دورية أكاديمية
COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review
| العنوان: | COVID-19 Neurological Manifestations and Underlying Mechanisms: A Scoping Review |
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| المؤلفون: | Angela Wenting, Angélique Gruters, Yindee van Os, Sonja Verstraeten, Susanne Valentijn, Rudolf Ponds, Marjolein de Vugt |
| المصدر: | Frontiers in Psychiatry, Vol 11 (2020) |
| بيانات النشر: | Frontiers Media S.A. |
| سنة النشر: | 2020 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Corona Virus Disease 2019, neurological, neurotropic, cognitive, scoping review, Psychiatry, RC435-571 |
| الوصف: | BackgroundIn the Corona Virus Disease 2019 (COVID-19) pandemic, the primary problem is respiratory-related, but there also is increasing evidence of central nervous system (CNS) involvement. This study aims to summarize the literature on neurological manifestations of COVID-19, underlying mechanisms of CNS involvement and cognitive consequences.MethodsA scoping review was conducted with multiple searches in PubMed, PsycInfo, and CINAHL databases. Full text articles in English were included if they involved humans with COVID-19. The search was updated twice, the latest on 19 May 2020.ResultsAfter screening 266 records and cross referencing, 85 articles were included. The articles were case studies, opinion papers, letters to editors, and a few observational studies. No articles were found regarding cognitive consequences in COVID-19 patients. All reported on neurological manifestations and/or underlying mechanisms of CNS involvement in COVID-19.ConclusionNeurological manifestations of COVID-19 vary from mild (e.g. loss of taste and smell, dizziness, headache) to severe (e.g. ischemic stroke, encephalitis). Underlying pathways are suggested to be both indirect (as a result of thrombotic complication, inflammatory consequences, hypoxia, blood pressure dysregulation), and direct (neurotropic properties of the virus). Since most articles were opinion papers and no studies have been conducted on cognitive consequences, further research is warranted. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1664-0640 |
| العلاقة: | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00860/fullTest; https://doaj.org/toc/1664-0640Test; https://doaj.org/article/ab4a76faa10b4a10a6331c71ed299a91Test |
| DOI: | 10.3389/fpsyt.2020.00860 |
| الإتاحة: | https://doi.org/10.3389/fpsyt.2020.00860Test https://doaj.org/article/ab4a76faa10b4a10a6331c71ed299a91Test |
| رقم الانضمام: | edsbas.880A92CD |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16640640 |
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| DOI: | 10.3389/fpsyt.2020.00860 |