نتائج البحث - "mitochondrial outer membrane permeabilization"

1

Mitochondrial outer membrane permeabilization at the single molecule level

المؤلفون: Andreas Jenner, Ana J. García-Sáez, Shashank Dadsena

المصدر: Cellular and Molecular Life Sciences

مصطلحات موضوعية: Single-molecule techniques, Programmed cell death, Mitochondrial outer membrane permeabilization (MOMP), Apoptosis, Review, urologic and male genital diseases, Permeability, Molecular Imprinting, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Interaction network, Bcl-2 proteins, Protein Interaction Mapping, Fluorescence Resonance Energy Transfer, Animals, Humans, Protein Interaction Maps, Molecular Biology, Tissue homeostasis, 030304 developmental biology, Pharmacology, 0303 health sciences, Mitochondrial outer membrane permeabilization, Mechanism (biology), Chemistry, Intrinsic apoptotic pathway, Cell Biology, bacterial infections and mycoses, female genital diseases and pregnancy complications, Cell biology, Mitochondria, Proto-Oncogene Proteins c-bcl-2, Apoptotic cell death, Molecular Medicine, bacteria, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72b9cc4cabb7e0a4470d199f71f3046Test
http://europepmc.org/articles/PMC8106609Test

2

Regulation of Apoptosis by the Bcl-2 Family of Proteins: Field on a Brink

المؤلفون: Alexey S. Ladokhin

المصدر: Cells
Cells, Vol 9, Iss 2121, p 2121 (2020)

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, 2019-20 coronavirus outbreak, protein–membrane interactions, Antineoplastic Agents, Biology, Pathogenesis, Bcl-2 proteins as therapeutic targets, 03 medical and health sciences, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, cancer, lcsh:QH301-705.5, mitochondrial outer membrane permeabilization, Sulfonamides, Mitochondrial outer membrane permeabilization, Bcl-2 family, apoptosis, Cancer, General Medicine, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Mitochondria, Cell biology, Gene Expression Regulation, Neoplastic, Editorial, 030104 developmental biology, lcsh:Biology (General), Proto-Oncogene Proteins c-bcl-2, Apoptosis, 030220 oncology & carcinogenesis, Mitochondrial Membranes, Homeostasis, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98367e38fd5d6ea860d79dbb9034c297Test
https://doi.org/10.3390/cells9092121Test

3

Counting on Death : Quantitative aspects of Bcl-2 family regulation

المؤلفون: Annika Hantusch, Markus Rehm, Thomas Brunner

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655e20bef10da34b92077a08109aaa40Test

4

The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved?

المؤلفون: Xu Luo, Katelyn L. O'Neill, Kai Huang

المصدر: F1000Research

مصطلحات موضوعية: BH3 mimetics, Cell, Apoptosis, Bcl-xL, Review, Mutually exclusive events, General Biochemistry, Genetics and Molecular Biology, Membrane-mediated Spontaneous activation, Bid, Bcl-2 family, medicine, Bad, Activator, Humans, Bim, General Pharmacology, Toxicology and Pharmaceutics, retro-translocation, bcl-2-Associated X Protein, Mitochondrial outer membrane permeabilization, General Immunology and Microbiology, biology, Effector, Chemistry, Activator (genetics), BH3-only proteins, Bak, Direct activation, Mcl-1, Articles, General Medicine, Indirect activation, Cell biology, Sensitizer, de novo activation, Mitochondrial outer membrane, bcl-2 Homologous Antagonist-Killer Protein, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, Bax, biology.protein, biological phenomena, cell phenomena, and immunity, auto-activation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0434affb0eb4fe195a5c3717977f4b7cTest
https://doi.org/10.12688/f1000research.25607.1Test

5

Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering

المؤلفون: Joerg Stetefeld, Joanna Rzeszowska-Wolny, Mayur V. Jain, Artur Cieślar-Pobuda, Wiem Chaabane, Saeid Ghavami, Marek J. Łos, Mohamed El-Gazzah, Mehrdad Rafat

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 9, Pp 679-693 (2014)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Cytoplasm, Cancer Research, TMRM, Tetramethylrhodamine methyl ester perchlorate0, HGV-Apoptin, Human gyrovirus apoptin, Apoptosis, MOMP, Mitochondrial outer membrane permeabilization, Mitochondrial apoptosis-induced channel, AIF, Nur77, Annan medicinsk grundvetenskap, AIF, Apoptosis inducing factor, Nuclear Receptor Subfamily 4, Group A, Member 1, Gyrovirus, BCL-XL, B-cell lymphoma extra-large, DISC, Death-inducing signal complex, FADD, Other Basic Medicine, Membrane Potential, Mitochondrial, biology, Apoptosis Inducing Factor, Cytochromes c, virus diseases, Receptors, Death Domain, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, mitochondrial pathway, Mitochondria, Cell biology, Protein Transport, Proto-Oncogene Proteins c-bcl-2, Caspases, Apoptosis-inducing factor, Signal Transduction, CAV-Apoptin, Chicken anemia virus apoptin, Programmed cell death, cyt c, cytochrome c, caspase, Bcl-xL, Models, Biological, lcsh:RC254-282, Article, Cell Line, Viral Proteins, death receptors, Humans, 7AAD, 7-amino-actinomycin D, FADD, Fas-associated death domain, Death domain, Intrinsic apoptosis, MEF, Mouse embryonic fibroblast, cytc, digestive system diseases, Apoptin, biology.protein, Apoptosome

