يعرض 1 - 10 نتائج من 475 نتيجة بحث عن '"Pinacidil"', وقت الاستعلام: 1.68s تنقيح النتائج
  1. 1
    ROS-associated mechanism of different concentrations of pinacidil postconditioning in the rat cardiac Nrf2-ARE signaling pathway

    المؤلفون: Wei Chen, Mengyuan Deng, Ying Wang, Haiying Wang, Tian Yu, Wenjing Zhou

    المصدر: Molecular Medicine Reports

    مصطلحات موضوعية: Cardiac function curve, Male, Cancer Research, Antioxidant, P50, NF-E2-Related Factor 2, medicine.medical_treatment, ischemia-reperfusion injury, Myocardial Ischemia, Gene Expression, Myocardial Reperfusion Injury, Pharmacology, Protective Agents, Biochemistry, Antioxidants, Rats, Sprague-Dawley, chemistry.chemical_compound, Genetics, medicine, Animals, Myocytes, Cardiac, Molecular Biology, chemistry.chemical_classification, reactive oxygen species, Reactive oxygen species, Oncogene, Chemistry, Myocardium, Pinacidil, Articles, pinacidil nuclear factor E2-related factor-antioxidation reaction pathway, Mitochondria, Rats, Oncology, Apoptosis, Molecular Medicine, Signal transduction, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfe33b1202c4b18eac8fffafe42b5beTest
    http://europepmc.org/articles/PMC8060791Test


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  2. 2
    The Effect of Hemp (Cannabis sativa L.) Seeds and Hemp Seed Oil on Vascular Dysfunction in Obese Male Zucker Rats

    المؤلفون: Michał Majewski, Adam Jurgoński

    المصدر: Nutrients
    Nutrients, Vol 13, Iss 2575, p 2575 (2021)
    Nutrients; Volume 13; Issue 8; Pages: 2575

    مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Vasodilation, Blood Pressure, Antioxidants, chemistry.chemical_compound, thoracic aorta, Blood plasma, heart rate, TX341-641, Food science, pinacidil, Glucose tolerance test, Nutrition and Dietetics, medicine.diagnostic_test, Hemp oil, Blood Proteins, Malondialdehyde, Zucker rat, Lipids, Seeds, mean arterial pressure, U-46619, Zucker Rats, NS1619, thromboxane-A2, glucose tolerance test, Cannabis sativa, Article, Cardiovascular Physiological Phenomena, 03 medical and health sciences, Thromboxane A2, medicine, Animals, Obesity, Cannabis, 030109 nutrition & dietetics, Nutrition. Foods and food supply, Plant Extracts, Myocardium, Rats, Rats, Zucker, 030104 developmental biology, chemistry, Vasoconstriction, Dietary Supplements, Uric acid, Lipid Peroxidation, Food Science

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0725201f3bc2862765f731180606d571Test
    http://europepmc.org/articles/PMC8398088Test


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  3. 3
    KATP Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia

    المؤلفون: Wei Sun, Donglong Chen, Hong Li, Jiansu Chen, Jacey Hongjie Ma, Chang Luo, Shibo Tang, Heping Xu

    المصدر: Li, H, Chen, D, Sun, W, Chen, J, Luo, C, Xu, H, Ma, J H & Tang, S 2021, ' KATP Opener Attenuates Diabetic-Induced Müller Gliosis and Inflammation by Modulating Kir6.1 in Microglia ', Investigative ophthalmology & visual science, vol. 62, no. 2, 3 . https://doi.org/10.1167/iovs.62.2.3Test
    Investigative Ophthalmology & Visual Science

    مصطلحات موضوعية: 0301 basic medicine, Male, microglia, Inflammation, Proinflammatory cytokine, Diabetes Mellitus, Experimental, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Western blot, KATP Channels, SDG 3 - Good Health and Well-being, Membrane Transport Modulators, medicine, Animals, Gliosis, Cells, Cultured, Microglia, medicine.diagnostic_test, Glial fibrillary acidic protein, biology, Chemistry, Müller cell, Pinacidil, DNA, Immunohistochemistry, Cell biology, Rats, diabetic retinopathy, 030104 developmental biology, medicine.anatomical_structure, Retinal Cell Biology, Gene Expression Regulation, biology.protein, cardiovascular system, Tumor necrosis factor alpha, sense organs, medicine.symptom, 030217 neurology & neurosurgery, potassium channel

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b7e8ee94048c476c1da6d3d58c428aTest
    https://pure.qub.ac.uk/en/publications/9e0e655e-5e22-461a-84d2-a51d21fed4ecTest


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  4. 4
    The toxic effects of monosodium glutamate (MSG) – The involvement of nitric oxide, prostanoids and potassium channels in the reactivity of thoracic arteries in MSG-obese rats

