المؤلفون: Tomas-Roca, L., Qiu, Z., Fransén, Erik, 1962, Gokhale, R., Bulovaite, E., Price, D. J., Komiyama, N. H., Grant, S. G. N.

المصدر: Nature Communications. 13(1)

مصطلحات موضوعية: pentobarbital, transcription factor PAX6, PAX6 protein, human, Pax6 protein, mouse, brain, developmental biology, disease prevalence, nervous system disorder, protein, rodent, trajectory, turnover, animal experiment, animal model, animal tissue, Article, Bayes theorem, brain function, brain region, cognition, computer model, confocal microscopy, connectome, controlled study, disease model, electrophysiology, excitatory postsynaptic potential, functional magnetic resonance imaging, genetic disorder, genotype, haploinsufficiency, hippocampal CA1 region, mental disease, Monte Carlo method, nerve cell network, nonhuman, phenotype, postnatal development, protein metabolism, synapse, synaptic transmission, animal, genetics, metabolism, preschool child, Animals, Child, Preschool, Humans, Mice, Neurodevelopmental Disorders, PAX6 Transcription Factor, Synapses

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-329015Test
https://doi.org/10.1038/s41467-022-34131-wTest

المؤلفون: Chen, M.Z, Moily, N.S, Bridgford, J.L, Wood, R.J, Radwan, M, Smith, T.A, Song, Z, Tang, B.Z, Tilley, L, Xu, X, Reid, G.E, Pouladi, M.A, Hong, Y, Hatters, D.M

المساهمون: DEPT OF MEDICINE

المصدر: Unpaywall 20201031

مصطلحات موضوعية: beta lactoglobulin, cysteine, dihydroartemisinin, dye, enolase, globular protein, glutathione, huntingtin, peroxiredoxin 3, protein, proteome, tetraphenylethene maleimide, thiol, ubiquitin, unclassified drug, artemisinin derivative, epoxomicin, fluorescent dye, maleimide, maleimide derivative, mutant protein, oligopeptide, thiol derivative, tunicamycin, cells and cell components, nervous system disorder, parasite, proteomics, reaction kinetics, Article

العلاقة: Chen, M.Z, Moily, N.S, Bridgford, J.L, Wood, R.J, Radwan, M, Smith, T.A, Song, Z, Tang, B.Z, Tilley, L, Xu, X, Reid, G.E, Pouladi, M.A, Hong, Y, Hatters, D.M (2017). A thiol probe for measuring unfolded protein load and proteostasis in cells. Nature Communications 8 (1) : 474. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00203-5Test; https://scholarbank.nus.edu.sg/handle/10635/178580Test

الإتاحة: https://doi.org/10.1038/s41467-017-00203-5Test
https://scholarbank.nus.edu.sg/handle/10635/178580Test

المؤلفون: Brown A.-L., Wilkins O.G., Keuss M.J., Hill S.E., Zanovello M., Lee W.C., Bampton A., Lee F.C.Y., Masino L., Qi Y.A., Bryce-Smith S., Gatt A., Hallegger M., Fagegaltier D., Phatnani H., Kwan J., Sareen D., Broach J.R., Simmons Z., Arcila-Londono X., Lee E.B., Van Deerlin V.M., Shneider N.A., Fraenkel E., Ostrow L.W., Baas F., Zaitlen N., Berry J.D., Malaspina A., Fratta P., Cox G.A., Thompson L.M., Finkbeiner S., Dardiotis E., Miller T.M., Chandran S., Pal S., Hornstein E., MacGowan D.J., Heiman-Patterson T., Hammell M.G., Patsopoulos N.A., Butovsky O., Dubnau J., Nath A., Bowser R., Harms M., Aronica E., Poss M., Phillips-Cremins J., Crary J., Atassi N., Lange D.J., Adams D.J., Stefanis L., Gotkine M., Baloh R.H., Babu S., Raj T., Paganoni S., Shalem O., Smith C., Zhang B., Harris B., Broce I., Drory V., Ravits J., McMillan C., Menon V., Wu L., Altschuler S., Lerner Y., Sattler R., Van Keuren-Jensen K., Rozenblatt-Rosen O., Lindblad-Toh K., Nicholson K., Gregersen P., Lee J.-H., Kokos S., Muljo S., Newcombe J., Gustavsson E.K., Seddighi S., Reyes J.F., Coon S.L., Ramos D., Schiavo G., Fisher E.M.C., Secrier M., Lashley T., Ule J., Buratti E., Humphrey J., Ward M.E., NYGC ALS Consortium