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff91e1764b6bc1727600d6c646b3f55Test
https://doi.org/10.1016/j.neo.2014.08.001Test

6

Bax, Bak and beyond - mitochondrial performance in apoptosis

المؤلفون: Ana J. García-Sáez, Aida Peña-Blanco

المصدر: The FEBS journal. 285(3)

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Lipid Bilayers, Apoptosis, Biology, Mitochondrion, Biochemistry, Mitochondrial Dynamics, Mitochondrial Membrane Transport Proteins, Models, Biological, 03 medical and health sciences, Organelle, Animals, Humans, Protein Interaction Domains and Motifs, Molecular Biology, bcl-2-Associated X Protein, Mitochondrial outer membrane permeabilization, Bcl-2 family, Lipid Mobilization, Cell Biology, Cell biology, Mitochondria, 030104 developmental biology, bcl-2 Homologous Antagonist-Killer Protein, Proto-Oncogene Proteins c-bcl-2, Mitochondrial Membranes, Molecular mechanism, biological phenomena, cell phenomena, and immunity, Protein Multimerization, Bacterial outer membrane, Apoptosis Regulatory Proteins, Dimerization, Porosity, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7c8198ea856de35493a758dc01f311aTest
https://pubmed.ncbi.nlm.nih.gov/28755482Test

7

The mitochondrial death pathway: a promising therapeutic target in diseases

المؤلفون: Sanjeev Gupta, George E.N. Kass, Eva Szegezdi, Bertrand Joseph

المصدر: Journal of Cellular and Molecular Medicine

مصطلحات موضوعية: Mitochondrial Diseases, bcl-2, amyotrophic-lateral-sclerosis, Reviews, Cellular homeostasis, Mitochondrion, Biology, Models, Biological, Mitochondrial apoptosis-induced channel, cytochrome-c release, peripheral benzodiazepine-receptor, apoptosis-inducing factor, etoposide-induced apoptosis, Animals, Humans, bcl-2 family-members, adenine-nucleotide translocator, bcl-2-Associated X Protein, mitochondrial outer membrane permeabilization, programmed cell-death, Membrane Potential, Mitochondrial, permeability transition pore, Bcl-2 family, apoptosis, Cell Biology, Mitochondria, Cell biology, Proto-Oncogene Proteins c-bcl-2, caspases, electron-transport chain, mitochondrial fusion, Mitochondrial permeability transition pore, DNAJA3, Molecular Medicine, Apoptosome, Signal Transduction, mitochondrial permeability transition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec68702ae94c60ab920038189210eb7Test
https://doi.org/10.1111/j.1582-4934.2009.00697.xTest

8

Robustness analysis identifies the plausible model of the Bcl-2 apoptotic switch

المؤلفون: Chun Chen, Jun Cui, Pingping Shen, Wei Zhang

المصدر: FEBS Letters. 581:5143-5150

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e00a74776579e9372ee536ccf7a86c0fTest
https://doi.org/10.1016/j.febslet.2007.09.063Test

9

Embedded together: The life and death consequences of interaction of the Bcl-2 family with membranes

المؤلفون: Jialing Lin, David W. Andrews, Brian Leber

المصدر: Apoptosis. 12:897-911

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d608a16b009491359a896d61fc5ea825Test
https://doi.org/10.1007/s10495-007-0746-4Test

10

Optimization and validation of mitochondria-based functional assay as a useful tool to identify BH3-like molecules selectively targeting anti-apoptotic Bcl-2 proteins

المؤلفون: Jianting Long, Shaomeng Wang, Liu Liu, Sanjeev Shangary, Shenming Wang, Han Yi, Zaneta Nikolovska-Coleska

المصدر: BMC Biotechnology

مصطلحات موضوعية: Cytochrome, Blotting, Western, Mitochondrial outer membrane permeabilization (MOMP), bcl-X Protein, Apoptosis, Breast Neoplasms, Mitochondrion, Biology, Mitochondrial Proteins, Cell Line, Tumor, Bcl-2 homolog domain 3 (BH3), Humans, Cell-Free System, Cytochrome c, Bcl-2 family, Intracellular Signaling Peptides and Proteins, Cytochromes c, Reproducibility of Results, Surface Plasmon Resonance, Mitochondria, Cell biology, Blot, B cell lymphoma 2 (Bcl-2), Proto-Oncogene Proteins c-bcl-2, Cancer cell, biology.protein, Myeloid Cell Leukemia Sequence 1 Protein, Female, bcl-Associated Death Protein, biological phenomena, cell phenomena, and immunity, Apoptosis Regulatory Proteins, Bacterial outer membrane, Research Article, BH3 Interacting Domain Death Agonist Protein, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816ae39576e9a7550495cd7e4aec234eTest
https://doi.org/10.1186/1472-6750-13-45Test

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