-
1
المؤلفون: Soheila Fattahi, Zahra Khalifehzadeh-Esfahani, Mina Mohammad-Rezaei, Sahar Mafi, Morteza Jafarinia
المصدر: Immunologic Research
مصطلحات موضوعية: Sirolimus, mTOR inhibitors, COVID-19 Vaccines, SARS-CoV-2, TOR Serine-Threonine Kinases, Immunology, COVID-19, Review, COVID-19 Drug Treatment, Phosphatidylinositol 3-Kinases, PI3K/Akt/ mTOR pathway, Humans, Proto-Oncogene Proteins c-akt, Rapamycin
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04640203be7ba40bbc1ec8e0a5e6768Test
http://europepmc.org/articles/PMC8808470Test -
2
المؤلفون: Gunhild Sommer, Marie Matthes, Rebecca Waetzig, Johannes Leister, Selim Corbacioglu, Gina Penkivech, Tilman Heise
المصدر: International Journal of Medical Sciences
مصطلحات موضوعية: Indoles, Combination therapy, mTOR inhibitor, Cell Survival, medicine.medical_treatment, ATP competitive mTOR inhibitors, Dasatinib, P70-S6 Kinase 1, Irinotecan, combination therapy, 03 medical and health sciences, Inhibitory Concentration 50, neuroblastoma, 0302 clinical medicine, Neuroblastoma, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Temozolomide, Humans, Rapamycin, Naphthyridines, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, Chemotherapy, Dose-Response Relationship, Drug, business.industry, TOR Serine-Threonine Kinases, Thiourea, Torin-2, Drug Synergism, General Medicine, Cell cycle, medicine.disease, Pyrimidines, Purines, Administration, Metronomic, Cancer research, 030211 gastroenterology & hepatology, Drug Screening Assays, Antitumor, business, medicine.drug, Signal Transduction, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e96a3896cfaaa672126835c7932ea849Test
http://europepmc.org/articles/PMC7738968Test -
3
المؤلفون: Linda Partridge, Paula Juricic Dzankic
المصدر: Lancet Healthy Longev
The Lancet. Healthy Longevity, Vol 2, Iss 5, Pp e232-e233 (2021)
The Lancet. Healthy Longevityمصطلحات موضوعية: Aging, Health (social science), MEDLINE, Viral infection, Antiviral Agents, Pulmonary Disease, Chronic Obstructive, Text mining, Immunity, Medicine, Humans, Everolimus, Biology, Pandemics, Respiratory Tract Infections, Aged, rapamycin, business.industry, TOR Serine-Threonine Kinases, Comment, RC952-954.6, COVID-19, MTOR Inhibitors, Discovery and development of mTOR inhibitors, Clinical trial, Psychiatry and Mental health, Treatment Outcome, Diabetes Mellitus, Type 2, Geriatrics, Immunology, Geriatrics and Gerontology, Family Practice, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e35cc195be514d194fa3e628e648f19aTest
https://hdl.handle.net/21.11116/0000-000B-2D53-6Test -
4
المؤلفون: Bartłomiej Pawlik, Szymon Grabia, Urszula Smyczyńska, Wojciech Fendler, Izabela Dróżdż, Ewa Liszewska, Jacek Jaworski, Katarzyna Kotulska, Sergiusz Jóźwiak, Wojciech Młynarski, Joanna Trelińska
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 22; Pages: 14493
مصطلحات موضوعية: Sirolimus, microRNA, mTOR inhibitor, rapamycin, tuberous sclerosis, shTSC1 and shTSC2 cells, TOR Serine-Threonine Kinases, Organic Chemistry, MTOR Inhibitors, General Medicine, Catalysis, Cell Line, Computer Science Applications, Inorganic Chemistry, MicroRNAs, Tuberous Sclerosis, Humans, Physical and Theoretical Chemistry, Molecular Biology, Spectroscopy
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::174c450c3e6843300514abbca15b04b8Test
https://doi.org/10.3390/ijms232214493Test -
5
المساهمون: ANS - Cellular & Molecular Mechanisms, APH - Mental Health, APH - Aging & Later Life, Pathology, Graduate School
المصدر: Expert review of neurotherapeutics, 18(3), 185-201. Taylor and Francis Ltd.
