دورية أكاديمية
Antimicrobial Susceptibility of Clinical Oral Isolates of Actinomyces spp.
العنوان: | Antimicrobial Susceptibility of Clinical Oral Isolates of Actinomyces spp. |
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المؤلفون: | Alexandra Wolff, Arne C. Rodloff, Paul Vielkind, Toralf Borgmann, Catalina-Suzana Stingu |
المصدر: | Microorganisms, Vol 10, Iss 125, p 125 (2022) |
بيانات النشر: | MDPI AG |
سنة النشر: | 2022 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | Actinomyces, susceptibility testing, agar dilution, E-Test, Biology (General), QH301-705.5 |
الوصف: | Actinomyces species play an important role in the pathogenesis of oral diseases and infections. Susceptibility testing is not always routinely performed, and one may oversee a shift in resistance patterns. The aim of the study was to analyze the antimicrobial susceptibility of 100 well-identified clinical oral isolates of Actinomyces spp. against eight selected antimicrobial agents using the agar dilution (AD) and E-Test (ET) methods. We observed no to low resistance against penicillin, ampicillin-sulbactam, meropenem, clindamycin, linezolid and tigecycline (0–2% ET, 0% AD) but high levels of resistance to moxifloxacin (93% ET, 87% AD) and daptomycin (83% ET, 95% AD). The essential agreement of the two methods was very good for benzylpenicillin (EA 95%) and meropenem (EA 92%). The ET method was reliable for correctly categorizing susceptibility, in comparison with the reference method agar dilution, except for daptomycin (categorical agreement 87%). Penicillin is still the first-choice antibiotic for therapy of diseases caused by Actinomyces spp. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2076-2607 |
العلاقة: | https://www.mdpi.com/2076-2607/10/1/125Test; https://doaj.org/toc/2076-2607Test; https://doaj.org/article/7b07ddd983f948a79d287b651a23b866Test |
DOI: | 10.3390/microorganisms10010125 |
الإتاحة: | https://doi.org/10.3390/microorganisms10010125Test https://doaj.org/article/7b07ddd983f948a79d287b651a23b866Test |
رقم الانضمام: | edsbas.41C24CD1 |
قاعدة البيانات: | BASE |
تدمد: | 20762607 |
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DOI: | 10.3390/microorganisms10010125 |