دورية أكاديمية
Cytomegalovirus infection management in solid organ transplant recipients across European centers in the time of molecular diagnostics: An ESGICH survey
| العنوان: | Cytomegalovirus infection management in solid organ transplant recipients across European centers in the time of molecular diagnostics: An ESGICH survey |
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| المؤلفون: | Navarro D., San-Juan R., Manuel O., Gimenez E., Fernandez-Ruiz M., Hirsch H. H., Grossi P. A., Aguado J. M., Abram M., Abramowicz D., Alamo J. -M., Alp S., Andres-Belmonte A., Anne-Catherine P., Antonelli B., Arnol M., Arslan A. H., Asderakis A., Baldanti F., Beneyto-Castello I., Benoit K. M., Blanes M., Boggian K., Bonofiglio R., Bubonja-Sonje M., Caillard S., Calvo J., Capone A., Cappelli G., Carmellini M., Casafont F., Beatriz Castro-Hernandez M., Catalan P., Celine B. -B., Christoph B., Cordero E., Costa C., Coussement J., Cuervas-Mons V., David M., de la Torre Cisneros J., Delgado J. F., Dello Strologo L., Detry O., Dexter L., Dieter H., Meis-Hubinger A., Epailly E., Ericzon B. -G., Eriksson B. -M., Fehervari I., FitzGerald S., Folgueira L., Fortun J., Franceschini E., Francois P., Friman V., Frimmel S., Garzoni C., Gimeno A., Gkrania-Klotsas E., Greer M., Griffiths P., Grinyo J. M., Guaraldi G., Gupte G., Hammad A., Hart I., Helantera I., Hellemans R., Hernandez D., Herrero J. I., Hiesse C., Hoppe-Lotichius M., Hryniewiecka E., Jaksch P., Jan L., Paul B. J., Jensen-Fangel S., Joerg S., Johan V., Johannessen I., Johansson I., Kamar N., Kizilates F., Knoop C., Laurent B., Lauro A., Lautenschlager I., Lauzurica R., Liebert U. G., dela Monica P., Llado L., Lopez-Andujar R., Luciani F., Maccherini M., Maertens J., Maggiore U., Manrique A., Marcos M. A., Marekovic I., Marques N., Martin N., Martine N., Martinez-Sapina A., Mateos Lindemann M. L., Mazuecos A., Merino E., Moreso F., Mueller N., Muir D., Mularoni A., Munoz P., Munoz-Sanz A., Nadalin S., Laura Ambra N., Nosotti M., Gorman J. O., Osman H., Padalko E., Palop-Borras B., Javirparmer, Pascual S., Pena Lopez M. J., Perez-Saenz J. L., Pistello M., Francisca Portero M., Puchhammer E., Racca S., Rahamat-Langendoen J., Ramos A., Boluda E. R., Raza M., Regalia E., Reina G., Reischig T., Reuter S., Rodriguez-Ferrero M. L., Roilides E., Rolla S., Rollag H., Rostaing L., Russo F. P., Sabe N., Saliba F., Sanchez-Fructuoso A., Scotton G., Serra N., Sgarabotto D., Stojanovic J., Tasbakan M., Telenti M., Terhes G., Thorban S., Tihic N., Travi G., Tulissi P., Van Delden C., Van Leer C., Van Loo I., Varona-Bosque M. A., Veroux M., Vila-Santandreu A., Waugh S., Zibar L., Zschiedr S. |
| المساهمون: | Navarro, D., San-Juan, R., Manuel, O., Gimenez, E., Fernandez-Ruiz, M., Hirsch, H. H., Grossi, P. A., Aguado, J. M., Abram, M., Abramowicz, D., Alamo, J. -M., Alp, S., Andres-Belmonte, A., Anne-Catherine, P., Antonelli, B., Arnol, M., Arslan, A. H., Asderakis, A., Baldanti, F., Beneyto-Castello, I., Benoit, K. M., Blanes, M., Boggian, K., Bonofiglio, R., Bubonja-Sonje, M., Caillard, S., Calvo, J., Capone, A., Cappelli, G., Carmellini, M., Casafont, F., Beatriz Castro-Hernandez, M., Catalan, P., Celine, B. -B., Christoph, B., Cordero, E., Costa, C., Coussement, J., Cuervas-Mons, V., David, M., de la Torre Cisneros, J., Delgado, J. F., Dello Strologo, L., Detry, O., Dexter, L., Dieter, H., Meis-Hubinger, A., Epailly, E., Ericzon, B. -G., Eriksson, B. -M., Fehervari, I., Fitzgerald, S., Folgueira, L., Fortun, J., Franceschini, E., Francois, P., Friman, V., Frimmel, S., Garzoni, C., Gimeno, A., Gkrania-Klotsas, E., Greer, M., Griffiths, P., Grinyo, J. M., Guaraldi, G., Gupte, G., Hammad, A., Hart, I., Helantera, I., Hellemans, R., Hernandez, D., Herrero, J. I., Hiesse, C., Hoppe-Lotichius, M., Hryniewiecka, E., Jaksch, P., Jan, L., Paul, B. J., Jensen-Fangel, S., Joerg, S., Johan, V., Johannessen, I., Johansson, I., Kamar, N., Kizilates, F., Knoop, C., Laurent, B., Lauro, A., Lautenschlager, I., Lauzurica, R., Liebert, U. G., dela Monica, P., Llado, L., Lopez-Andujar, R., Luciani, F., Maccherini, M., Maertens, J., Maggiore, U., Manrique, A., Marcos, M. A. |
