المؤلفون: Macartney, Malcolm J.¹ malcolm.macartney@nhs.net, Irish, Dianne¹, Bridge, Simon H.¹, Garcia-Diaz, Ana¹, Booth, Clare L.¹, McCormick, Adele L.¹, Labbett, Wendy¹, Smith, Colette², Velazquez, Carmen³, Tanwar, Sudeep⁴, Trembling, Paul⁴, Jacobs, Michael³, Dusheiko, Geoff³, Rosenberg, William^3,4, Haque, Tanzina¹

المصدر: Antiviral Research. May2014, Vol. 105, p112-117. 6p.

مصطلحات موضوعية: *TELAPREVIR, *BOCEPREVIR, *VIRUS diseases, *HEPATITIS C treatment, *DRUG resistance, *VIRAL load, *THERAPEUTICS

المؤلفون: Vanessa Duarte da Costa, Paulo Sergio Fonseca de Sousa, Carlos Eduardo Brandão-Mello, Lia Laura Lewis Ximenez de Souza Rodrigues, Elisabeth Lampe, Francisco C. A. Mello, Estevão Portela Nunes, Nathália Delvaux

المصدر: Clinics and Research in Hepatology and Gastroenterology. 43:700-706

مصطلحات موضوعية: Adult, Male, Simeprevir, Daclatasvir, Genotype, Sofosbuvir, Hepacivirus, Viral Nonstructural Proteins, Antiviral Agents, Telaprevir, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Boceprevir, Drug Resistance, Viral, medicine, Humans, Protease Inhibitors, NS3, Hepatology, business.industry, Gastroenterology, virus diseases, Hepatitis C, Hepatitis C, Chronic, medicine.disease, Virology, chemistry, 030220 oncology & carcinogenesis, Female, 030211 gastroenterology & hepatology, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6554bcf5174fea8849730829a36c694Test
https://doi.org/10.1016/j.clinre.2019.02.009Test

المؤلفون: Yuyong Zhou, Troels K. H. Scheel, Shan Feng, Jens Bukh, Karen A. Gammeltoft, Santseharay Ramirez, Judith M. Gottwein, Long V. Pham, Anna Offersgaard, Andrea Galli, Rui Costa, Carlos Rene Duarte Hernandez, Ulrik Fahnøe

المصدر: Antimicrobial Agents and Chemotherapy
Gammeltoft, K A, Zhou, Y, Duarte Hernandez, C R, Galli, A, Offersgaard, A, Costa, R, Pham, L V, Fahnøe, U, Feng, S, Scheel, T K H, Ramirez, S, Bukh, J & Gottwein, J M 2021, ' Hepatitis C Virus Protease Inhibitors Show Differential Efficacy and Interactions with Remdesivir for Treatment of SARS-CoV-2 in Vitro ', Antimicrobial Agents and Chemotherapy, vol. 65, no. 9, e02680-20 . https://doi.org/10.1128/AAC.02680-20Test

مصطلحات موضوعية: Viral Protease Inhibitors, Voxilaprevir, Vaniprevir, viruses, coronavirus, repurposing, synergy, Hepacivirus, Antiviral Agents, Telaprevir, chemistry.chemical_compound, Boceprevir, Chlorocebus aethiops, medicine, Animals, Humans, Pharmacology (medical), Protease Inhibitors, Vero Cells, Pharmacology, Alanine, SARS-CoV-2, Danoprevir, virus diseases, COVID-19, Glecaprevir, Hepatitis C, Chronic, Virology, Hepatitis C, antiviral, Adenosine Monophosphate, COVID-19 Drug Treatment, Infectious Diseases, Grazoprevir, chemistry, Narlaprevir, Spike Glycoprotein, Coronavirus, combination treatment, medicine.drug

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fc2c433c7de0ed40ca06a8bfe3c408Test
https://pubmed.ncbi.nlm.nih.gov/34097489Test

المؤلفون: Peihua Niu, Cheng Zhao, Yan Wu, George F. Gao, Wenjie Tan, Hao Song, Qisheng Wang, Fei Ye, Yong Feng, Huan Sun, Jianxun Qi, Baoying Huang, Yi Shi, Lifeng Fu, Feng Yu, Xuebing Li

