المؤلفون: Randall C. Mazzarino, David Patterson, Terry G. Wilkinson, Marie Zikanova, Guido N. Vacano, Veronika Baresova, Nathan Duval

المصدر: Molecular Genetics and Metabolism Reports, Vol 25, Iss, Pp 100642-(2020)
Molecular Genetics and Metabolism Reports

مصطلحات موضوعية: AMP-activated protein kinase, (AMPK), 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase, (ATIC), Ribonucleotide, Mutant, adenosine triphosphate, (ATP), interferon, (INF), false discovery rate, (FDR), 5-formamido-4-imidazolecarboxamide ribonucleotide, (FAICAR), Transcriptome, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, 5-aminoimidazole-4-carboxamide ribonucleoside, (AICAr), cytochrome, P450 (CYP), Purine metabolism, lcsh:QH301-705.5, minus adenine crATIC to minus adenine WT comparison, (MM), mammalian Target of Rapamycin, (mTOR), 2. Zero hunger, 0303 health sciences, lcsh:R5-920, adenylosuccinate lyase, (ADSL), arachidonic acid, (AA), 5-aminoimidazole-4-carboxamide ribonucleotide, (ZMP), Alzheimer's disease, adenosine monophosphate, (AMP), Cell biology, fetal calf macroserum, (FCM), de novo purine synthesis, (DNPS), phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase, (PAICS), phospholipase, (PLA), Purine synthesis, cytosolic phospholipase A2, (cPLA2), Cellular model, lcsh:Medicine (General), Research Paper, Inosine monophosphate, Adenosine monophosphate, inosine monophosphate, (IMP), fragments per kilobase of exon per million reads mapped, (FPKM), fatty acid amide hydrolase, (FAAH), Development, gene ontology, (GO), cyclooxygenase, (COX), 03 medical and health sciences, Genetics, AICA-ribosiduria, Protein kinase A, Molecular Biology, 030304 developmental biology, adenine phosphoribosyltransferase, (APRT), Activator (genetics), phosphoribosyl pyrophosphate, (PRPP), xanthine monophosphate, (XMP), lipoxygenase, (LOX), Tuberous Sclerosis Complex 1 and 2, (TSC1 and TSC2), chemistry, lcsh:Biology (General), guanosine monophosphate, (GMP), differentially expressed gene, (DEG), fetal calf serum, (FCS), RNA-seq, plus adenine crATIC to plus adenine WT comparison, (PP), 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95de86e40273be28948ec47e4fa479b3Test
http://www.sciencedirect.com/science/article/pii/S2214426920300884Test

المؤلفون: Ying Cao, Chuang Zhang, Yonggang Ma, Jianhong Gu, Hongyan Zhao, Zongping Liu, Xi-Shuai Tong, Dong Wang, Jianchun Bian, Ruilong Song

المصدر: Cell Proliferation

مصطلحات موضوعية: musculoskeletal diseases, 0301 basic medicine, Cellular differentiation, AMP‐activated protein kinase (AMPK), ribosomal protein S6 kinase beta‐1 (p70S6K), 03 medical and health sciences, 0302 clinical medicine, Osteoprotegerin, AMP-activated protein kinase, Osteoclast, medicine, Protein kinase A, PI3K/AKT/mTOR pathway, biology, Chemistry, mammalian target of rapamycin (mTOR), Autophagy, AMPK, Original Articles, Cell Biology, General Medicine, Cell biology, osteoclasts, 030104 developmental biology, medicine.anatomical_structure, osteoprotegerin, 030220 oncology & carcinogenesis, biology.protein, Original Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fee2af512a5d92a51a40318b8fbf16aTest
https://doi.org/10.1111/cpr.12714Test

المؤلفون: José L. Quiles, Ángel J. De la Rosa, José L. Mauriz, Francisco J. Padillo, Raúl González, José M. Fuentes, Jesús de la Cruz, Javier González-Gallego, Elena Navarro-Villarán, Raquel Ordóñez, L.M. Marín-Gómez, Jordi Muntané, Mario Rodríguez-Arribas, María A. Rodríguez-Hernández, J.M. Álamo-Martínez, Paloma Gallego, Laura Contreras, José A Del Campo