    المؤلفون: Michał Majewski, Jerzy Juśkiewicz, Bartosz Fotschki, Adam Jurgoński

    المصدر: Toxicology and Applied Pharmacology. 359:62-69

    مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Potassium Channels, Monosodium glutamate, Down-Regulation, Aorta, Thoracic, 030204 cardiovascular system & hematology, Nitric Oxide, Toxicology, Muscle, Smooth, Vascular, Nitric oxide, Thromboxane A2, 03 medical and health sciences, chemistry.chemical_compound, Thoracic Arteries, 0302 clinical medicine, Internal medicine, Sodium Glutamate, medicine, Animals, Vasoconstrictor Agents, Obesity, Rats, Wistar, Pharmacology, Prostanoid, Acetylcholine, Potassium channel, Rats, 030104 developmental biology, Endocrinology, chemistry, 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid, Pinacidil, Prostaglandins, cardiovascular system, Food Additives, Sodium nitroprusside, Injections, Intraperitoneal, Muscle Contraction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b81080172e7403b19b0cbe51663ba1Test
    https://doi.org/10.1016/j.taap.2018.09.016Test


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  5. 5
    Inactivation of p66Shc Decreases Afferent Arteriolar KATP Channel Activity and Decreases Renal Damage in Diabetic Dahl SS Rats

    المؤلفون: Bradley S. Miller, Kevin D. Wright, Andrey Sorokin, Shoshana Blumenthal, John D. Imig, Alexander Staruschenko, Alexey Shalygin

    المصدر: Diabetes

    مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Src Homology 2 Domain-Containing, Transforming Protein 1, endocrine system diseases, Vasodilator Agents, Endocrinology, Diabetes and Metabolism, Vasodilation, 030204 cardiovascular system & hematology, Kidney, Diabetes Mellitus, Experimental, Diabetic nephropathy, Glibenclamide, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, KATP Channels, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Animals, Diabetic Nephropathies, Rats, Inbred Dahl, Pinacidil, nutritional and metabolic diseases, Kidney metabolism, medicine.disease, Streptozotocin, Rats, Arterioles, 030104 developmental biology, Endocrinology, chemistry, Rats, Transgenic, Glomerular hyperfiltration, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c22d4d50a3a1277b851775313c3d139Test
    https://doi.org/10.2337/db18-0308Test


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  6. 6
    Vascular KATP channels mitigate severe muscle O2 delivery-utilization mismatch during contractions in chronic heart failure rats

    المؤلفون: Jesse C. Craig, Trenton D. Colburn, Daniel M. Hirai, David C. Poole, Clark T. Holdsworth, Alexander J. Fees, Timothy I. Musch, Scott K. Ferguson

    المصدر: Respiratory Physiology & Neurobiology. 238:33-40

    مصطلحات موضوعية: Male, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Physiology, Myocardial Infarction, Blood Pressure, 030204 cardiovascular system & hematology, Article, Rats, Sprague-Dawley, Glibenclamide, 03 medical and health sciences, chemistry.chemical_compound, Oxygen Consumption, 0302 clinical medicine, KATP Channels, Heart Rate, Internal medicine, Administration, Inhalation, Heart rate, medicine, Animals, Heart Failure, Analysis of Variance, business.industry, General Neuroscience, Skeletal muscle, Oxygenation, medicine.disease, Rats, Oxygen, Disease Models, Animal, Blood pressure, medicine.anatomical_structure, chemistry, Anesthesia, Heart failure, Chronic Disease, Pinacidil, Cardiology, medicine.symptom, business, 030217 neurology & neurosurgery, Muscle Contraction, Muscle contraction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e579661d650b992c154cc18bf81a7eaTest
    https://doi.org/10.1016/j.resp.2017.01.009Test


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  7. 7
    The Opening of ATP-Sensitive K+ Channels Protects H9c2 Cardiac Cells Against the High Glucose-Induced Injury and Inflammation by Inhibiting the ROS-TLR4-Necroptosis Pathway

    المؤلفون: Meiji Chen, Jun Lan, Jianhao Li, Weijie Liang, Dongdan Zheng, Mingcai Song, Jianqiang Feng, Wenzhu Zhang

    المصدر: Cellular Physiology and Biochemistry, Vol 41, Iss 3, Pp 1020-1034 (2017)