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Pyrrolidines, medicine.medical_treatment, viruses, General Physics and Astronomy, 02 engineering and technology, Viral Nonstructural Proteins, medicine.disease_cause, Crystallography, X-Ray, Virus Replication, chemistry.chemical_compound, Catalytic Domain, Chlorocebus aethiops, lcsh:Science, Coronavirus 3C Proteases, Coronavirus, Multidisciplinary, Nanocrystallography, High-throughput screening, virus diseases, Proteases, 021001 nanoscience & nanotechnology, Cysteine Endopeptidases, 0210 nano-technology, Coronavirus Infections, Proline, Science, Pneumonia, Viral, RNA-dependent RNA polymerase, Biology, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Virus, Article, 03 medical and health sciences, Betacoronavirus, Boceprevir, medicine, Animals, Protease Inhibitors, Pandemics, Vero Cells, Protease, Binding Sites, SARS-CoV-2, COVID-19, General Chemistry, biochemical phenomena, metabolism, and nutrition, RNA-Dependent RNA Polymerase, Virology, Feline infectious peritonitis, High-Throughput Screening Assays, COVID-19 Drug Treatment, Disease Models, Animal, 030104 developmental biology, chemistry, Vero cell, lcsh:Q, Sulfonic Acids

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1944eab284fa289b9ee413e830e95f5Test
http://europepmc.org/articles/PMC7474075Test

المؤلفون: Chunyang Li, Danhui Sun, Xuebing Yan, Mingjia Dai, Shanshan Shen

المصدر: Gene Expression. 18:63-69

مصطلحات موضوعية: Adult, Male, Genotype, medicine.medical_treatment, Hepatitis C virus, Context (language use), Hepacivirus, Drug resistance, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Article, Telaprevir, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Boceprevir, Drug Resistance, Viral, Genetics, Humans, Medicine, Protease Inhibitors, NS5A, Molecular Biology, NS3, Protease, business.industry, virus diseases, Hepatitis C, Chronic, Middle Aged, Virology, digestive system diseases, chemistry, 030220 oncology & carcinogenesis, Mutation, Female, 030211 gastroenterology & hepatology, Serine Proteases, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8560f57b3a4315c2b65116d0bef27afTest
https://doi.org/10.3727/105221617x15100607143377Test

المؤلفون: Gene D. Morse, Adeel A. Butt, Kenneth E. Sherman, Susan L. Rosenkranz, Robin DiFrancesco, Jennifer J. Kiser, Darlene Lu

المصدر: Drugs in R&D

مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Efavirenz, Proline, Anti-HIV Agents, 030106 microbiology, Population, HIV Infections, Hepacivirus, 030226 pharmacology & pharmacy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, Boceprevir, Internal medicine, medicine, Humans, Drug Interactions, Protease Inhibitors, Original Research Article, education, Darunavir, Pharmacology, education.field_of_study, business.industry, virus diseases, Lopinavir, Hepatitis C, Middle Aged, medicine.disease, Raltegravir, Virology, 3. Good health, Atazanavir, chemistry, Drug Therapy, Combination, Female, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dcbd6c634a384fe5acf53537e482214Test
http://europepmc.org/articles/PMC5694418Test

المؤلفون: Didier Samuel, Bruno Roche, A.-M. Roque-Afonso, Audrey Coilly

المصدر: Viruses
Viruses, Vol 7, Iss 9, Pp 5155-5168 (2015)

مصطلحات موضوعية: ledipasvir, Sofosbuvir, medicine.medical_treatment, lcsh:QR1-502, Review, Hepacivirus, Liver transplantation, medicine.disease_cause, Gastroenterology, lcsh:Microbiology, Telaprevir, chemistry.chemical_compound, Pegylated interferon, antiviral therapy, boceprevir, dasabuvir, liver transplantation, virus diseases, Hepatitis C, interferon, Infectious Diseases, Treatment Outcome, medicine.drug, medicine.medical_specialty, Drug-Related Side Effects and Adverse Reactions, ribavirin, Hepatitis C virus, simeprevir, sofosbuvir, Antiviral Agents, Virology, Boceprevir, Internal medicine, Drug Resistance, Viral, medicine, Humans, telaprevir, Protease Inhibitors, daclatasvir, direct-acting antiviral, business.industry, paritaprevir, Hepatitis C, Chronic, medicine.disease, digestive system diseases, ombitasvir, chemistry, Paritaprevir, Immunology, hepatitis C, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::082cd0cf3cc96f3ffc9ea640d56fdf72Test
http://europepmc.org/articles/PMC4584308Test

