The SdTo clarify the molecular basis of SdA short cis-regulatory region restricted to the -72 to +12 area upstream of the B4GALNT2 short-type transcript variant contained the essential promoter activity that drives the expression of the human B4GALNT2 regardless of the cell type. We further showed that B4GALNT2 transcriptional activation mostly requires ETS1 and to a lesser extent SP1.Results presented herein are expected to provide clues to better understand B4GALNT2 regulatory mechanisms.
