-
1Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation
المؤلفون: Mi-Kyung Yun, Maksym Tsytlonok, Peter Tompa, Sivaraja Vaithiyalingam, Suren Felekyan, Claus A. M. Seidel, Aaron H. Phillips, Luigi I. Iconaru, Yuefeng Wang, Hugo Sanabria, Stephen W. White, M. Brett Waddell, Richard W. Kriwacki, Katherina Hemmen, Cheon-Gil Park
المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communicationsمصطلحات موضوعية: Threonine, 0301 basic medicine, Quantitative Biology - Subcellular Processes, Cell division, Cyclin A, Fusion Proteins, bcr-abl, General Physics and Astronomy, 02 engineering and technology, Crystallography, X-Ray, Quantitative Biology - Quantitative Methods, chemistry.chemical_compound, Phosphorylation, lcsh:Science, Quantitative Methods (q-bio.QM), Multidisciplinary, biology, Chemistry, 021001 nanoscience & nanotechnology, Recombinant Proteins, Cell biology, src-Family Kinases, 0210 nano-technology, Tyrosine kinase, Cell Division, Cyclin-Dependent Kinase Inhibitor p27, Protein Binding, Signal Transduction, Proto-oncogene tyrosine-protein kinase Src, Science, Molecular Dynamics Simulation, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cyclin-dependent kinase, Subcellular Processes (q-bio.SC), Cyclin-Dependent Kinase 2, Cyclin-dependent kinase 2, Tyrosine phosphorylation, Biomolecules (q-bio.BM), General Chemistry, Protein Structure, Tertiary, 030104 developmental biology, Quantitative Biology - Biomolecules, FOS: Biological sciences, Proteolysis, Mutagenesis, Site-Directed, biology.protein, Tyrosine, lcsh:Q, Protein Processing, Post-Translational
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebf5b582a25ff50bd576925e3ed1b6aTest
http://arxiv.org/abs/1812.07009Test -
2
المؤلفون: R. Kiplin Guy, Jaeki Min, Morten Grøtli, M. Brett Waddell, Emma Danelius, Máté Erdélyi, Mariell Pettersson, Matilda Bred
المصدر: Organicbiomolecular chemistry. 14(44)
مصطلحات موضوعية: Models, Molecular, Protein Conformation, alpha-Helical, 010402 general chemistry, 01 natural sciences, Biochemistry, Protein–protein interaction, Protein structure, Physical and Theoretical Chemistry, Surface plasmon resonance, Binding site, Flexibility (engineering), biology, 010405 organic chemistry, Drug discovery, Chemistry, Organic Chemistry, Proto-Oncogene Proteins c-mdm2, 3. Good health, 0104 chemical sciences, Drug Design, biology.protein, Mdm2, Peptidomimetics, Tumor Suppressor Protein p53, Fluorescence anisotropy, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6a1c220c8f7d006d5b434dbfa10340Test
https://pubmed.ncbi.nlm.nih.gov/27731454Test -
3
المؤلفون: Jaeki Min, M. Brett Waddell, Maria Quant, R. Kiplin Guy, Richard W. Kriwacki, Mariell Pettersson, Kristina Luthman, Luigi I. Iconaru, Morten Grøtli
المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0137867 (2015)مصطلحات موضوعية: Models, Molecular, Stereochemistry, lcsh:Medicine, Peptide, Chemistry Techniques, Synthetic, Diketopiperazines, Protein Structure, Secondary, Protein–protein interaction, chemistry.chemical_compound, Protein structure, Peptide synthesis, Humans, Binding site, lcsh:Science, chemistry.chemical_classification, Multidisciplinary, Binding Sites, lcsh:R, Rational design, Proto-Oncogene Proteins c-mdm2, Biochemistry, chemistry, Docking (molecular), Drug Design, lcsh:Q, Tumor Suppressor Protein p53, Research Article, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a46a51102ac919b0bd01d94c09075aTest
http://europepmc.org/articles/PMC4591261Test -
4
المؤلفون: Steven N. Seyedin, Timothy Hoggard, Jiang Liu, Amanda Nourse, Min Zhuang, Michal Hammel, David M. Duda, Kevin P. White, J. Wade Harper, Helen Walden, Matthew F. Calabrese, Darcie J. Miller, Brenda A. Schulman, M. Brett Waddell
المصدر: Molecular Cell. 36(1):39-50
