التفاصيل البيبلوغرافية
| العنوان: |
Dietary protein intake and mortality among survivors of liver cirrhosis: a prospective cohort study. |
| المؤلفون: |
Daftari, Ghazal, Tehrani, Asal Neshatbini, Pashayee-khamene, Fereshteh, Karimi, Sara, Ahmadzadeh, Saleheh, Hekmatdoost, Azita, Salehpour, Amin, Saber-Firoozi, Mahdi, Hatami, Behzad, Yari, Zahra |
| المصدر: |
BMC Gastroenterology; 7/3/2023, Vol. 23 Issue 1, p1-11, 11p |
| مصطلحات موضوعية: |
DIETARY proteins, FOOD consumption, CIRRHOSIS of the liver, COHORT analysis, LONGITUDINAL method, ESOPHAGEAL varices |
| مستخلص: |
Background: Liver cirrhosis is a worldwide burden and is associated with poor clinical outcomes, including increased mortality. The beneficial effects of dietary modifications in reducing morbidity and mortality are inevitable. Aim: The current study aimed to evaluate the potential association of dietary protein intake with the cirrhosis-related mortality. Methods: In this cohort study, 121 ambulatory cirrhotic patients with at least 6 months of cirrhosis diagnosis were followed-up for 48 months. A 168-item validated food frequency questionnaire was used for dietary intake assessment. Total dietary protein was classified as dairy, vegetable and animal protein. We estimated crude and multivariable-adjusted hazard ratios (HRs) with 95% confidence intervals (CIs), applying Cox proportional hazard analyses. Results: After full adjustment for confounders, analyses showed that total (HR = 0.38, 95% CI = 0.2–1.1, p trend = 0.045) and dairy (HR = 0.38, 95% CI = 0.13–1.1, p trend = 0.046) protein intake was associated with a 62% lower risk of cirrhosis-related mortality. While a higher intake of animal protein was associated with a 3.8-fold increase in the risk of mortality in patients (HR = 3.8, 95% CI = 1.7–8.2, p trend = 0.035). Higher intake of vegetable protein was inversely but not significantly associated with mortality risk. Conclusion: A comprehensive evaluation of the associations of dietary protein intake with cirrhosis-related mortality indicated that a higher intakes of total and dairy protein and a lower intakes of animal protein are associated with a reduced risk of mortality in cirrhotic patients. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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