المؤلفون: Rotow, Julia K, Gui, Philippe, Wu, Wei, Raymond, Victoria M, Lanman, Richard B, Kaye, Frederic J, Peled, Nir, de la Cruz, Ferran Fece, Nadres, Brandon, Corcoran, Ryan B, Yeh, Iwei, Bastian, Boris C, Starostik, Petr, Newsom, Kimberly, Olivas, Victor R, Wolff, Alexander M, Fraser, James S, Collisson, Eric A, McCoach, Caroline E, Camidge, D Ross, Pacheco, Jose, Bazhenova, Lyudmila, Li, Tianhong, Bivona, Trever G, Blakely, Collin M

المصدر: Clinical Cancer Research. 26(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Lung, Lung Cancer, Cancer, Clinical Research, Genetics, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Good Health and Well Being, Aged, Animals, Biomarkers, Tumor, Carcinoma, Non-Small-Cell Lung, Cell-Free Nucleic Acids, Crizotinib, Exons, Female, Humans, Lung Neoplasms, MAP Kinase Signaling System, Male, Mice, Mice, Inbred BALB C, Middle Aged, Molecular Targeted Therapy, Mutation, Oncogene Protein p21(ras), Protein Kinase Inhibitors, Proto-Oncogene Proteins c-met, Treatment Outcome, Tumor Cells, Cultured, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7h86r6frTest

المؤلفون: Goyal, Lipika, Shi, Lei, Liu, Leah Y, de la Cruz, Ferran Fece, Lennerz, Jochen K, Raghavan, Srivatsan, Leschiner, Ignaty, Elagina, Liudmila, Siravegna, Giulia, Ng, Raymond WS, Vu, Phuong, Patra, Krushna C, Saha, Supriya K, Uppot, Raul N, Arellano, Ron, Reyes, Stephanie, Sagara, Takeshi, Otsuki, Sachie, Nadres, Brandon, Shahzade, Heather A, Dey-Guha, Ipsita, Fetter, Isobel J, Baiev, Islam, Van Seventer, Emily E, Murphy, Janet E, Ferrone, Cristina R, Tanabe, Kenneth K, Deshpande, Vikram, Harding, James J, Yaeger, Rona, Kelley, Robin K, Bardelli, Alberto, Iafrate, A John, Hahn, William C, Benes, Cyril H, Ting, David T, Hirai, Hiroshi, Getz, Gad, Juric, Dejan, Zhu, Andrew X, Corcoran, Ryan B, Bardeesy, Nabeel

المصدر: Cancer Discovery. 9(8)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Genetics, Adenosine Triphosphate, Adult, Aged, Cell Line, Tumor, Cholangiocarcinoma, Circulating Tumor DNA, Drug Resistance, Neoplasm, Female, Humans, Male, Middle Aged, Mutation, Oncogene Proteins, Fusion, Phenylurea Compounds, Protein Kinase Inhibitors, Pyrimidines, Receptor, Fibroblast Growth Factor, Type 2, Signal Transduction, Structure-Activity Relationship, Tomography, X-Ray Computed, Biochemistry and cell biology, Oncology and carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0z0563vtTest

المؤلفون: Corcoran, Ryan B, André, Thierry, Atreya, Chloe E, Schellens, Jan HM, Yoshino, Takayuki, Bendell, Johanna C, Hollebecque, Antoine, McRee, Autumn J, Siena, Salvatore, Middleton, Gary, Muro, Kei, Gordon, Michael S, Tabernero, Josep, Yaeger, Rona, O'Dwyer, Peter J, Humblet, Yves, De Vos, Filip, Jung, A Scott, Brase, Jan C, Jaeger, Savina, Bettinger, Severine, Mookerjee, Bijoyesh, Rangwala, Fatima, Van Cutsem, Eric

المصدر: Cancer Discovery. 8(4)

مصطلحات موضوعية: Digestive Diseases, Colo-Rectal Cancer, Cancer, Good Health and Well Being, Antineoplastic Combined Chemotherapy Protocols, Colorectal Neoplasms, Drug Resistance, Neoplasm, ErbB Receptors, Female, Humans, Imidazoles, MAP Kinase Signaling System, Male, Mitogen-Activated Protein Kinase Kinases, Oximes, Panitumumab, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf, Pyridones, Pyrimidinones, Oncology and Carcinogenesis

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7kb6t0ktTest

المؤلفون: Ebi, Hiromichi^1,2, Corcoran, Ryan B.^1,2, Singh, Anurag^1,2, Zhao Chen^2,3, Song, Youngchul¹, Lifshits, Eugene¹, Ryan, David P.^1,2, Meyerhardt, Jeffrey A.^2,3 jengelman@partners.org, Benes, Cyril^1,2, Settleman, Jeffrey^1,2, Wong, Kwok.-Kin.^2,3, Cantley, Lewis C.^2,4, Engelman, Jeffrey A.^1,2, Chen, Zhao (AUTHOR)

المصدر: Journal of Clinical Investigation. Nov2011, Vol. 121 Issue 11, p4311-4231. 11p. 1 Black and White Photograph, 1 Diagram, 1 Chart, 4 Graphs.

مصطلحات موضوعية: *PHOSPHOINOSITIDES, *RAS oncogenes, *COLON cancer, *CANCER cells, *WESTERN immunoblotting, *APOPTOSIS, *LABORATORY mice, *ANIMAL experimentation, *CELL lines, *CELLULAR signal transduction, *COLON tumors, *DNA probes, *GENETIC techniques, *MICE, *GENETIC mutation, *NUCLEOTIDES, *PHOSPHOTRANSFERASES, *PROTEINS, *RESEARCH funding, *RNA, *TRANSFERASES, *XENOGRAFTS, *PROTEIN kinase inhibitors, *CHEMICAL inhibitors, *PHARMACODYNAMICS, RECTUM tumors