    مصطلحات موضوعية: 0301 basic medicine, Indoles, Potassium Channels, Physiology, Apoptosis, lcsh:Physiology, Glyburide, Myocytes, Cardiac, lcsh:QD415-436, Receptor, K channels, chemistry.chemical_classification, Membrane Potential, Mitochondrial, Sulfonamides, lcsh:QP1-981, Pinacidil, Imidazoles, Cell biology, Biochemistry, Receptor-Interacting Protein Serine-Threonine Kinases, High glucose, Necroptosis, medicine.symptom, Signal Transduction, Cell signaling, ATP-sensitive K+ channel, Inflammation, Biology, H9c2 cardiac cells, Cell Line, lcsh:Biochemistry, 03 medical and health sciences, Necrosis, medicine, Animals, Reactive oxygen species, Diazoxide, Toll-like receptor 4, Acetylcysteine, Rats, Oxidative Stress, 030104 developmental biology, Glucose, chemistry, Gene Expression Regulation, TLR4, Hydroxy Acids, Decanoic Acids

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e2eaf02b7a4e67d8d5fda76438a38dTest
    http://www.karger.com/Article/FullText/461391Test


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  8. 8
    The effect of K+ channel opener pinacidil on the transmembrane potassi channel protein Kir4.1 of retinal Müller cells in vitro and diabetic rats

    المؤلفون: Wei Sun, Yan Luo, Shibo Tang, Tao Li, Shaofen Lin, Rong Tian, Manyun Xie, Hongjie Ma

    المصدر: Panminerva medica. 62(4)

    مصطلحات موضوعية: Ependymoglial Cells, Macular Edema, Capillary Permeability, chemistry.chemical_compound, Membrane Transport Modulators, Medicine, Animals, Potassium Channels, Inwardly Rectifying, Cells, Cultured, K channels, Retinal Muller Cells, Diabetic Retinopathy, business.industry, Pinacidil, Retinal Vessels, General Medicine, In vitro, Transmembrane protein, Rats, Disease Models, Animal, chemistry, Biophysics, Potassium, Channel (broadcasting), business, Signal Transduction

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dc36fef875f1021ed0ba6acca522ccTest
    https://pubmed.ncbi.nlm.nih.gov/31089080Test


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  9. 9
    Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway

    المؤلفون: Gi-Ja Lee, Weijian Li, Lamei Yu, Byung Mun Park, Suhn Hee Kim

    المصدر: Peptides. 121

    مصطلحات موضوعية: Male, Physiology, Biochemistry, Glibenclamide, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Atrial natriuretic peptide, KATP Channels, Glyburide, Anilides, Hydrogen Sulfide, Hypoxia, Monocrotaline, Pinacidil, NG-Nitroarginine Methyl Ester, cardiovascular system, medicine.symptom, Endothelin receptor, hormones, hormone substitutes, and hormone antagonists, Atrial Natriuretic Factor, medicine.drug, Signal Transduction, medicine.medical_specialty, Nitric Oxide Synthase Type III, Hypertension, Pulmonary, 030209 endocrinology & metabolism, Sodium hydrosulfide, Sulfides, 03 medical and health sciences, Cellular and Molecular Neuroscience, Organ Culture Techniques, Internal medicine, medicine, Potassium Channel Blockers, Animals, Secretion, Heart Atria, Activator (genetics), Bosentan, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, 2-Methoxyestradiol, Rats, Oxygen, PPAR gamma, chemistry, Gene Expression Regulation, 030217 neurology & neurosurgery

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0238222f13e354fd63ae42599c5dedc2Test
    https://pubmed.ncbi.nlm.nih.gov/31386893Test


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  10. 10
    ATP-sensitive potassium channels alleviate postoperative pain through JNK-dependent MCP-1 expression in spinal cord

    المؤلفون: Shi-Ren Shen, Jin-Qian Liu, Yong-Jing Gao, Su Cao, Xiang Zhu

    المصدر: International Journal of Molecular Medicine

    مصطلحات موضوعية: Male, Pain Threshold, medicine.medical_specialty, Pathology, endocrine system, chemokines, Sulfonylurea Receptors, chemistry.chemical_compound, Enzyme activator, KATP Channels, Internal medicine, Threshold of pain, Genetics, medicine, Animals, pinacidil, antinociception, Chemokine CCL2, Injections, Spinal, Pain Measurement, Pain, Postoperative, Oncogene, business.industry, astrocytes, JNK Mitogen-Activated Protein Kinases, adenosine triphosphate-sensitive potassium, General Medicine, Articles, Spinal cord, Adenosine, Potassium channel, skin/muscle incision and retraction, p-JNK, Rats, Enzyme Activation, Disease Models, Animal, Protein Transport, Endocrinology, medicine.anatomical_structure, chemistry, Gene Expression Regulation, Spinal Cord, Apoptosis, glibenclamide, Pinacidil, business, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50b004029c9f20ea5ab988bd7c3227cTest
    http://europepmc.org/articles/PMC4380206Test


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