المؤلفون: Kostić, Milotka Fabri, Janković G, Ksenija Bojovic, Babić Js, Zeljko Mijailovic, Petar Svorcan, Jovanović M

المصدر: Srpski Arhiv za Celokupno Lekarstvo, Vol 143, Iss 1-2, Pp 35-41 (2015)

مصطلحات موضوعية: Liver Cirrhosis, medicine.medical_specialty, Cirrhosis, Genotype, Proline, Anemia, lcsh:Medicine, Hepacivirus, Antiviral Agents, Gastroenterology, protease inhibitor, chemistry.chemical_compound, Pegylated interferon, Boceprevir, Internal medicine, Ribavirin, boceprevir, medicine, Humans, chronic hepatitis C, Protease Inhibitors, Adverse effect, business.industry, lcsh:R, virus diseases, General Medicine, Hepatitis C, Chronic, medicine.disease, digestive system diseases, Surgery, Regimen, chemistry, Tolerability, Drug Therapy, Combination, business, Serbia, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a8457daea44683bfd96eadf30bb84eTest
https://doi.org/10.2298/sarh1502035sTest

المؤلفون: Azat Mukhametov

المصدر: Current Topics in Medicinal Chemistry. 16:1351-1361

مصطلحات موضوعية: Hepatitis C virus, Hepacivirus, Population, Molecular Conformation, Microbial Sensitivity Tests, Drug resistance, Viral Nonstructural Proteins, Virus Replication, medicine.disease_cause, Antiviral Agents, Telaprevir, chemistry.chemical_compound, Boceprevir, Drug Discovery, medicine, Humans, Computer Simulation, Protease Inhibitors, education, NS3, education.field_of_study, biology, business.industry, virus diseases, General Medicine, Hepatitis C, biology.organism_classification, medicine.disease, Virology, digestive system diseases, chemistry, Quantum Theory, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd39471cf8706f7f82aa8967f723efaTest
https://doi.org/10.2174/1568026616666151120112141Test

المؤلفون: Sanaullah Khan, Muhammad Arshad Malik, Sobia Attaullah, Muhammad Akbar Shah, Hafeez Ullah Khan

المصدر: PLoS ONE, Vol 15, Iss 4, p e0231480 (2020)
PLoS ONE

مصطلحات موضوعية: Male, RNA viruses, 0301 basic medicine, Simeprevir, Hepacivirus, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Gastroenterology, Telaprevir, Geographical Locations, chemistry.chemical_compound, 0302 clinical medicine, Medicine and Health Sciences, Pakistan, Public and Occupational Health, Enzyme Inhibitors, Pathology and laboratory medicine, Sanger sequencing, Protease Inhibitor Therapy, Multidisciplinary, Hepatitis C virus, Database and informatics methods, Sequence analysis, virus diseases, Middle Aged, Medical microbiology, Vaccination and Immunization, Viruses, symbols, Medicine, Female, 030211 gastroenterology & hepatology, Pathogens, Research Article, medicine.drug, Adult, medicine.medical_specialty, Substitution Mutation, Asia, Genotype, Bioinformatics, Science, Immunology, 030106 microbiology, Antiretroviral Therapy, Antiviral Agents, Microbiology, Virus, 03 medical and health sciences, symbols.namesake, Antiviral Therapy, Microbial Control, Internal medicine, Boceprevir, Drug Resistance, Viral, Genetics, medicine, Humans, Protease Inhibitors, DNA sequence analysis, Pharmacology, NS3, Polymorphism, Genetic, Flaviviruses, business.industry, Organisms, Viral pathogens, Biology and Life Sciences, Sequence Analysis, DNA, Hepatitis C, Chronic, Hepatitis viruses, digestive system diseases, Microbial pathogens, Research and analysis methods, chemistry, Paritaprevir, Mutation, People and Places, Enzymology, Antimicrobial Resistance, Preventive Medicine, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7b36d7f690de3690601569d4efc68aTest
https://doi.org/10.1371/journal.pone.0231480Test