دورية أكاديمية
Generating fit-for-purpose real-world evidence in Asia: How far are we from closing the gaps?
| العنوان: | Generating fit-for-purpose real-world evidence in Asia: How far are we from closing the gaps? |
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| المؤلفون: | Wen-Yi Shau, Sajita Setia, Salil Shinde, Handoko Santoso, Daniel Furtner |
| المصدر: | Perspectives in Clinical Research, Vol 14, Iss 3, Pp 108-113 (2023) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Medicine (General) |
| مصطلحات موضوعية: | asia, decision-making, health technology assessment, randomized controlled trials, real-world data, real-world evidence, Medicine, Medicine (General), R5-920 |
| الوصف: | Evidence generated by randomized controlled trials (RCTs) does not often represent the patient journey and clinical outcomes in the real world due to limited external validity or generalizability. Studies based on real-world data are intended to generalize results to the broader population; however, if the influence of external factors or confounders is not effectively managed, the cause-and-effect relationship and internal validity may be challenged, resulting in flawed results. The collection of quality real-world evidence (RWE) is crucial in Asia as there is often an underrepresentation of Asian populations in RCTs. In addition, few countries in Asia are catching up with the Western world in issuing practical foundational principles and guidance for conducting and adopting evidence for regulatory and reimbursement decisions. However, privacy and data protection laws are generally lagging behind technological developments in electronic medical records. While leveraging RWE in clinical and regulatory decision-making holds excellent potential, collective efforts across industry, governments, and research institutions are required for generating standardized practices and building capabilities for developing fit-for-purpose RWE in Asia. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2229-3485 |
| العلاقة: | http://www.picronline.org/article.asp?issn=2229-3485;year=2023;volume=14;issue=3;spage=108;epage=113;aulast=ShauTest; https://doaj.org/toc/2229-3485Test |
| DOI: | 10.4103/picr.picr_193_22 |
| الوصول الحر: | https://doaj.org/article/fe4ccffea5954793a1db60e85967365eTest |
| رقم الانضمام: | edsdoj.fe4ccffea5954793a1db60e85967365e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22293485 |
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| DOI: | 10.4103/picr.picr_193_22 |