Longevity-Related Degree of Fatty Acid Unsaturation, Decreases Protein Oxidative Damage, and Increases Extracellular Signal-Regulated Kinase Signaling in the Heart of C57BL/6 Mice

المؤلفون: Gustavo Barja, Reinald Pamplona, Ines Sanchez-Roman, Victoria Ayala, Alba Naudí, José Ignacio Gómez, Manuel Portero-Otin, Mónica López-Torres

المصدر: Rejuvenation Research. 13:683-693

مصطلحات موضوعية: Aging, medicine.medical_specialty, Glycosylation, MAP Kinase Signaling System, Longevity, Oxidative phosphorylation, Biology, Mitochondrion, medicine.disease_cause, Protein oxidation, Mitochondria, Heart, Electron Transport, Lipid peroxidation, Membrane Lipids, Mice, chemistry.chemical_compound, Oxygen Consumption, Internal medicine, medicine, Animals, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Heart metabolism, chemistry.chemical_classification, Myocardium, Fatty acid, Atenolol, Adrenergic beta-1 Receptor Antagonists, Mice, Inbred C57BL, Oxidative Stress, Endocrinology, chemistry, Fatty Acids, Unsaturated, Geriatrics and Gerontology, Reactive Oxygen Species, Oxidation-Reduction, Biomarkers, Oxidative stress, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ab73837c30ec1553952a53b833d813Test
https://doi.org/10.1089/rej.2010.1062Test

8

Expression of the yeast NADH dehydrogenase Ndi1 in Drosophila confers increased lifespan independently of dietary restriction

المصدر: Proceedings of the National Academy of Sciences. 107:9105-9110

مصطلحات موضوعية: Aging, Saccharomyces cerevisiae Proteins, Blotting, Western, Longevity, Respiratory chain, Oxidative phosphorylation, Mitochondrion, medicine.disease_cause, NADH dehydrogenase activity, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Caloric Restriction, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Electron Transport Complex I, Multidisciplinary, biology, Histocytochemistry, Reverse Transcriptase Polymerase Chain Reaction, NADH dehydrogenase, Biological Sciences, Mitochondria, Oxidative Stress, Drosophila melanogaster, Biochemistry, Sirtuin, biology.protein, RNA Interference, Reactive Oxygen Species, 030217 neurology & neurosurgery, Oxidative stress

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b6b82970c8765c60f5900d4c5235228Test
https://doi.org/10.1073/pnas.0911539107Test

9

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy

المؤلفون: Ronald J.A. Wanders, Stephan Kemp, Eric Hahnen, Reinald Pamplona, Aurora Pujol, Manuel Portero-Otin, Jean-Louis Mandel, Montserrat Ruiz, Cristina Guilera, Stéphane Fourcade, Patrick Aubourg, Alba Naudí, Brunhilde Wirth, Nathalie Cartier, Lars Brichta, Georges Dacremont

المساهمون: Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases, Paediatric Metabolic Diseases

المصدر: Human Molecular Genetics; Vol 19
Human molecular genetics, 19(10), 2005-2014. Oxford University Press
Recercat. Dipósit de la Recerca de Catalunya
instname

مصطلحات موضوعية: endocrine system diseases, Antioxidants, Mice, 0302 clinical medicine, Adrenoleukodystrophy, Child, Genetics (clinical), 0303 health sciences, Valproic Acid, biology, Fatty Acids, Histone deacetylase inhibitor, General Medicine, Peroxisome, 3. Good health, Spinal Cord, lipids (amino acids, peptides, and proteins), medicine.drug, congenital, hereditary, and neonatal diseases and abnormalities, endocrine system, medicine.medical_specialty, Adolescent, Fatty Acid Elongases, medicine.drug_class, Oxidative phosphorylation, ATP Binding Cassette Transporter, Subfamily D, 03 medical and health sciences, Acetyltransferases, Internal medicine, Genetics, medicine, ABCD2, Animals, Humans, Rats, Wistar, Molecular Biology, 030304 developmental biology, Leukodystrophy, nutritional and metabolic diseases, Metabolism, Fibroblasts, medicine.disease, Rats, Histone Deacetylase Inhibitors, Oxidative Stress, Endocrinology, Gene Expression Regulation, Leukocytes, Mononuclear, biology.protein, ATP-Binding Cassette Transporters, Reactive Oxygen Species, Biomarkers, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b803642da36ac0f226c05ca9b6362c84Test
https://doi.org/10.1093/hmg/ddq082Test

10

Effect of methionine dietary supplementation on mitochondrial oxygen radical generation and oxidative DNA damage in rat liver and heart

المؤلفون: Gustavo Barja, José Gómez, Reinald Pamplona, Pilar Caro, Inés Sánchez, Alba Naudí, Mónica López-Torres, Mariona Jové, Manuel Portero-Otin

المصدر: Journal of Bioenergetics and Biomembranes. 41:309-321

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccbc8cbe66514bc76208e9d957356608Test
https://doi.org/10.1007/s10863-009-9229-3Test

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