المساهمون: Universidad de Sevilla. Departamento de Genética

المصدر: idUS. Depósito de Investigación de la Universidad de Sevilla
instname

مصطلحات موضوعية: 0301 basic medicine, Sorafenib, Cell signaling, autophagy, Physiology, Clinical Biochemistry, Apoptosis, 03 medical and health sciences, Mice, 0302 clinical medicine, Downregulation and upregulation, Autophagy, medicine, Biomarkers, Tumor, Animals, Humans, Bcl-2, Protein kinase A, Protein kinase B, PI3K/AKT/mTOR pathway, Chemistry, Caspase 3, mammalian target of rapamycin (mTOR), Liver Neoplasms, apoptosis, JNK Mitogen-Activated Protein Kinases, Cell Biology, Hep G2 Cells, Endoplasmic Reticulum Stress, 5′AMP-activated protein kinase (AMPK), Xenograft Model Antitumor Assays, Neoplasm Proteins, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Unfolded protein response, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Transcription Factor CHOP, medicine.drug, Signal Transduction

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13faddb9a0c020090635a3ed453ddd5eTest
https://hdl.handle.net/10668/12863Test

المؤلفون: Min-Bin Chen, Chao Ji, Mu-Xin Wei, Wen-Ting Li, Pei-Hua Lu, Mian-Hua Wu

المصدر: Oncotarget

مصطلحات موضوعية: Male, 0301 basic medicine, Antineoplastic Agents, Apoptosis, Mice, SCID, mTORC1, AMP-Activated Protein Kinases, colorectal cancer (CRC), Oldenlandia diffusa (OD) extracts (ODE), Oldenlandia, Mice, 03 medical and health sciences, 0302 clinical medicine, AMP-activated protein kinase, Downregulation and upregulation, AMP-activated protein kinase (AMPK), Cell Line, Tumor, Animals, Humans, Cytotoxic T cell, Medicine, Protein kinase A, biology, Traditional medicine, Plant Extracts, business.industry, AMPK, Middle Aged, Xenograft Model Antitumor Assays, p53 and mammalian target of rapamycin (mTOR), 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, biology.protein, Cancer research, Signal transduction, Colorectal Neoplasms, business, Research Paper, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd839979311f125269dea921e2cfe2ffTest
https://doi.org/10.18632/oncotarget.9969Test

المؤلفون: Shuai Ma, Xiaoping Wang, Bin Huang, Xiaojia Li

المصدر: Translational Neuroscience
Translational Neuroscience, Vol 7, Iss 1, Pp 50-55 (2016)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, P70-S6 Kinase 1, Substance P, Spinal cord injury, Pharmacology, Calcitonin gene-related peptide, Neuropathic pain, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Medicine, Protein kinase A, PI3K/AKT/mTOR pathway, Mammalian target of rapamycin (mTOR) protein kinase, business.industry, General Neuroscience, medicine.disease, chemistry, 030220 oncology & carcinogenesis, Anesthesia, Phosphorylation, business, 030217 neurology & neurosurgery, RC321-571, Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e559ec42a351f7c4e5f7afbc92b7d7Test
http://europepmc.org/articles/PMC5234518Test

المؤلفون: Dihui Ma, Xiao-Liang Liu, Chi Ma, Hai-Xia Hu, Xiao-Ming Jiang, Guangjian Li, Xu Wang

المصدر: Translational Neuroscience, Vol 7, Iss 1, Pp 151-157 (2016)
Translational Neuroscience

مصطلحات موضوعية: 0301 basic medicine, Cell signaling, caspase-3, hippocampus, Caspase 3, P70-S6 Kinase 1, Neurosciences. Biological psychiatry. Neuropsychiatry, pro-inflammatory cytokines, Proinflammatory cytokine, 03 medical and health sciences, 0302 clinical medicine, mammalian target of rapamycin (mtor), Medicine, Protein kinase A, PI3K/AKT/mTOR pathway, business.industry, General Neuroscience, alzheimer’s disease, 030104 developmental biology, Cancer research, Phosphorylation, Signal transduction, business, 030217 neurology & neurosurgery, Research Article, RC321-571

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1638ca48f28a98d1f6c5ad32b0b647Test
https://doaj.org/article/7014cd78adb44dbb938e073dc8f38040Test

المؤلفون: Paola Muti, Gregory R. Steinberg, Bruce E. Kemp, Andrew J. O'Brien, Vanessa P. Houde, Linda Villani, Theodoros Tsakiridis, Giovanni Blandino, Sandra Galic, Lindsay A. Broadfield

