دورية أكاديمية
أعرض في EDS

Patterns of lower risk myelodysplastic syndrome progression: factors predicting progression to high-risk myelodysplastic syndrome and acute myeloid leukemia

التفاصيل البيبلوغرافية
العنوان: Patterns of lower risk myelodysplastic syndrome progression: factors predicting progression to high-risk myelodysplastic syndrome and acute myeloid leukemia
المؤلفون: Akriti G. Jain, Somedeb Ball, Luis Aguirre, Najla Al Ali, David Kaldas, Sara Tinsley-Vance, Andrew Kuykendall, Onyee Chan, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami Komrokji
المصدر: Haematologica, Vol 999, Iss 1 (2024)
بيانات النشر: Ferrata Storti Foundation, 2024.
سنة النشر: 2024
المجموعة: LCC:Diseases of the blood and blood-forming organs
مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5
الوصف: The patterns of low risk myelodysplastic syndrome (MDS) progression, and the clinical and molecular features of those patterns are not well described. We divided our low risk (LR) MDS patients (n=1914) into 4 cohorts: 1) Patients who remained LR-MDS (LR-LR; n=1300; 68%), 2) Patients who progressed from LR to HR MDS (LR-HR) without AML transformation (n=317; 16.5%), 3) Patients who progressed from LR to HR MDS and then AML (LR-HR-AML; n=124; 6.5%), 4) Patients who progressed from LR MDS to AML directly (LR-AML; n=173; 9%). Risk factors for progression included male gender, low absolute neutrophil count (ANC), low platelet count, high bone marrow (BM) blasts, ferritin >1000 mcg/L, albumin
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0390-6078
1592-8721
العلاقة: https://haematologica.org/article/view/11425Test; https://doaj.org/toc/0390-6078Test; https://doaj.org/toc/1592-8721Test
DOI: 10.3324/haematol.2023.283661
الوصول الحر: https://doaj.org/article/8c6b1ac7b01a432c91e1cb0cd4fc8575Test
رقم الانضمام: edsdoj.8c6b1ac7b01a432c91e1cb0cd4fc8575
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:03906078
15928721
DOI:10.3324/haematol.2023.283661