المصدر: Nature ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85125039190&doi=10.1038%2fs41586-022-04436-3&partnerID=40&md5=6afcbfa9edcc1f8c16aba4b224a8e20fTest

مصطلحات موضوعية: TAR DNA binding protein, DNA binding protein, cell component, enzyme, enzyme activity, nervous system disorder, polymorphism, protein, adult, amyotrophic lateral sclerosis, Article, clinical article, down regulation, exon, gene, gene knockdown, genetic risk, human, human cell, male, nerve cell, RNA splicing, single nucleotide polymorphism, UNC13A gene, frontotemporal dementia, genetics, metabolism, TDP 43 proteinopathy, DNA-Binding Proteins, Humans

العلاقة: http://hdl.handle.net/11615/72164Test

الإتاحة: https://doi.org/10.1038/s41586-022-04436-3Test
http://hdl.handle.net/11615/72164Test

المؤلفون: Kouri, Naomi, Ross, Owen A., Dombroski, Beth, Younkin, Curtis S., Serie, Daniel J., Soto-Ortolaza, Alexandra, Baker, Matthew, Finch, Ni Cole A., Yoon, Hyejin, Kim, Jungsu, Fujioka, Shinsuke, McLean, Catriona A., Ghetti, Bernardino, Spina, Salvatore, Cantwell, Laura B., Farlow, Martin R., Grafman, Jordan, Huey, Edward D., Ryung Han, Mi, Beecher, Sherry, Geller, Evan T., Kretzschmar, Hans A., Roeber, Sigrun, Gearing, Marla, Juncos, Jorge L., Vonsattel, Jean Paul G., Van Deerlin, Vivianna M., Grossman, Murray, Hurtig, Howard I., Gross, Rachel G., Arnold, Steven E., Trojanowski, John Q., Lee, Virginia M., Wenning, Gregor K., White, Charles L., Höglinger, Günter U., Müller, Ulrich, Devlin, Bernie, Golbe, Lawrence I., Crook, Julia, Parisi, Joseph E., Boeve, Bradley F., Josephs, Keith A., Wszolek, Zbigniew K., Uitti, Ryan J., Graff-Radford, Neill R., Litvan, Irene, Younkin, Steven G., Wang, Li-San, Ertekin-Taner, Nilüfer, Rademakers, Rosa, Hakonarsen, Hakon, Schellenberg, Gerard D., Dickson, Dennis W.

المساهمون: Department of Pathology & Laboratory Medicine, IU School of Medicine

المصدر: Publisher

مصطلحات موضوعية: supranuclear palsy, nervous system disorder, meta-analysis, brain, genetic analysis, genome, protein, polymorphism, cognition, risk factor, RNA

وصف الملف: application/pdf

العلاقة: Nature Communications; Kouri, N., Ross, O. A., Dombroski, B., Younkin, C. S., Serie, D. J., Soto-Ortolaza, A., … Dickson, D. W. (2015). Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy. Nature Communications, 6, 7247. http://doi.org/10.1038/ncomms8247Test; https://hdl.handle.net/1805/8947Test

الإتاحة: https://doi.org/10.1038/ncomms8247Test
https://hdl.handle.net/1805/8947Test

المؤلفون: Li S., Koe C.T., Tay S.T., Tan A.L.K., Zhang S., Zhang Y., Tan P., Sung W.-K., Wang H.

