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Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker

التفاصيل البيبلوغرافية
العنوان: Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker
المؤلفون: Tess Cruickshank, Teresa M. MacDonald, Susan P. Walker, Emerson Keenan, Kirsten Dane, Anna Middleton, Valerie Kyritsis, Jenny Myers, Catherine Cluver, Roxanne Hastie, Lina Bergman, Damanpreet Garcha, Ping Cannon, Elizabeth Murray, Tuong‐Vi Nguyen, Richard Hiscock, Natasha Pritchard, Natalie J. Hannan, Stephen Tong, Tu’uhevaha J. Kaitu’u‐Lino
المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 16 (2021)
بيانات النشر: Wiley, 2021.
سنة النشر: 2021
المجموعة: LCC:Diseases of the circulatory (Cardiovascular) system
مصطلحات موضوعية: biomarker, placental growth factor, preeclampsia, pregnancy, Diseases of the circulatory (Cardiovascular) system, RC666-701
الوصف: Background We investigated the biomarker potential of growth differentiation factor 15 (GDF‐15), a stress response protein highly expressed in placenta, to predict preeclampsia. Methods and Results In 2 prospective cohorts (cohort 1: 960 controls, 39 women who developed preeclampsia; cohort 2: 950 controls, 41 developed preeclampsia), plasma concentrations of GDF‐15 at 36 weeks' gestation were significantly increased among those who developed preeclampsia (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2047-9980
العلاقة: https://doaj.org/toc/2047-9980Test
DOI: 10.1161/JAHA.120.020302
الوصول الحر: https://doaj.org/article/66a4629a4d3e44588e70e5f1551eddcfTest
رقم الانضمام: edsdoj.66a4629a4d3e44588e70e5f1551eddcf
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20479980
DOI:10.1161/JAHA.120.020302