نتائج البحث - "MTOR Inhibitors"

1

دورية أكاديمية

The role of sirolimus in the treatment of vascular anomalies.

المؤلفون: KOPEĆ, JAKUB¹ jdkopec@gmail.com, GAWŁOWSKA, ALEKSANDRA¹, KOPEĆ, EWA², PRZEWRATIL, PRZEMYSŁAW¹

المصدر: Family Medicine & Primary Care Review. 2022, Vol. 24 Issue 2, p168-171. 4p.

مصطلحات موضوعية: *RAPAMYCIN, *MTOR inhibitors, *BLOOD-vessel abnormalities, *LYMPHATIC abnormalities, *PHARMACODYNAMICS

2

دورية أكاديمية

Increased mTORC2 pathway activation in lymph nodes of iMCD‐TAFRO.

المؤلفون: Phillips, Alexis D., Kakkis, Joseph J., Tsao, Patricia Y., Pierson, Sheila K., Fajgenbaum, David C.

المصدر: Journal of Cellular & Molecular Medicine; Jun2022, Vol. 26 Issue 11, p3147-3152, 6p

مصطلحات موضوعية: LYMPH nodes, CASTLEMAN'S disease, THERAPEUTICS, LYMPHOPROLIFERATIVE disorders, RAPAMYCIN, MTOR inhibitors

مصطلحات جغرافية: ALPS

النص الكامل

3

دورية أكاديمية

The novel, catalytic mTORC1/2 inhibitor PQR620 and the PI3K/mTORC1/2 inhibitor PQR530 effectively cross the blood-brain barrier and increase seizure threshold in a mouse model of chronic epilepsy.

المؤلفون: Brandt, Claudia^1,2, Hillmann, Petra³, Noack, Andreas^1,2, Römermann, Kerstin^1,2, Öhler, Leon A.¹, Rageot, Denise⁴, Beaufils, Florent³, Melone, Anna⁴, Sele, Alexander M.⁴, Wymann, Matthias P.⁴, Fabbro, Doriano³, Löscher, Wolfgang^1,2 wolfgang.loescher@tiho-hannover.de

المصدر: Neuropharmacology. Sep2018, Vol. 140, p107-120. 14p.

مصطلحات موضوعية: *MTOR inhibitors, *TUBEROUS sclerosis, *BLOOD-brain barrier, *PHOSPHORYLATION, *EPILEPSY prevention, *THERAPEUTICS

4

دورية أكاديمية

Therapeutic potency of mTOR signaling pharmacological inhibitors in the treatment of proinflammatory diseases, current status, and perspectives.

المؤلفون: Soltani, Arash^1,2, Bahreyni, Amirhossein³, Boroumand, Nadia¹, Roshan, Mostafa karimi¹, Khazaei, Majid⁴, Ryzhikov, Mikhail⁵, Soleimanpour, Saman⁶, Avan, Amir^7,8 avana@mums.ac.ir, Hassanian, Seyed Mahdi^1,7,8,9 hasanianmehrm@mums.ac.ir

المصدر: Journal of Cellular Physiology. Jun2018, Vol. 233 Issue 6, p4783-4790. 8p.

مصطلحات موضوعية: *RAPAMYCIN, *MTOR inhibitors, *INFLAMMATION treatment, *ENERGY metabolism, *THERAPEUTICS

5

دورية أكاديمية

m- TOR inhibitors and their potential role in haematological malignancies.

المؤلفون: Calimeri, Teresa¹, Ferreri, Andrés J. M.¹ ferreri.andres@hsr.it

المصدر: British Journal of Haematology. Jun2017, Vol. 177 Issue 5, p684-702. 19p.

مصطلحات موضوعية: *MTOR inhibitors, *RAPAMYCIN, *EVEROLIMUS, *ANTINEOPLASTIC agents, *CANCER treatment, *LYMPHOMA treatment, *LEUKEMIA treatment, *THERAPEUTICS

6

دورية أكاديمية

The Role of mTOR Inhibitors in Hematologic Disease: From Bench to Bedside.

المؤلفون: Feng, Yimei, Chen, Xiaoli, Cassady, Kaniel, Zou, Zhongmin, Yang, Shijie, Wang, Zheng, Zhang, Xi

المصدر: Frontiers in Oncology; 1/8/2021, Vol. 11, pN.PAG-N.PAG, 15p

مصطلحات موضوعية: BLOOD diseases, MTOR inhibitors, GRAFT versus host disease, HEMATOLOGIC malignancies, THERAPEUTICS

النص الكامل

7

دورية أكاديمية

Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades.

المؤلفون: Pereira, Vitor Silva, Suavinha, Angélica C.D. Romano, Wegener, Gregers, Joca, Sâmia R.L.

المصدر: Acta Neuropsychiatrica; Jun2019, Vol. 31 Issue 3, p143-150, 8p

مصطلحات موضوعية: NITRIC-oxide synthases, KETAMINE, RAPAMYCIN, PROTEIN-tyrosine kinases, PREFRONTAL cortex, MTOR inhibitors, THERAPEUTICS

8

دورية أكاديمية

Combining the mammalian target of rapamycin inhibitor, rapamycin, with resveratrol has a synergistic effect in multiple myeloma.

المؤلفون: Jin, Hong-Guang, Wu, Guo-Zhen, Wu, Guo-Hua, Bao, Yong-Ge

المصدر: Oncology Letters; May2018, Vol. 15 Issue 5, p6257-6264, 8p

مصطلحات موضوعية: MULTIPLE myeloma treatment, RAPAMYCIN, RESVERATROL, MTOR inhibitors, COMBINATION drug therapy, THERAPEUTICS

النص الكامل

9

دورية أكاديمية

Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.

المؤلفون: Shen, Ying‐Qiang, Guerra‐Librero, Ana, Fernandez‐Gil, Beatriz I., Florido, Javier, García‐López, Sergio, Martinez‐Ruiz, Laura, Mendivil‐Perez, Miguel, Soto‐Mercado, Viviana, Acuña‐Castroviejo, Darío, Ortega‐Arellano, Hector, Carriel, Victor, Diaz‐Casado, María E., Reiter, Russel J., Rusanova, Iryna, Nieto, Ana, López, Luis C., Escames, Germaine

المصدر: Journal of Pineal Research; Apr2018, Vol. 64 Issue 3, p1-1, 18p

مصطلحات موضوعية: MELATONIN, RAPAMYCIN, HEAD & neck cancer treatment, MTOR inhibitors, APOPTOSIS, SQUAMOUS cell carcinoma, CELLULAR signal transduction, THERAPEUTICS

10

دورية أكاديمية

Extra-virgin olive oil contains a metabolo-epigenetic inhibitor of cancer stem cells.

المؤلفون: Corominas-Faja, Bruna, Cuyàs, Elisabet, Lozano-Sánchez, Jesús, Cufí, Sílvia, Verdura, Sara, Fernández-Arroyo, Salvador, Borrás-Linares, Isabel, Martin-Castillo, Begoña, Martin, Ángel G., Lupu, Ruth, Nonell-Canals, Alfons, Sanchez-Martinez, Melchor, Micol, Vicente, Joven, Jorge, Segura-Carretero, Antonio, Menendez, Javier A.

المصدر: Carcinogenesis; Apr2018, Vol. 39 Issue 4, p601-613, 13p

مصطلحات موضوعية: BREAST cancer treatment, CANCER stem cells, THERAPEUTIC use of olive oil, PHYTOCHEMICALS, MTOR inhibitors, EPIGENETICS, THERAPEUTICS

النص الكامل

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