المساهمون: DUKE-NUS MEDICAL SCHOOL, PHYSIOLOGY, DEPT OF COMPUTER SCIENCE

المصدر: Unpaywall 20200831

مصطلحات موضوعية: insulin, matrix protein, phosphatidylinositol 3 kinase, protein Chromator, somatomedin, transcription factor, transcription factor Grainy head, transcription factor Prospero, unclassified drug, chromator protein, Drosophila, DNA binding protein, Drosophila protein, EAST protein, grh protein, megator protein, nerve protein, nuclear matrix protein, nuclear protein, phosphoprotein, pros protein, biochemistry, biological development, cells and cell components, gene expression, growth, hormone, nervous system disorder, physiology, protein

العلاقة: Li S., Koe C.T., Tay S.T., Tan A.L.K., Zhang S., Zhang Y., Tan P., Sung W.-K., Wang H. (2017). An intrinsic mechanism controls reactivation of neural stem cells by spindle matrix proteins. Nature Communications 8 (1) : 122. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00172-9Test; https://scholarbank.nus.edu.sg/handle/10635/174488Test

الإتاحة: https://doi.org/10.1038/s41467-017-00172-9Test
https://scholarbank.nus.edu.sg/handle/10635/174488Test

المؤلفون: Wang, Y.-H, Hariharan, A, Bastianello, G, Toyama, Y, Shivashankar, G.V, Foiani, M, Sheetz, M.P

المساهمون: MECHANOBIOLOGY INSTITUTE, BIOLOGICAL SCIENCES, BIOLOGY (NU)

المصدر: Unpaywall 20200831

مصطلحات موضوعية: actin, ATR protein, cell nucleus receptor, checkpoint kinase 1, inositol polyphosphate, inositol polyphosphate multikinase, latrunculin A, messenger RNA, nuclear protein, nuclear receptor protein SF1, phosphatidylinositide, unclassified drug, wortmannin, ATM protein, human, CHEK1 protein, phosphatidylinositol, phosphotransferase, steroidogenic factor 1, chemical reaction, DNA, enzyme, enzyme activity, metabolism, nervous system disorder, protein, animal cell, Article, controlled study, DNA damage response

العلاقة: Wang, Y.-H, Hariharan, A, Bastianello, G, Toyama, Y, Shivashankar, G.V, Foiani, M, Sheetz, M.P (2017). DNA damage causes rapid accumulation of phosphoinositides for ATR signaling. Nature Communications 8 (1) : 2118. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-01805-9Test; https://scholarbank.nus.edu.sg/handle/10635/174372Test

الإتاحة: https://doi.org/10.1038/s41467-017-01805-9Test
https://scholarbank.nus.edu.sg/handle/10635/174372Test

المؤلفون: Chintalapudi, S.R, Maria, D, Di Wang, X, Bailey, J.N.C, Allingham, R, Brilliant, M, Budenz, D, Fingert, J, Gaasterland, D, Gaasterland, T, Haines, J.L, Hark, L, Hauser, M, Igo, R, Hee Kang, J, Kraft, P, Lee, R, Lichter, P, Liu, Y, Moroi, S, Pasquale, L.R, Pericak-Vance, M, Realini, A, Rhee, D, Richards, J.R, Ritch, R, Schuman, J, Scott, W.K, Singh, K, Sit, A, Vollrath, D, Wollstein, G, Zack, D, Aung, T, Bonnemaijer, P, Cheng, C.-Y, Craig, J, Van Duijn, C, Gharahkhani, P, Iglesias Gonzalez, A, Hammond, C.J, Hewitt, A, Hoehn, R, Jonansson, F, Khawaja, A, Chuen Khor, C, Klaver, C.C.W, Lotery, A, MacKey, D, MacGregor, S, Pang, C, Pasutto, F, Stefansson, K, Thorleifsson, G, Thorsteinsdottir, U, Vitart, V, Vithana, E, Young, T, Zeller, T, Hysi, P.G, Wiggs, J.L, Williams, R.W, Jablonski, M.M

المساهمون: DUKE-NUS MEDICAL SCHOOL, DEPT OF OPHTHALMOLOGY, DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)