مصطلحات موضوعية: Models, Molecular, Co-Repressor Proteins, Recombinant Fusion Proteins, Ubiquitin-Protein Ligases, Computational biology, SPOP, Crystallography, X-Ray, Article, Histones, Protein structure, Consensus Sequence, Phosphoprotein Phosphatases, Animals, Drosophila Proteins, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Protein Structure, Quaternary, Molecular Biology, Adaptor Proteins, Signal Transducing, biology, Cullin Proteins, Ubiquitination, Nuclear Proteins, Cell Biology, Peptide Fragments, Chromatin, Ubiquitin ligase, DNA-Binding Proteins, Repressor Proteins, Drosophila melanogaster, Biochemistry, Mutation, biology.protein, Protein Multimerization, Cullin, Molecular Chaperones, Protein Binding, Transcription Factors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3c3d9cbf9cfaab45e912fafb9471e2Test
-
5
المؤلفون: Susan Brophy, Xiaochun Qin, Rebecca L. Rich, Mary M. Murphy, Hann-Wen Guan, Nenad Tomasevic, Tanya Hayden, Giuseppe A. Papalia, Stephanie Leavitt, Brad Condon, Ta Deng, Fabio Parmeggiani, Thomas Heutmekers, Daniel Bedinger, Terry Nakagawa, Iva Navratilova, Tiffany Tsang, Bart Hoorelbeke, David G. Myszka, M. Brett Waddell, Fred Feiyu Zhang, Sabina Rebe, Mark C. McCroskey, Anne W Emerick
المصدر: Analytical Biochemistry, 364(1), 67-77
Analytical Biochemistry 364 (2007) 1مصطلحات موضوعية: Biomedical Research, binding, Carbonic anhydrase II, RIKILT - Business Unit Veiligheid & Gezondheid, Biophysics, Thermodynamics, Biosensing Techniques, Calorimetry, users, Carbonic Anhydrase II, equilibrium, Biochemistry, Dissociation (chemistry), surface, Surface plasmon resonance, Carbonic Anhydrase Inhibitors, Molecular Biology, Observer Variation, Sulfonamides, Chromatography, Chemistry, Protein protein, Isothermal titration calorimetry, Cell Biology, Surface Plasmon Resonance, Benchmarking, RIKILT - Business Unit Safety & Health, Observer variation, Biosensor, Protein Binding
وصف الملف: application/octet-stream; application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405bdba119b3472d89e841de4753f898Test
https://doi.org/10.1016/j.ab.2007.01.031Test -
6
المؤلفون: David M. Duda, Laura A. Borg, Mary-Ann Bjornsti, M. Brett Waddell, Brenda A. Schulman, Robert C.A.M. van Waardenburg, Amanda Nourse, Sierra McGarity
مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Molecular Sequence Data, Molecular Conformation, SUMO binding, SUMO enzymes, Plasma protein binding, Saccharomyces cerevisiae, Biology, Ubiquitin-conjugating enzyme, Crystallography, X-Ray, Article, Ubiquitin, Structural Biology, Small Ubiquitin-Related Modifier Proteins, Catalytic Domain, Humans, Amino Acid Sequence, Cysteine, Binding site, Cloning, Molecular, Molecular Biology, Sequence Homology, Amino Acid, Effector, Proteins, Cell biology, Repressor Proteins, Biochemistry, Ubiquitin-Conjugating Enzymes, biology.protein, Protein Binding
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0130a7febb824b9e831dbd4b9b8596dTest
https://europepmc.org/articles/PMC1936411Test/ -
7
المؤلفون: Matthias, Grimmler, Yuefeng, Wang, Thomas, Mund, Zoran, Cilensek, Eva-Maria, Keidel, M Brett, Waddell, Heidelinde, Jäkel, Michael, Kullmann, Richard W, Kriwacki, Ludger, Hengst
المصدر: Cell. 128(2)
مصطلحات موضوعية: Binding Sites, SKP Cullin F-Box Protein Ligases, Cyclin-Dependent Kinase 2, Fusion Proteins, bcr-abl, Oncogenes, Fibroblasts, Protein-Tyrosine Kinases, Cyclin-Dependent Kinases, Protein Structure, Tertiary, Gene Expression Regulation, Neoplastic, Mice, Cell Transformation, Neoplastic, src-Family Kinases, Animals, Humans, Phosphorylation, S-Phase Kinase-Associated Proteins, Cyclin-Dependent Kinase Inhibitor p27, HeLa Cells, Protein Binding, Signal Transduction
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::d2e90f68be6b0a228694cd2a422720f9Test
https://pubmed.ncbi.nlm.nih.gov/17254963Test