مصطلحات موضوعية: 0301 basic medicine, mTOR inhibitors, tuberous sclerosis complex, Epileptogenesis, 03 medical and health sciences, Tuberous sclerosis, Epilepsy, 0302 clinical medicine, Tuberous Sclerosis, Animals, Humans, Medicine, Pharmacology (medical), PI3K/AKT/mTOR pathway, Everolimus, rapamycin, business.industry, TOR Serine-Threonine Kinases, General Neuroscience, epileptogenesis, everolimus, mTORopathies, malformations, Anticonvulsants, Signal Transduction, Discovery and development of mTOR inhibitors, medicine.disease, Settore MED/39, 030104 developmental biology, Neurology (clinical), business, human activities, Neuroscience, 030217 neurology & neurosurgery, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f85607f68c0fcbb9d482d93c0e8fce76Test
https://doi.org/10.1080/14737175.2018.1428562Test -
6
المؤلفون: Michela Campolo, Alessio Ardizzone, Marika Lanza, Marika Cordaro, Sarah Adriana Scuderi, Emanuela Esposito, Giovanna Casili, Salvatore Cuzzocrea, Alessia Filippone, Irene Paterniti
المصدر: Journal of Cellular and Molecular Medicine
مصطلحات موضوعية: Male, apoptosis, astrogliosis, behavioural performance, KU0063794, mTOR, mTORC1, mTORC2, neuroinflammation, neuronal death, rapamycin, traumatic brain injury, Necrosis, Traumatic brain injury, Morpholines, Pharmacology, Lesion, Mice, Brain Injuries, Traumatic, Medicine, Animals, Enzyme Inhibitors, Neuroinflammation, PI3K/AKT/mTOR pathway, Cell Proliferation, Neurons, Sirolimus, Cell Death, business.industry, TOR Serine-Threonine Kinases, Cell Biology, Original Articles, MTOR Inhibitors, medicine.disease, nervous system diseases, Astrogliosis, Disease Models, Animal, Pyrimidines, nervous system, Neuroinflammatory Diseases, Molecular Medicine, Original Article, medicine.symptom, business, Immunosuppressive Agents, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1e7c71b99995cf2489cffa15aef7feTest
http://hdl.handle.net/11570/3208354Test -
7
المؤلفون: Karolina Okła, Magdalena Dmoszyńska-Graniczka, Wiesława Bednarek, Marcin Bobiński, Pablo Garcia-Sanz, Rafał Tarkowski, Jarogniew J. Łuszczki, Jan Kotarski, Anna Wawruszak, Gema Moreno-Bueno
المصدر: International Journal of Medical Sciences
مصطلحات موضوعية: Leiomyosarcoma, mTOR inhibitors, Sarcoma, Endometrial Stromal, Deoxycytidine, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, isobolography, 0302 clinical medicine, Carcinosarcoma, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, MTT assay, carcinosarcomas, Sapanisertib, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, Endometrial stromal sarcoma, Uterine sarcoma, Chemistry, rapamycin, TOR Serine-Threonine Kinases, uterine sarcomas, gemcitabine, Drug Synergism, General Medicine, medicine.disease, Gemcitabine, Endometrial Neoplasms, body regions, Pyrimidines, Cancer research, mTOR, Pyrazoles, 030211 gastroenterology & hepatology, Female, Proto-Oncogene Proteins c-akt, medicine.drug, Signal Transduction, Research Paper
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d48257b82c6c1dc25dbaef4508c87ea0Test
https://pubmed.ncbi.nlm.nih.gov/33173419Test -
8
المؤلفون: Shunai Liu, Renfeng Li, Yunfeng Zheng
المصدر: Journal of Medical Virology
مصطلحات موضوعية: mTOR inhibitors, medicine.medical_treatment, coronavirus, Reviews, Review, Cross Reactions, medicine.disease_cause, Antibodies, Viral, Virus, Immunomodulation, 03 medical and health sciences, 0302 clinical medicine, cross‐reactive antibody, Immunity, Virology, medicine, Humans, Antibody-dependent enhancement, 030212 general & internal medicine, PI3K/AKT/mTOR pathway, Coronavirus, B-Lymphocytes, business.industry, rapamycin, Mortality rate, TOR Serine-Threonine Kinases, medicine.disease, immunity, Antibody-Dependent Enhancement, COVID-19 Drug Treatment, Clinical trial, Cytokine release syndrome, Cytokine, Infectious Diseases, Immunology, antibody‐dependent enhancement, cytokine storm, 030211 gastroenterology & hepatology, Cytokine storm, business, Cytokine Release Syndrome, ADE
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fde280a6982549836b9aa71b42c2c21dTest
http://europepmc.org/articles/PMC7272823Test -
9
المؤلفون: Franco Cortese, Darla Karpinsky-Semper, Alex Zhavoronkov, Leslie C. Jellen, Alexander Aliper, Artem V. Artemov, Andrew G. Swick, Alexey Moskalev
المصدر: Aging (Albany NY)
مصطلحات موضوعية: 0301 basic medicine, Aging, Computational biology, compound screening, Machine Learning, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Databases, Genetic, Drug Discovery, Screening method, Medicine, Humans, Gene Regulatory Networks, Molecular Targeted Therapy, Protein Interaction Maps, Protein Kinase Inhibitors, natural, Sirolimus, Molecular Structure, business.industry, rapamycin, TOR Serine-Threonine Kinases, Molecular Mimicry, deep learning, Computational Biology, Cell Biology, Experimental validation, Geroprotector, Discovery and development of mTOR inhibitors, Metformin, High-Throughput Screening Assays, 030104 developmental biology, Chronic disease, chemistry, 030220 oncology & carcinogenesis, Dietary Supplements, geroprotector, nutraceutical, Neural Networks, Computer, business, Isoliquiritigenin, medicine.drug, Research Paper, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4085f985e3077bd427a25233052bfc2bTest
http://europepmc.org/articles/PMC5723685Test -
10
المؤلفون: Chiara Lanzillotta, Antonella Tramutola, Fabio Di Domenico
المصدر: Expert Review of Neurotherapeutics. 17:33-45
مصطلحات موضوعية: 0301 basic medicine, autophagy, Cellular functions, Biology, 03 medical and health sciences, Therapeutic approach, 0302 clinical medicine, medicine, Humans, Cognitive Dysfunction, Pharmacology (medical), Molecular Targeted Therapy, Cognitive decline, PI3K/AKT/mTOR pathway, Mtor signaling, rapamycin, TOR Serine-Threonine Kinases, Alzheimer disease, mTOR, rapalogues, neuroscience (all), neurology (clinical), pharmacology (medical), General Neuroscience, Autophagy, Discovery and development of mTOR inhibitors, medicine.disease, 030104 developmental biology, Neurology (clinical), Alzheimer's disease, Neuroscience, 030217 neurology & neurosurgery
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d7edf2e005f57705fbe30968badbefTest
https://doi.org/10.1080/14737175.2017.1244482Test