المصدر: Unpaywall 20200831

مصطلحات موضوعية: cacna2d1 protein, pregabalin, protein, unclassified drug, human, mouse, calcium channel, chemical binding, genetic analysis, genetic variation, nervous system disorder, polymerase chain reaction, polymorphism, risk factor, aged, animal experiment, animal model, animal tissue, Article, case report, cellular distribution, clinical article, controlled study, drug protein binding, female, genetic association, genetic susceptibility, genetic variability, genome-wide association study, glaucoma

العلاقة: Chintalapudi, S.R, Maria, D, Di Wang, X, Bailey, J.N.C, Allingham, R, Brilliant, M, Budenz, D, Fingert, J, Gaasterland, D, Gaasterland, T, Haines, J.L, Hark, L, Hauser, M, Igo, R, Hee Kang, J, Kraft, P, Lee, R, Lichter, P, Liu, Y, Moroi, S, Pasquale, L.R, Pericak-Vance, M, Realini, A, Rhee, D, Richards, J.R, Ritch, R, Schuman, J, Scott, W.K, Singh, K, Sit, A, Vollrath, D, Wollstein, G, Zack, D, Aung, T, Bonnemaijer, P, Cheng, C.-Y, Craig, J, Van Duijn, C, Gharahkhani, P, Iglesias Gonzalez, A, Hammond, C.J, Hewitt, A, Hoehn, R, Jonansson, F, Khawaja, A, Chuen Khor, C, Klaver, C.C.W, Lotery, A, MacKey, D, MacGregor, S, Pang, C, Pasutto, F, Stefansson, K, Thorleifsson, G, Thorsteinsdottir, U, Vitart, V, Vithana, E, Young, T, Zeller, T, Hysi, P.G, Wiggs, J.L, Williams, R.W, Jablonski, M.M (2017). Systems genetics identifies a role for Cacna2d1 regulation in elevated intraocular pressure and glaucoma susceptibility. Nature Communications 8 (1) : 1755. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00837-5Test; https://scholarbank.nus.edu.sg/handle/10635/174380Test

الإتاحة: https://doi.org/10.1038/s41467-017-00837-5Test
https://scholarbank.nus.edu.sg/handle/10635/174380Test

المؤلفون: Kapeli, K, Pratt, G.A, Vu, A.Q, Hutt, K.R, Martinez, F.J, Sundararaman, B, Batra, R, Freese, P, Lambert, N.J, Huelga, S.C, Chun, S.J, Liang, T.Y, Chang, J, Donohue, J.P, Shiue, L, Zhang, J, Zhu, H, Cambi, F, Kasarskis, E, Hoon, S, Ares, M, Burge, C.B, Ravits, J, Rigo, F, Yeo, G.W

المساهمون: PHYSIOLOGY

المصدر: Unpaywall 20200831

مصطلحات موضوعية: fused in sarcoma protein, messenger RNA, protein TAF15, RNA, RNA binding protein, TAR DNA binding protein, unclassified drug, antisense oligonucleotide, DNA binding protein, FUS protein, human, mouse, RNA binding protein FUS, small interfering RNA, TAF15 protein, TATA binding protein associated factor, TDP-43 protein, brain, chemical binding, genetic engineering, genetic marker, mutation, nervous system disorder, protein, rodent, 3' untranslated region, 5' untranslated region, adult, alternative RNA splicing, amyotrophic lateral sclerosis

العلاقة: Kapeli, K, Pratt, G.A, Vu, A.Q, Hutt, K.R, Martinez, F.J, Sundararaman, B, Batra, R, Freese, P, Lambert, N.J, Huelga, S.C, Chun, S.J, Liang, T.Y, Chang, J, Donohue, J.P, Shiue, L, Zhang, J, Zhu, H, Cambi, F, Kasarskis, E, Hoon, S, Ares, M, Burge, C.B, Ravits, J, Rigo, F, Yeo, G.W (2016). Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nature Communications 7 : 12143. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms12143Test; https://scholarbank.nus.edu.sg/handle/10635/174950Test

الإتاحة: https://doi.org/10.1038/ncomms12143Test
https://scholarbank.nus.edu.sg/handle/10635/174950Test