دورية أكاديمية
From intestinal colonization to systemic infections: Candida albicans translocation and dissemination
| العنوان: | From intestinal colonization to systemic infections: Candida albicans translocation and dissemination |
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| المؤلفون: | Jakob L. Sprague, Lydia Kasper, Bernhard Hube |
| المصدر: | Gut Microbes, Vol 14, Iss 1 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | Candida albicans, intestinal translocation, dissemination, fungi, gut colonization, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | ABSTRACTCandida species are the most prevalent cause of invasive fungal infections, of which Candida albicans is the most common. Translocation across the epithelial barrier into the bloodstream by intestinal-colonizing C. albicans cells serves as the main source for systemic infections. Understanding the fungal mechanisms behind this process will give valuable insights on how to prevent such infections and keep C. albicans in the commensal state in patients with predisposing conditions. This review will focus on recent developments in characterizing fungal translocation mechanisms, compare what we know about enteric bacterial pathogens with C. albicans, and discuss the different proposed hypotheses for how C. albicans enters and disseminates through the bloodstream immediately following translocation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 19490976 1949-0984 1949-0976 |
| العلاقة: | https://doaj.org/toc/1949-0976Test; https://doaj.org/toc/1949-0984Test |
| DOI: | 10.1080/19490976.2022.2154548 |
| الوصول الحر: | https://doaj.org/article/9a3eda3b70b74f6bb80f094e0042d9a9Test |
| رقم الانضمام: | edsdoj.9a3eda3b70b74f6bb80f094e0042d9a9 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19490976 19490984 |
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| DOI: | 10.1080/19490976.2022.2154548 |