دورية أكاديمية
Postoperative radiotherapy is associated with improved survival in pT1-2N1 oral and oropharyngeal cancer without adequate neck dissection
| العنوان: | Postoperative radiotherapy is associated with improved survival in pT1-2N1 oral and oropharyngeal cancer without adequate neck dissection |
|---|---|
| المؤلفون: | Ching-Chieh Yang, Bor-Hwang Kang, Wen-Shan Liu, Chun-Hao Yin, Ching-Chih Lee |
| المصدر: | Radiation Oncology, Vol 16, Iss 1, Pp 1-8 (2021) |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Oral cancer, Oropharyngeal cancer, Radiotherapy, Neck dissection, Survival, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Background To assess the benefit of postoperative radiotherapy in patients with pT1-2N1M0 oral and oropharyngeal cancer by the quality of neck dissection. Methods In the Surveillance, Epidemiology, and End Results database, pT1-2N1M0 oral and oropharyngeal cancer patients treated by primary tumor resection and neck dissection with or without radiotherapy were included between 2004 and 2015. Univariate and multivariate analysis were used to explore the effect of adjuvant radiotherapy on 5-year overall survival (OS) and disease-specific survival (DSS) among different quality of neck dissection. Results Of the 1765 patients identified, 1108 (62.8%) had oral cancer, 1141 (64.6%) were men, and 1067 (60.5%) underwent adjuvant radiotherapy. After adjusting for confounding factors, postoperative radiotherapy reduced the adjusted hazard ratio (aHR) of 5-year OS to 0.64 (95% confidence interval [CI] 0.49–0.84) in those with |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1748-717X |
| العلاقة: | https://doaj.org/toc/1748-717XTest |
| DOI: | 10.1186/s13014-020-01736-8 |
| الوصول الحر: | https://doaj.org/article/45a175db0cb64441bcbc3123c1cdcbf4Test |
| رقم الانضمام: | edsdoj.45a175db0cb64441bcbc3123c1cdcbf4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1748717X |
|---|---|
| DOI: | 10.1186/s13014-020-01736-8 |