مصطلحات موضوعية: Male, Lung Neoplasms, Sodium Salicylate, AMP-Activated Protein Kinases, Biochemistry, chemistry.chemical_compound, Mice, AMP-activated protein kinase, Mice, Knockout, Aspirin, biology, Anti-Inflammatory Agents, Non-Steroidal, mammalian target of rapamycin (mTOR), Drug Synergism, Metformin, Neoplasm Proteins, Lipogenesis, Female, medicine.drug, acetyl-CoA carboxylase (ACC), medicine.medical_specialty, Cell Survival, aspirin, proliferation, fatty acids, Internal medicine, Cell Line, Tumor, medicine, Animals, Humans, Hypoglycemic Agents, Protein kinase A, Molecular Biology, Sodium salicylate, Fatty acid synthesis, Binding Sites, AMPK, Prostatic Neoplasms, cholesterol, Cell Biology, Fibroblasts, Embryo, Mammalian, Enzyme Activation, Endocrinology, chemistry, biology.protein, Cancer research, 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase, Acetyl-CoA Carboxylase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69fa08a800d2106d31457a94d70f7df9Test
https://acuresearchbank.acu.edu.au/item/8825v/salicylate-activates-ampk-and-synergizes-with-metformin-to-reduce-the-survival-of-prostate-and-lung-cancer-cells-ex-vivo-through-inhibition-of-de-novo-lipogenesisTest

المؤلفون: Suhua Zhu, Qing-Ping Li, Xiaowei Wu, Hong-Yi Zhu, Liang Hu, Maojuan Hao

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 18; Issue 3; Pages: 614
International Journal of Molecular Sciences, Vol 18, Iss 3, p 614 (2017)

مصطلحات موضوعية: Male, 0301 basic medicine, Nitric Oxide Synthase Type I, AMP-Activated Protein Kinases, lcsh:Chemistry, Mice, Ischemic Postconditioning, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, TOR Serine-Threonine Kinases, mammalian target of rapamycin (mTOR), General Medicine, Mitochondria, Computer Science Applications, Cell biology, Reperfusion Injury, cardiovascular system, Signal Transduction, medicine.drug, autophagy, adenosine monophosphate-activated protein kinase (AMPK), medicine.medical_specialty, Article, Catalysis, Cell Line, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Animals, Physical and Theoretical Chemistry, Protein kinase A, ischemic postconditioning (IPostC), ischemia/reperfusion, neuronal nitric oxide synthase (nNOS), Molecular Biology, PI3K/AKT/mTOR pathway, Reactive oxygen species, Myocardium, Organic Chemistry, Autophagy, AMPK, medicine.disease, Adenosine, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, chemistry, Apoptosis, Reperfusion injury

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b699fa81934a03619a9805f733e92b6dTest
https://doi.org/10.3390/ijms18030614Test

المؤلفون: Ying Yan, Haiyan Wu, Jonathan M. Backer, Rory J. Flinn, Rachel S. Schnur

المصدر: Biochemical Journal

مصطلحات موضوعية: mammalian vacuolar protein sorting 34 (Vps34), Biochemistry, chemistry.chemical_compound, Phosphatidylinositol 3-Kinases, MEM, minimal essential medium, Cricetinae, S6K1, S6 kinase 1, Threonine, Vacuolar protein sorting, 0303 health sciences, CaM, calmodulin, HA, haemagglutinin, biology, 030302 biochemistry & molecular biology, mammalian target of rapamycin (mTOR), TOR, target of rapamycin, UV radiation resistance-associated gene (UVRAG), Cell biology, UVRAG, UV radiation resistance-associated gene, beclin-1, FBS, foetal bovine serum, D-PBS, Dulbecco's PBS, PI3K, phosphoinositide 3-kinase, Signal Transduction, Research Article, autophagy, Calmodulin, Bif-1, Bax-interacting factor 1, hVps15, mammalian vacuolar protein sorting 15 homologue, Vps, vacuolar protein sorting, UVRAG, CHO Cells, mTOR, mammalian target of rapamycin, Protein Serine-Threonine Kinases, hVps34, mammalian vacuolar protein sorting 34 homologue, Vacuolar Sorting Protein VPS15, 03 medical and health sciences, HEK, human embryonic kidney, Cricetulus, BAPTA, Animals, Humans, MLCK, myosin light-chain kinase, Protein kinase A, Molecular Biology, 030304 developmental biology, Binding Sites, Endosomal Sorting Complexes Required for Transport, vacuolar protein sorting 15 (Vps15), Tumor Suppressor Proteins, Membrane Proteins, Cell Biology, YFP, yellow fluorescent protein, EGTA, BAPTA, 1,2-bis-(o-aminophenoxy)ethane-N,N,N′,N′-tetra-acetic acid, BAPTA/AM, BAPTA(acetoxymethyl ester), chemistry, biology.protein, Apoptosis Regulatory Proteins

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7b2a29457b5fac2e0227c2f65b9f56Test
https://pubmed.ncbi.nlm.nih.gov/18957027Test