| سنة النشر: | 2017 |
| المجموعة: | Università degli Studi di Siena: USiena air |
| مصطلحات موضوعية: | cytomegaloviru, solid organ transplantation, survey, Antibiotic Prophylaxi, Antiviral Agent, Cross-Sectional Studie, Cytomegalovirus Infection, DNA, Viral, Europe, Guideline Adherence, Health Care Survey, Human, Immunocompromised Host, Immunosuppression, Organ Transplantation, Postoperative Complication, Practice Guidelines as Topic, Practice Patterns, Physicians', Real-Time Polymerase Chain Reaction, Transplant Recipient, Transplant, Viral Load |
| الوصف: | Background: Scant information is available about how transplant centers are managing their use of quantitative molecular testing (QNAT) assays for active cytomegalovirus (CMV) infection monitoring in solid organ transplant (SOT) recipients. The current study was aimed at gathering information on current practices in the management of CMV infection across European centers in the era of molecular testing assays. Methods: A questionnaire-based cross-sectional survey study was conducted by the European Study Group of Infections in Immunocompromised Hosts (ESGICH) of the Society of Clinical Microbiology and Infectious Diseases (ESCMID). The invitation and a weekly reminder with a personal link to an Internet service provider (https://es.surveymonkey.comTest/) was sent to transplant physicians, transplant infectious diseases specialists, and clinical virologists working at 340 European transplant centers. Results: Of the 1181 specialists surveyed, a total of 173 responded (14.8%): 73 transplant physicians, 57 transplant infectious diseases specialists, and 43 virologists from 173 institutions located at 23 different countries. The majority of centers used QNAT assays for active CMV infection monitoring. Most centers preferred commercially available real-time polymerase chain reaction (RT-PCR) assays over laboratory-developed procedures for quantifying CMV DNA load in whole blood or plasma. Use of a wide variety of DNA extraction platforms and RT-PCR assays was reported. All programs used antiviral prophylaxis, preemptive therapy, or both, according to current guidelines. However, the centers used different criteria for starting preemptive antiviral treatment, for monitoring systemic CMV DNA load, and for requesting genotypic assays to detect emerging CMV-resistant variants. Conclusions: Significant variation in CMV infection management in SOT recipients still remains across European centers in the era of molecular testing. International multicenter studies are required to achieve commutability of CMV testing and antiviral ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/28859257; info:eu-repo/semantics/altIdentifier/wos/WOS:000418829500012; volume:19; issue:6; firstpage:1; lastpage:12; numberofpages:12; journal:TRANSPLANT INFECTIOUS DISEASE; http://hdl.handle.net/11365/1077841Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85032182572; http://www.wiley.com/bw/editors.asp?ref=1398-2273&site=1Test |
| DOI: | 10.1111/tid.12773 |
| الإتاحة: | https://doi.org/10.1111/tid.12773Test http://hdl.handle.net/11365/1077841Test http://www.wiley.com/bw/editors.asp?ref=1398-2273&site=1Test |
| حقوق: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.A497B19A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/tid.12773 |
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